4篇
您的检索式：作者名="Lukman Hakim"
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| 1 | Bone-Targeted Therapies for Elderly Patients with Renal Cell Carcinoma: Current and Future Directions显示文摘 | Thomas Roza Lukman Hakim Hendrik Poppel Steven Joniau | 2013 | Drugs & Aging2013，，11： | 1 |
| 2 | 棱果榕乙酸乙酯萃取物和阿霉素化疗对人类乳腺癌细胞T47D的协同效应(英文)显示文摘目的:以往研究已证实,棱果榕树叶的乙醇提取物及其乙酸乙酯萃取物(ethyl acetate soluble fraction,EASF)对人类乳腺癌细胞T47D有很强的细胞毒效应。本研究将进一步明确棱果榕树叶乙醇提取物的EASF联合阿霉素对人类乳腺癌T47D细胞系在细胞毒性、细胞周期阻滞以及诱导细胞凋亡方面的协同效应。方法:使用溴化噻唑蓝四氮唑比色法分析T47D细胞毒性效应,流式细胞仪进行细胞周期分析,ModFitLT3.0程序进行数据处理;采用溴化乙锭/吖啶橙双染色法检测细胞凋亡;免疫组织化学法识别T47D细胞系的聚ADP-核苷酸聚合酶(poly ADP-ribose polymerase,PARP)的表达。结果:EASF(0.875~7μg/mL)与阿霉素(2~8nmol/L)联合使用比单纯使用阿霉素能更有效地抑制T47D细胞生长。此外,二者联合使用能够增加细胞凋亡的发生率。研究发现,EASF能通过改变细胞从G2/M期至G1期而增强阿霉素的细胞毒效应。并且,二者的结合比单独使用能刺激T47D细胞中裂解性PARP的表达。结论:EASF可以通过诱导细胞凋亡和细胞周期停滞加强T47D细胞中的阿霉素活性。 | Agung E.Nugroho Adam Hermawan Dyaningtyas D.P.Putri Edy Meiyanto Lukman Hakim | 2012 | 中西医结合学报2012，10，10： | 0 |
| 3 | Daily activities and training experiences of urology residents during the coronavirus disease 2019 pandemic in Indonesia: A nationwide survey显示文摘Objective:To explore the impact of the coronavirus disease 2019(COVID-19)pandemic on the training experiences of urology residents in Indonesia.Methods:A cross-sectional study using a web-based questionnaire(SurveyMonkey)involved all registered urology residents in Indonesia.The questionnaire was structured in Bahasa Indonesia,composed of 28 questions,and divided into three sections:demographic characteristics,current daily activities,and opinions regarding training experiences during the COVID-19 outbreak.The survey was distributed to all respondents via chief of residents in each urology center from May 26,2020 to Jun 2,2020.Results:Of the total 247 registered urology residents,243 were eligible for the study.The response and completeness rate for this study were 243/243(100%).The median age of respondents was 30(range:24e38)years old,and 92.2%of them were male.Among them,6(2.5%)respondents were confirmed as COVID-19 positive.A decrease in residents’involvement in clinical and surgical activities was distinguishable in endourological and open procedures.Most educational activities were switched to web-based video conferences,while others opted for the in-person method.Smart learning methods,such as joining a national or international speaker webinar or watching a recorded video,were used by 93.8%and 80.7%of the respondents,respectively.The respondents thought that educational activities using web-based video conferences and smart learning methods were effective methods of learning.Overall,the respondents felt unsure whether training experiences during the COVID-19 pandemic were comparable to the respective period before.Conclusion:The COVID-19 pandemic negatively affected urology residents’training experiences.However,it also opened up new possibilities for incorporating new learning methodologies in the future. | Ponco Birowo Nur Rasyid Chaidir A.Mochtar Bambang S.Noegroho H.R.Danarto Besut Daryanto Lukman Hakim Dyandra Parikesit Fakhri Rahman S.Cahyo Ariwicaksono | 2023 | Asian Journal of Urology2023，10，2： | 0 |
| 4 | The Life Assessment of API 5L Grade B Geothermal Pipeline in Correlation with Corrosion under Insulation显示文摘 | Handoko Subawi Budi Lukman Hakim | 2014 | Journal of Energy and Power Engineering2014，8，12： | 0 |
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