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| 1 | case for cost-plus contracting显示文摘 | F.H.Griffs Frde M.Butler | | 0，，： | 1 |
| 2 | Lipogenic effects of androgen signaling in normal and malignant prostate显示文摘Prostate cancer is an androgen-dependent cancer with unique metabolic features compared to many other solid tumors,and typically does not exhibit the“Warburg effect”.During malignant transformation,an early metabolic switch diverts the dependence of normal prostate cells on aerobic glycolysis for the synthesis of and secretion of citrate towards a more energetically favorable metabolic phenotype,whereby citrate is actively oxidised for energy and biosynthetic processes(i.e.de novo lipogenesis).It is now clear that lipid metabolism is one of the key androgen-regulated processes in prostate cells and alterations in lipid metabolism are a hallmark of prostate cancer,whereby increased de novo lipogenesis accompanied by overexpression of lipid metabolic genes are characteristic of primary and advanced disease.Despite recent advances in our understanding of altered lipid metabolism in prostate tumorigenesis and cancer progression,the intermediary metabolism of the normal prostate and its relationship to androgen signaling remains poorly understood.In this review,we discuss the fundamental metabolic relationships that are distinctive in normal versus malignant prostate tissues,and the role of androgens in the regulation of lipid metabolism at different stages of prostate tumorigenesis. | Chui Yan Mah Zeyad D.Nassar Johannes V.Swinnen Lisa M.Butler | 2020 | Asian Journal of Urology2020，7，3： | 1 |
| 3 | Spider odors induce stoichiometric changes in fruit fly Drosophila melanogaster显示文摘Animal senses and signals are amazingly diverse,and the major modalities by which animals acquire sensory input from their environments are sound,light,vibration,and chemical signals.Insects mainly rely on visual,nociceptive,and olfactory cues to discriminate between rewards and risks.It has been shown that the visual and olfactory cues of predators substantially affect the adult phenotype in Drosophila melanogaster(Krams et al.2016),a prominent animal model for biological research. | Ronalds KRAMS Tatjana KRAMA Maris MUNKEVICS Sarah EICHLER David M.BUTLER Linda DOBKEVICA Priit JOERS Jorge CONTRERAS-GARDUNO Janina DAUKSTE Indrikis A.KRAMS | 2021 | Current Zoology2021，67，1： | 0 |
| 4 | Religious Fundamentalism,Right-Wing Authoritarianism,and the LGBTQ Community显示文摘According to the advocacy group Parents,Families,and Friends of Lesbians and Gays(PFLAG),gays and lesbians are victims of hate crimes seven times as often as straight peers.The question becomes what underlying ideology currently exists in American society to perpetuate this behavior?This paper explores the impact of conservatism and religious ideology to anti-gay prejudice in public schools.The paper presents a model of an intergroup program using prevention of harassment,bullying and rejection to gay members of the student body by attempting a change in attitudes regarding gay students.It also provides recommendations for school administrators and teachers for confronting these challenges in public education. | Barbara M.Butler Christopher Butler | 2019 | International Relations and Diplomacy2019，7，1： | 0 |
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