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| 1 | Leptin, cardiovascular diseases and type 2 diabetes mellitus显示文摘Leptin,经由胃口抑制在食物吸入的控制被含有的 adipokine,可以也刺激氧化应力,发炎,血栓,动脉的僵硬, angiogenesis 和 atherogenesis。这些导致 leptin 的效果可以预先安排到心血管的疾病的发展。在现在的评论,我们讨论与两个的存在,严厉或预后连接 leptin 层次的证据冠的动脉疾病和非心脏的脉管的疾病象中风那样,颈动脉动脉疾病,外部动脉疾病(垫)和象与长期的肾疾病( CKD )和类型一样的腹的大动脉的动脉瘤( AAA ) 2 糖尿病 mellitus ( T2DM )。Leptin 层次断然与存在,严厉,程度和冠的动脉粥样硬化以及与存在,严厉和 ischemic 和出血性的击的差的临床的结果的损害复杂性被联系了。但是冲突结果也存在。而且, leptin 被报导独立地预言普通颈动脉 intima 媒介厚度和颈动脉匾不稳定性。在 hyperleptinemia 和垫之间的一个连接被报导了,而有限数据在在 leptin 和 AAA 之间的潜在的协会上是可得到的。提高的 leptin 集中也象与胰岛素抵抗一样与 CKD 发生和前进有关, T2DM,微 -- 并且 macrovascular 糖尿病患者复杂并发症。Statins 和 antidiabetic 药(包括的 sitagliptin, metformin, pioglitazone, liraglutide 和 empagliflozin ) 可以影响 leptin 层次。进一步的研究被需要建立潜在的使用(如果任何) 是的 leptin 在这些疾病的一个治疗学的目标。 | Niki KATSIKI Dimitri P MIKHAILIDIS Maciej BANACH | 2018 | Acta Pharmacologica Sinica2018,39,7: | 41 |
| 2 | Screening for scoliosis-New recommendations,old dilemmas,no straight solutions显示文摘This opinion review considers the prevailing question of whether to screen or notto screen for adolescent idiopathic scoliosis. New and improved standards ofpeople-oriented care and person-centredness, as well as improved principles ofpreventive screening and guideline development, have been postulated andimplemented in health care systems and cultures. Recommendations addressingscreening for scoliosis differ substantially, in terms of their content, standards ofdevelopment and screening principles. Some countries have discontinued issuingrecommendations. In the last decade, a number of updated and newrecommendations and statements have been released. Systematically developedguidelines and recommendations are confronted by consensus and opinion-basedstatements. The dilemmas and discrepancies prevail. The arguments concentrateon the issues of the need for early detection through screening in terms of theeffectiveness of early treatment, on costs and cost-effectiveness issues, scientificand epidemiologic value of screenings, and the credibility of the sources ofevidence. The problem matter is of global scale and applies to millions of people.It regards clinical and methodological dilemmas, but also the matter of vulnerableand fragile time of adolescence and, more generally, children’s rights. Thedecisions need to integrate people’s values and preferences – screening tests needto be acceptable to the population, and treatments need to be acceptable forpatients. Therefore we present one more crucial, but underrepresented in thediscussion, issue of understanding and implementation of the contemporaryprinciples of person-centred care, standards of preventive screening, andguideline development, in the context of screening for scoliosis. | Maciej Płaszewski Weronika Grantham Ejgil Jespersen | 2020 | World Journal of Orthopedics2020,11,9: | 3 |
| 3 | Biocompatible and biodegradable ullzafine fibrillar scaffold materials for tissue engineering by facile grafting of L-lactide onto chitosan显示文摘 | Maciej S Alexei P L Gustavo L et ai | 2008 | Biomacromolecules2008,9,7: | 1 |
| 4 | Biocompatible and biodegradable ultrafine fibrillar scaffold materials for tissue engineering by facile grafting of L-lactide onto chitosan显示文摘 | Maciej Skotak Aiexei P Leonov Gustavo Larson | 2008 | Biomacromolecules2008,9,7: | 1 |
| 5 | 1H, 13C NMRstudies and GIAO/DFT calculations of substituted N-(4-aryl-1-piperazinyl- butyl)derivatives, new analogues of buspirone显示文摘 | MACIEJ P JERZY K MIROSLAW P | 2004 | J Mol Struct2004,698,123: | 1 |
| 6 | Inverse analysis for identification of rheological and friction models in metal forming显示文摘 | Danuta S Jerzy G Maciej P | 2006 | Computer Methods in Applied Mechanics and Engineering2006,195,48: | 1 |
| 7 | Content of blood cell components,inflammatory cytokines and growth factors in autologous platelet-rich plasma obtained by various methods显示文摘BACKGROUND The evaluation of the efficacy of platelet-rich plasma(PRP) in clinical practice yields conflicting results and raises numerous controversies. This may be due to different concentrations of biologically active components in PRP obtained with the use of different methods of gravity separation.AIM To compare the content, repeatability and correlations between biologically active components in PRP obtained with four different commercial systems.METHODS From a whole blood sample of each of 12 healthy male volunteers, 4 PRP samples were prepared using 4 different commercial kits [Arthrex Autologous Conditioned Plasma(ACP), Mini GPS Ⅲ, Xerthra, Dr. PRP] in accordance with the instructions provided by the manufacturers. A comparative analysis of blood cell components-13 selected inflammatory cytokines and 7 growth factors-in the obtained PRP samples was performed using the Kruskal-Wallis test by ranks. The repeatability of results in each method was evaluated by the estimation of the coefficient of variation. The Spearman correlation was used to estimate the relationship between blood cell content and cytokines.RESULTS Significantly higher concentrations of platelets(PLT), white blood cells(WBC) and red blood cells(RBC) were found in PRP obtained with the use of Mini GPS Ⅲ than in PRP obtained using other systems. Significant differences in the content of growth factors and cytokines in PRP were found. A positive correlation of the amount of PLT, RBC and WBC with the concentration of most of the growth factors was found but in only three inflammatory cytokines. The obtained correlations between blood cell components and cytokines differed between the systems in terms of statistical significance, which may be due to insufficient sample size. The repeatability of the obtained PLT concentration also varied between protocols with the lowest in Xerthra and the highest in Arthrex ACP.CONCLUSION Significant differences in the content of biologically active components and their repeatability were found in PRP obtained by various methods, providing new data for further research. | Maciej Dejnek Jarosław Witkowski Helena Moreira Sylwia Płaczkowska Piotr Morasiewicz PawełReichert Aleksandra Królikowska | 2022 | World Journal of Orthopedics2022,13,6: | 1 |
| 8 | A new polyurethane binder providing high green strength of dry-pressed alumina显示文摘 | MAREK P MACIEJ H MARIUSZ O | 2003 | Ceram Int2003,29,: | 1 |
| 9 | Generation and propagation of transient nonlinear waves in a wave flume显示文摘 | WOJCIECH S MACIEJ P | 2008 | Coastal Engineering2008,55,: | 1 |
| 10 | Laparoscopic splenectomy in children-A multicenter experience显示文摘 | Maciej M Dariusz P Wojciech K | 2008 | J Pediatr Surg2008,43,5: | 1 |
| 11 | Effect of Rumen-protected Amino Aids (L-lysine and DL-methionine ) on Processing Quality of Milk显示文摘 | TADEUSZ G P PISULEWSKI Z MACIEJ K | 1999 | Polish Journal of Food and Nutrition Sciences1999,849,3: | 1 |
| 12 | Benign paroxysmal vertigo of childhood显示文摘 | JOZEF M MACIEJ P KRZYSZTOF D | 2007 | Otolaryngol2007,61,: | 1 |
| 13 | Deletion and insert Operations in voronoi/delaunay methods and applications显示文摘 | Mostafavi M A Gold C P Maciej Dakowicz | 2003 | Computers & Geosciences2003,23,4: | 1 |
| 14 | Thyroid hormone and their receptors in the regulation of cell proliferation 显示文摘 | Monika PK Maciej P Olga T | 2006 | Acta Biochimica Polonica2006,53,4: | 1 |
| 15 | Role for Calcium in the Development of Ovarial Patency in Heliothis virescens 显示文摘 | Maciej A P Emily O Crystal R | 2008 | J Insect Physiol2008,54,2: | 1 |
| 16 | The role of laparoscopy in abdominal trauma - review of the literature 显示文摘 | Maciej W Krystyn S Jerzy P | 2011 | Wideochir Inne Tech Malo Inwazyjne2011,6,3: | 1 |
| 17 | Distinct clinical outcomes for cytogenetic abnormalities evolving from aplastic anemia显示文摘 | MACIEJ EWSKI J P RISITANO A SLOAND E M | 2002 | Blood2002,99,: | 1 |
| 18 | Utilizing Statistical Residual Life Estimates of Bearing to Quantify the Influence of Preventive Maintenance Actions显示文摘 | Volk P J Maciej W Maciej Z | | 0,,04: | 1 |
| 19 | 1H,13C NMR studies and GIAO/DFT calculations of substituted N-(4-aryl-1-piperazinylbutyl)derivatives,new analogues of buspirone显示文摘 | MACIEJ P JERZY K MIROSLAW P | 2004 | J Mol Struct2004,698,13: | 1 |
| 20 | Boundary Layer Transition on the High Lift T106A Low-Pressure Turbine Blade with an Oscillating Down- stream Pressure Field 显示文摘 | Maciej M Opoka Richard L Thomas Howard P Hod- son | 2008 | ASME Journal of Turboma- chinery2008,130,2: | 1 |