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| 1 | Continuous wound infusion of local anaesthetic agents following colorectal surgery:Systematic review and meta-analysis显示文摘AIM:To provide a specifi c review and meta-analysis of the available evidence for continuous wound infusion of local anaesthetic agents following midline laparoto-my for major colorectal surgery. METHODS: Medline, Embase, trial registries, conference proceedings and article reference lists were searched to identify randomised, controlled trials of continuous wound infusion of local anaesthetic agents following colorectal surgery. The primary outcomes were opioid consumption, pain visual analogue scores (VASs), return to bowel function and length of hospital stay. Weighted mean difference were calculated for continuous outcomes. RESULTS: Five trials containing 542 laparotomy wounds were eligible for inclusion. There was a sig- nificant decrease in post-operative pain VAS at rest on day 3 (weighted mean difference: -0.43; 95% CI: -0.81 to -0.04; P = 0.03) but not on post-operative day 1 and 2. Local anaesthetic infusion was associated with a signifi cant reduction in pain VAS on movement on all three post-operative days (day 1 weighted mean difference: -1.14; 95% CI: -2.24 to -0.041; P = 0.04, day 2 weighted mean difference: -0.97, 95% CI: -1.91to -0.029; P = 0.04, day 3 weighted mean difference: -0.61; 95% CI: 1.01 to -0.20; P = 0.0038). Local an- aesthetic wound infusion was associated with a signifi - cant decrease in total opioid consumption (weighted mean difference: -40.13; 95% CI: -76.74 to -3.53; P = 0.03). There was no signifi cant decrease in length of stay (weighted mean difference: -20.87; 95% CI: -46.96 to 5.21; P = 0.12) or return of bowel function (weighted mean difference: -9.40; 95% CI: -33.98 to 15.17; P = 0.45). CONCLUSION: The results of this systematic re- view and meta-analysis suggest that local anaesthetic wound infusion following laparotomy for major color- ectal surgery is a promising technique but do not pro- vide conclusive evidence of benefi t. Further research is required including cost-effectiveness analysis. | Alan Karthikesalingam Stewart R Walsh Sheraz R Markar Umar Sadat Tjun Y Tang Charles M Malata | 2008 | World Journal of Gastroenterology2008，14，34： | 4 |
| 2 | Analysis of the ferroelectric phase transition in BaAl2O4 by group theoretical methods and first-principles calculations 显示文摘 | Stokes H T Sadate C Hatch D M | 2002 | Phys Rev B2002，65，06： | 2 |
| 3 | Effect of peri- odontal disease on preeclampsia显示文摘 | F Sayar M Sadat Hoseini S Abbaspour | 2011 | Iranian journal of pub- lic health2011，40，3： | 1 |
| 4 | Effect of ginger on relieving nausea and vomiting in pregnancy: a randomized, placebo - controlled trial显示文摘 | Saberi F Sadat Z Abedzadeh - Kalahroudi M | 2014 | Nurs Midwifery Stud2014，3，1： | 1 |
| 5 | Circumvention of 5-fluorouracil resistance in human stomach cancer cells by uracil phosphoribosyltransferase gane transduction显示文摘 | Inaba M Swada H Sadate A | 1999 | Jpn J Cancer Res1999，90，3： | 1 |
| 6 | Risk factors of recurrent lumbar disk herniation显示文摘 | Shimia M Babaei -Ghazani A Sadat BE | 2013 | Asian J Neurosurg2013，8，2： | 1 |
| 7 | Prediction of crop production using drought indices at different time scales and climatic factors to manage drought risk显示文摘 | Sadat Noori S M Liaghat A M Ebrahimi K | 2012 | J Am Water Resour As2012，48，1： | 1 |
| 8 | Management of the left subclavian artery during endovascular repair of the thoracic aorta显示文摘 | Noor N Sadat M Hayes PD | 2008 | J Endovasc Ther2008，15，2： | 1 |
| 9 | Risk factors of recurrent lumbar disk herniation显示文摘 | Shimia M Babaei-Ghazani A Sadat BE | 2013 | Asian J Neurosurg2013，8，2： | 1 |
| 10 | Recycling of PVC waste显示文摘 | Sadat S M Bakhshandeh G R | 2011 | Polymer Degradation and Stability2011，96，4： | 1 |
| 11 | Synthesis methods for nanosized hydroxyapatite with diverse structures 显示文摘 | SADAT - SHOJAI M KHORASANI M T DINPANAH - KHOSHDARGI E | 2013 | Acta Bio- mater2013，9，8： | 1 |
| 12 | Risk factors of recurrent lumbar disk hernialion显示文摘 | Shimia M Babaei-Ghazani A Sadat BE | 2013 | Asian J Neurosurg2013，8，2： | 1 |
| 13 | Dipole-interaction mediated hyperthermia heating mechanism of nanostructured Fe3 04 composites显示文摘 | SADAT M E RONAK P BUD'KO S L | 2014 | Materials Letters2014，129，： | 1 |
| 14 | Medullary and papillary carcino- ma of the thyroid gland occurring as a collision tumor with lymph node metastasis: A case report 显示文摘 | Sadat Alavi M Azarpira N | 2011 | Med Case Rep2011，5，1： | 1 |
| 15 | prtH2,Not prtH, is the ubiquitous cell wall proteinase gene in Lactobacillus helveticus显示文摘 | Genay M Sadat L Gagnaire V | 2009 | Applied and Environmental Microbiology2009，75，10： | 1 |
| 16 | A comparative 6-month clinical study of acellular dermal matrix allograft and subepithelial connective tissue graft for root coverage显示文摘 | Sadat Mansouri S Ayoubian N Eslami Manouehehri M | 2010 | J Dent (Tehran)2010，7，3： | 1 |
| 17 | The effect of acupressure on quality of sleep in Iranian elderly nursing home residents显示文摘 | Reza H Kian N Pouresmail Z Masood K Sadat Seyed Bagher M Cheraghi MA | | 0，，： | 1 |
| 18 | Management of the left subclavian artery during endovascular repair of the thoracic aorta显示文摘 | Noor N Sadat M Hayes PD | 2008 | J Endovasc Ther2008，15，2： | 1 |
| 19 | Risk factors of recurrent lumbar disk herniation显示文摘 | Shimia M Babaei-Ghazani A Sadat BE | 2013 | Asian J Neurosurg2013，8，2： | 1 |
| 20 | Effect of mode of delivery on postpartum depression in Iranian women 显示文摘 | Sadat Z Kafaei Atrian M Masoudi Alavi N | 2014 | J Obstet Gynaecol Res2014，40，1： | 1 |
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