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| 1 | Capsule endoscopy:Present status and future expectation显示文摘Video capsule endoscopy(CE)since its introduction 13years back,has revolutionized our approach to small intestinal diseases.Obscure gastrointestinal bleed(OGIB)continues to be the most important indication for CE with a high sensitivity,specificity as well as positive and negative predictive values.It is best performed during ongoing bleed or immediately thereafter.Overt OGIB has a higher diagnostic yield than occult OGIB.However,even in iron deficiency anemia,CE is emerging as important investigation after initial negative work up.In suspected Crohn’s disease(CD),CE has been shown superior to traditional imaging and endoscopic technique and should be considered after a negative ileocolonoscopy.Although CE has also been used for evaluating established CD,a high capsule retention rate precludes its use ahead of cross-sectional imaging.Celiac disease,particularly where gastro-duodenoscopy cannot be performed or is normal,can also be investigated by CE.Small bowel tumor,hereditary polyposis syndrome,and non-steroidal anti-inflammatory drugs induced intestinal damage are other indications for CE.Capsule retention is the only significant adverse outcome of CE and occurs mostly in presence of intestinal obstruction.This can be prevented by use of Patency capsule prior to CE examination.Presence of cardiac pacemaker and intracardiac devices continue to be relative contraindications for CE,though data do not suggest interference of CE with these devices.Major limitations of CE today include failure to control its movement from outside,inability of CE to acquire tissue for diagnosis,and lack of therapeutic help.With ongoing interesting and exciting developments taking place in these areas,these issues would be solved in all probability in near future.CE has the potential to become one of the most important tools in diagnostic and possibly in the therapeutic field of gastrointestinal disorder. | Mahesh K Goenka Shounak Majumder Usha Goenka | 2014 | World Journal of Gastroenterology2014，20，29： | 9 |
| 2 | Surgical left atrial appendage occlusion during cardiac surgery: A systematic review and meta-analysis显示文摘AIM To evaluate the safety and efficacy of surgical left atrial appendage occlusion(s-LAAO) during concomitant cardiac surgery.METHODS We performed a comprehensive literature search through May 31 st 2018 for all eligible studies comparing s-LAAO vs no occlusion in patients undergoing cardiac surgery. Clinical outcomes during follow-up included: embolic events, stroke, all-cause mortality, atrial fibrillation(AF), reoperation for bleeding and postoperative complications. We further stratified the analysis based on propensity matched studies and AF predominance.RESULTS Twelve studies(n = 40107) met the inclusion criteria.s-LAAO was associated with lower risk of embolic events(OR: 0.63, 95%CI: 0.53-0.76; P < 0.001) and stroke(OR: 0.68, 95%CI: 0.57-0.82; P < 0.0001).Stratified analysis demonstrated this association was more prominent in the AF predominant strata. There was no significant difference in the incidence risk of allcause mortality, AF, and reoperation for bleeding and postoperative complications.CONCLUSION Concomitant s-LAAO during cardiac surgery was associated with lower risk of follow-up thromboembolic events and stroke, especially in those with AF without significant increase in adverse events. Further randomized trials to evaluate long-term benefits of s-LAAO are warranted. | Varunsiri Atti Mahesh Anantha-Narayanan Mohit K Turagam Scott Koerber Sunil Rao Juan FViles-Gonzalez Rakesh MSuri Poonam Velagapudi Dhanunjaya Lakkireddy David G Benditt | 2018 | World Journal of Cardiology2018，10，11： | 2 |
| 3 | Ferroelectricity in a pure BiFeO3 ceramic 显示文摘 | MAHESH K M PALKARA V R SRINIVAS K | 2000 | Appl Phys Lett2000，76，19： | 1 |
| 4 | Analysis of numerical errors in large eddy simulation using statistical closure theory显示文摘 | Park N Mahesh K | 2007 | Journal of Computational Physics2007，222，1： | 1 |
| 5 | Evidence that neu- ronal nitric oxide synthase but not heine oxygenase increases in the hypothalamus on proestrus afternoon显示文摘 | Lamar C A Bhat G K Mahesh V B | 1999 | Neuroendocrinology1999，70，5： | 1 |
| 6 | Extended indications for enteral nutritional support显示文摘 | Mahesh C Sriram K Lakshmiprabha V | | 0，，02： | 1 |
| 7 | Effect of mineral phosphates on growth and nitrogen fixation of diazotro- phie eyanobaeteria Anabaena variabilis and Westiellopsis prolifica 显示文摘 | Mahesh S Yandigeri Arvind K Yadav K K M | 2010 | Antonie van Leeuwenhoek2010，，97： | 1 |
| 8 | Direct numerical simulation: a tool in turbulence research 显示文摘 | Moin P Mahesh K | 1998 | Annual Review of Fluid Mechanics1998，30，： | 1 |
| 9 | Modeling of droplet dynamic and thermal behavior during spray deposition 显示文摘 | MAHESH N S MENDONCA J MURALIDHARA M K | 2003 | Indian Academy of Sciences2003，26，3： | 1 |
| 10 | Modeling of droplet dynamic and thermal behavior during spray deposition 显示文摘 | Mendonca Johnson Mahesh N S Muralidhara M K | 2003 | Mater Science Bull2003，26，3： | 1 |
| 11 | Ethanol production from glucose and xylose by immobilized Zymomonas mobilis CP4显示文摘 | MAHESH S K MARIA B CHRISTOPHER K S | 2000 | Applied Biochemistry and Biotechnology2000，8486，： | 1 |
| 12 | Zirconium(IV)chloride catalyzed one-pot sunthesis of3 , 4-dihudropyrimidin-2- (1H )-ones 显示文摘 | REDDY C V MAHESH M RAJU P V K | 2002 | TetrahedronLett2002，43，14： | 1 |
| 13 | A novel 5-HT (2A) receptor antagonist exhibits antidepressant- like effects in a battery of rodent behavioural assays: approaching early-onset antidepressants显示文摘 | Pandey D K Mahesh R Kumar A A | 2010 | Pharmacol Biochem Behav2010，94，3： | 1 |
| 14 | A numerical method for large eddy simulations in complex geometries 显示文摘 | Mahesh K Constantinescu G Moin P | 2004 | Journal of Computational Physics2004，197，： | 1 |
| 15 | Dilatometric study of martensitic transformation in NiTiCu and NiTi shape memory alloys 显示文摘 | Uchil J Mahesh K K Kumara K G | 2001 | Journal of Materials Science2001，36，： | 1 |
| 16 | Ferroelectricity in a pure BiFeO3 ceramic显示文摘 | Mahesh Kumar M Palkar V R Srinivas K | 2000 | Appl Phys Lett2000，76，19： | 1 |
| 17 | Urbanization and Its Im- pact on Groundwater: A Remote Sensing and GIS-based Assess- ment Approach显示文摘 | Mahesh K J Deepak K Garg P K | 2009 | Environmentalist2009，29，1： | 1 |
| 18 | Thermomechanical behavior of Ti-rich NiTi shape memory alloys 显示文摘 | Paula A S Mahesh K K Dos Santos C M L | 2007 | Materials Science and EngineeringA2007，，2： | 1 |
| 19 | Direct numerical simulation: a tool in turbulence research显示文摘 | Moin P Mahesh K | 1998 | Annual Review of Fluid Mechan- ics1998，30，： | 1 |
| 20 | Mechanical, Thermal and Morphological Behavior of Bismaleimide Modified Polyu- rethane-epoxy IPN Matrices显示文摘 | Mahesh K P O Alagar M K umar A | 2003 | Polymers for Advanced Techologies2003，14，： | 1 |
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