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| 1 | Probiotic effects on intestinal fermentation patterns in patients with irritable bowel syndrome显示文摘AIM: To determine whether Lactobacillus casei strain Shirota (Yakult ) can alter small intestinal bacterial overgrowth (SIBO), as tested by the lactulose breath test, and whether this is associated with changes in symptoms in irritable bowel syndrome (IBS). METHODS: 18 patients with IBS (Rome Ⅱ criteria), who showed an early rise in breath hydrogen with lactulose (ERBHAL), consumed 65 mL of Yakult daily for 6 wk. Lactulose breath test was repeated at the end of the treatment period. Symptoms were recorded daily using a 10 cm visual analogue scale. RESULTS: 14 patients completed the study, 9 (64%) had reversal of ERBHAL, with the median time of f irst rise in breath hydrogen increasing from 45 to 75 min (P = 0.03). There was no signifi cant improvement in the symptom score with probiotic therapy, except for wind (P=0.04). Patients commencing with at least moderate symptoms and who no longer had ERBHAL at the end of treatment, showed improvement in the overall symptoms scores [median fi nal score 5.3 (IQR3.9-5.9), 55% reduction; n=6] to a greater extent than those who had had persisting ERBHAL [final score 6.9 (5.0-7.0), 12% reduction; n = 5; P = 0.18]. CONCLUSION: Yakult is effective in altering fermentation patterns in the small bowel, consistent with reducing SIBO. The loss of ERBHAL was associated with reduced symptoms. The true interpretation of these fi ndings awaits a randomised, controlled trial. | Jacqueline S Barrett Kim EK Canale Richard B Gearry Peter M Irving Peter R Gibson | 2008 | World Journal of Gastroenterology2008，14，32： | 16 |
| 2 | Antibacterial activity of various leaf extracts of Merremia emarginata显示文摘Objective:To investigate the antibacterial activity and phytochemical screening of the aqueous.methanol and petroleum ether leaf extracts of Merremia emarginata(M.emarginata).Methods:The antibavterial activity of leaf extracts of M.emarginata were evaluated by agar well diffusion method against four selected bacterial species.Results:The presence of tannins,flavonoids,amino acids,starch,glycosides and carbohydrates in the different leaf extracts was established.The methanol extract was more effective against Baciilus cereus and Eseherkhia coli,whereas aqueous extract was more effective against Staphylococcus aureus and Pseudomonas aeruginosa.Condusions:The results in the present study suggest that M.emarginata leaf can be used in treating diseases caused by the tested organisms. | EK Elumalai M Ramachandran T Thirumalai P Vinothkumar | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，5： | 8 |
| 3 | In Situ Etching for Total Control Over Axial and Radial Nanowire Growth显示文摘We report a method using in situ etching to decouple the axial from the radial nanowire growth pathway,independent of other growth parameters.Thereby a wide range of growth parameters can be explored to improve the nanowire properties without concern of tapering or excess structural defects formed during radial growth.We demonstrate the method using etching by HCl during InP nanowire growth.The improved crystal quality of etched nanowires is indicated by strongly enhanced photoluminescence as compared to reference nanowires obtained without etching. | Magnus T.Borgström Jesper Wallentin Johanna Trägårdh Peter Ramvall Martin Ek LReine Wallenberg Lars Samuelson Knut Deppert | 2010 | Nano Research2010，3，4： | 4 |
| 4 | Tensile and fracture properties of an Mg-RE-Zn alloy at elevated temperatures显示文摘Magnesium alloy EZ10(Mg-RE-Zn) was deformed in tension at temperatures from 20 up to 520 °C. A rapid decrease of the yield and tensile strength with temperature was observed at temperatures higher than 300 °C. On the other hand, ductility of samples rapidly increased in the same temperature range. Light microscopy and scanning electron microscopy was used to reveal the reason for these behaviours. Intermetallic particles in grain boundaries are responsible for excellent mechanical properties at lower temperatures. Diffusional processes occurring at temperatures higher than 300 °C significantly influenced the deformation mechanism as well as the fracture character. | TROJANOVZuzanka DONI Tibor LUK Pavel PALEK Peter CHALUPOV Mária TILLOV Eva BASTOVANSKY Ronald | 2014 | Journal of Rare Earths2014，32，6： | 3 |
| 5 | 顽固性高血压与由心内容积决定的血管内液体潴留无关显示文摘顽固性高血压(refractory hypertension,RfHTN)是一种极端的抗高血压治疗失败的表现形式,定义为使用了包括长效噻嗪类和盐皮质激素受体拮抗剂在内的≥5种药时血压仍控制欠佳。RfHTN是难治性高血压(resistant hypertension,RHTN)的一个亚组,RHTN定义为使用≥3种降压药(包括利尿剂)后血压仍〉135/85mm Hg(1mm Hg=0.133kPa)。 | 刘青 叶鹏 Velasco A Siddiqui M Kreps E Kolakalapudi P Dudenbostel T Arora G Judd EK Prabhu SD Lloyd SG Oparil S Calhoun DA | 2018 | 中华高血压杂志2018，26，7： | 2 |
| 6 | Preoperative acute hype-rvolemic hemodilution with hyolroxyethylstarch:an alternative to acute normovolemic hemodilution显示文摘 | Mielke LL Entholzner EK Kling M | 1997 | Anesth Analg1997，84，： | 1 |
| 7 | Protection from postconditianing depends on the number of short ischemic insults in anesthetized pigs 显示文摘 | ILIODROMITIS EK GEORGIADIS M COHEN MV | 2006 | Basic Res Cardiol2006，101，： | 1 |
| 8 | Hypoxic pulmonary vasoconstriction is modulated by P - 450 metabolites 显示文摘 | Zhu D Birk EK Parviz M | 2000 | Am J Physiol2000，279，4： | 1 |
| 9 | Renalase plasma levels areassociated with systolic blood pressure in patients with resistanthypertension显示文摘 | Schlaich M Socra tous F Ekelis N | 2010 | J Hypertens2010，28，： | 1 |
| 10 | Management of thyroid dysfunction during pregnancy and postpartum : an Endo- crine Society clinical practice guideline 显示文摘 | De Groot L Abalovich M Alexander EK | 2012 | J Clin Endocrinol Metab2012，97，8： | 1 |
| 11 | Progress in the use of adeno-associated viral vectors for gene therapy显示文摘 | Buning H Braun Falco M Hal ek M | | 0，，03： | 1 |
| 12 | Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling显示文摘 | Nahid MA Satoh M Chan EK | | 0，，： | 1 |
| 13 | A functional phylogenomic view of the seed plants显示文摘 | Lee EK Cibrian-Jaramillo A Kolokotronis SO Katari MS Stamatakis A Ott M Chiu JC Little DP Stevenson DW McCombie WR | | 0，，： | 1 |
| 14 | Modification of the Dittmer-Lester reagent for the detection of phospholipid derivatives on thin-layer chromatograms显示文摘 | Ryu EK Maccoss M | | 0，，4： | 1 |
| 15 | 'Smal stem cells'in adult tissues:very smal embryonic-like stem cells stand up显示文摘 | Zuba-Surma EK Kucia M Ratajczak J | | 0，，01： | 1 |
| 16 | Enteral nutritional support in prevention and treatment of pressure ulcers : a systematic review and recta-analysis显示文摘 | Stratton RJ Ek AC Engfer M | 2005 | Ageing Res Rev2005，4，42： | 1 |
| 17 | Activation of vagal afferents after intravenous injection of interleukin-lB: Role of endogenous prostaglandins显示文摘 | Ek M Kurosawa M Lundeberg T | 1998 | Neurosci1998，18，22： | 1 |
| 18 | Bacterial communityvariation in human body habitats across space and time显示文摘 | Costello EK Lauber CL Hamady M | 2009 | Science2009，326，5960： | 1 |
| 19 | Behavior of different monocomponent endoglucanases on the accessibility and reactivity of dissolving-grade pulps for viscose process 显示文摘 | lbarra D K~ pcke V Ek M | 2010 | Enzyme and Microbial Technology2010，47，7： | 1 |
| 20 | Oxalic acid formation during ECF and TCF bleaching of kraft pulp显示文摘 | Elsander A Ek M Gellerstedt G | 2000 | Tappi Journal2000，83，2： | 1 |
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