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| 1 | Reversibility of minimal hepatic encephalopathy following liver transplantation in Egyptian cirrhotic patients显示文摘AIM To evaluate the reversibility of minimal hepatic encephalopathy(MHE) following liver transplantation(LT) in Egyptian cirrhotic patients. METHODS This prospective study included twenty patients with biopsy-proven liver cirrhosis listed for LT and twenty ageand sex-matched healthy control subjects. All underwent neuro-psychiatric examination, laboratory investigations, radiological studies and psychometric tests including trail making test A(TMT A), TMT B, digit symbol test and serial dotting test. The psychometric hepatic encephalopathy score(PHES) was calculated for patients to diagnose MHE. Psychometric tests were repeated six months following LT in the cirrhotic patient group. RESULTS Before LT, psychometric tests showed highly significant deficits in cirrhotic patients in comparison to controls(P < 0.001). There was a statistically significant improvement in test values in the patient group after LT; however, their values were still significantly worse than those of the controls(P < 0.001). The PHES detected MHE in 16 patients(80%) before LT with a median value of -7 ± 3.5. The median PHES value was significantly improved following LT, reaching-4.5 ± 5(P < 0.001), and the number of patients with MHE decreased to 11(55%). The pre-transplant model for end-stage liver disease(MELD) score ≥ 15 was significantly related to the presence of post-transplant MHE(P = 0.005). More patients in whom reversal of MHE was observed had a pre-transplant MELD score < 15.CONCLUSION Reversal of MHE in cirrhotic patients could be achieved by LT, especially in those with a MELD score < 15. | Mahmoud A Osman Moataz M Sayed Khaled A Mansour Shereen A Saleh Wesam A Ibrahim Sara M Abdelhakam Mohamed Bahaa Wael A Yousry Hosam S Elbaz Reginia N Mikhail Azza M Hassan Ehab H Elsayed Dalia A Mahmoud | 2016 | World Journal of Hepatology2016，8，30： | 11 |
| 2 | Investigation of soliton solutions with different wave structures to the(2+1)-dimensional Heisenberg ferromagnetic spin chain equation显示文摘The principal objective of this article is to construct new and further exact soliton solutions of the(2+1)-dimensional Heisenberg ferromagnetic spin chain equation which investigates the nonlinear dynamics of magnets and explains their ordering in ferromagnetic materials.These solutions are exerted via the new extended FAN sub-equation method.We successfully obtain dark,bright,combined bright-dark,combined dark-singular,periodic,periodic singular,and elliptic wave solutions to this equation which are interesting classes of nonlinear excitation presenting spin dynamics in classical and semi-classical continuum Heisenberg systems.3D figures are illustrated under an appropriate selection of parameters.The applied technique is suitable to be used in gaining the exact solutions of most nonlinear partial/fractional differential equations which appear in complex phenomena. | M S Osman K U Tariq Ahmet Bekir A Elmoasry Nasser S Elazab M Younis Mahmoud Abdel-Aty | 2020 | Communications in Theoretical Physics2020，72，3： | 4 |
| 3 | Do age-associated changes of voltage-gated sodium channel isoforms expressed in the mammalian heart predispose the elderly to atrial fibrillation?显示文摘Atrial fibrillation(AF)is the most common cardiac arrhythmia worldwide.The prevalence of the disease increases with age,strongly implying an age-related process underlying the pathology.At a time when people are living longer than ever before,an exponential increase in disease prevalence is predicted worldwide.Hence unraveling the underlying mechanics of the disease is paramount for the development of innovative treatment and prevention strategies.The role of voltage-gated sodium channels is fundamental in cardiac electrophysiology and may provide novel insights into the arrhythmogenesis of AF.Na_v1.5 is the predominant cardiac isoform,responsible for the action potential upstroke.Recent studies have demonstrated that Na_v1.8(an isoform predominantly expressed within the peripheral nervous system)is responsible for cellular arrhythmogenesis through the enhancement of pro-arrhythmogenic currents.Animal studies have shown a decline in Na_v1.5 leading to a diminished action potential upstroke during phase 0.Furthermore,the study of human tissue demonstrates an inverse expression of sodium channel isoforms;reduction of Na_v1.5 and increase of Na_v1.8 in both heart failure and ventricular hypertrophy.This strongly suggests that the expression of voltage-gated sodium channels play a crucial role in the development of arrhythmias in the diseased heart.Targeting aberrant sodium currents has led to novel therapeutic approaches in tackling AF and continues to be an area of emerging research.This review will explore how voltage-gated sodium channels may predispose the elderly heart to AF through the examination of laboratory and clinical based evidence. | Emmanuel Isaac Stephanie M Cooper Sandra A Jones Mahmoud Loubani | 2020 | World Journal of Cardiology2020，12，4： | 3 |
| 4 | Immunization against Egyptian Schistosoma mansoni infection by multivalent DNA vaccine显示文摘由几抗原组成的多价的疫苗的发展是对不同寄生虫紧张和寄生虫生命周期阶段创造宽广范围的保护的一条新奇途径。我们以前证实了血吸虫 Sm21.7 和 Sm Fimbrin (SmFim ) 蛋白质能在老鼠导致保护。因此,这研究试图构造多价的 DNA 疫苗的 Sm21.7-SmFim/pBudCE4.1 并且评估它的有免疫力的功效。二血吸虫 mansoni 基因, Sm21.7 和 SmFim 的开的读物框架,被插入到为独立人士设计的真核细胞的表示原生质标志 pBudCE4.1 在哺乳动物的房间的二基因的表示。评估在里面在老鼠的多价的 Sm21.7-SmFim/pBudCE4.1 DNA 疫苗和它的免疫学的效果的 vitro 表示, recombinant 原生质标志 Sm21.7-SmFim/pBudCE4.1 习惯于 mRNA 的 transfect 293T 房间,和表示,蛋白质用反向的抄写聚合酶链反应和蛋白质印迹分析被检验。然后 Sm21.7-SmFim/pBudCE4.1 到的能力免于 S。mansoni 挑战感染在老鼠的种痘以后根据蠕虫负担和鸡蛋减小率被分析。种牛痘的老鼠出现了保护(56%) 的重要水平,和在数字和尺寸的减少,和在细胞的侧面的变化, granulomas。分别地,在肝和肠的鸡蛋减小是 41.53% 和 55.63% 相对仅仅收到了空向量的老鼠同样坚定。除了在蠕虫生存能力的减小,蠕虫肥沃和鸡蛋孵化能力被观察在使免疫的组跟随挑战感染。结果证明 Sm21.7-SmFim/pBudCE4.1 能表示 Sm2 1.7 和 SmFim mRNA 和蛋白质。连接酶的免疫吸着剂试金和蛋白质印迹分析显示使免疫的老鼠对 Sm21.7-SmFim/pBudCE4.1 产生了特定的免疫球蛋白 G。这些结果与多价的 S 建议那种痘。mansoni DNA 疫苗(SmFim-Sm21.7/pBudCE4.1 ) 不仅在蠕虫和卵负担导致重要减小,而且显著地减少卵 granulomas 的尺寸。在摘要,多价的疫苗与保护的重要水平刺激了特定的免疫并且反病理学的效果。 | Mahmoud H Romeih Hanem M Hassan Tarek S Abou Shousha Mohamed A Saber | 2008 | Acta Biochimica et Biophysica Sinica2008，40，4： | 3 |
| 5 | HepG2 cells support viral replication and gene expression of hepatitis C virus genotype 4 in vitro显示文摘瞄准:与丙肝的长期的复制建立一个房间文化系统病毒(HCV ) 染色体和病毒的抗原的表示在试管内。方法:HepG2 房间线被孵化与长期的丙肝从一个病人与浆液为它的危险性测试到 HCV。房间和上层清液在文化期间在各种各样的时间点被收获。文化上层清液为它感染天真的房间的能力被测试。存在减(反感觉) 在房间的核心和 E1 抗原的 RNA 海滨,和察觉被 RT-PCR 和免疫学的技术(流动血细胞计数和西方的污点) 分别地检验。结果:细胞内部的 HCV RNA 首先在 d 上被检测 3 在感染以后然后能一致地在至少三个月的一个时期上在房间和上层清液被检测。新鲜房间能从有教养的感染的房间感染上层清液。流动 cytometric 分析证明表面和在房子里使用的细胞内部的 HCV 抗原表示使 polyclonal 成为了抗体(反核心,和 anti-E1 ) 。西方的污点分析证明在分子量的产生免疫性的肽的簇的表示在一个月内在 31 和 45 kDa 之间延长了感染的房间的旧文化而这簇在 uninfected HepG2 房间是无法发现的。结论:HepG2 房间线产生 HCV 感染而且支持它的复制在试管内不仅。HCV 结构的蛋白质的表示能在感染的 HepG2 房间被检测。这些房间也能够流病毒的粒子进接着对 uninfected 房间变得传染的培养基。 | Mostafa K El-Awady Ashraf A Tabll Yasmine S El-Abd Mahmoud M Bahgat Hussein A Shoeb Samar S Youssef Noha G Bader El Din El-Rashdy M Redwan Maha El-Demellawy Moataza H Omran Wael T El-Garf Said A Goueli | 2006 | World Journal of Gastroenterology2006，12，30： | 2 |
| 6 | MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca^sup 2+^ overload and cell death显示文摘 | Aurora Arin B Mahmoud Ahmed I Luo Xiang Johnson Brett A van Rooij Eva Matsuzaki Satoshi Humphries Kenneth M Hill Joseph A Bassel-Duby Rhonda Sadek Hesham A Olson Eric N | 2012 | EN2012，，4： | 2 |
| 7 | Cascaded artificial neural networks for short-term load forecasting显示文摘 | Alfuhaid A S El SayedM A Mahmoud M S | 1997 | IEEE Trans on Power Systems1997，12，4： | 2 |
| 8 | A new catalytically active colloidal platinum nanocatalyst: the multi- armed nanostar single crystal显示文摘 | MAHMOUD M A TABOR C E EL-SAYED M A | 2008 | Journal of the American Chemi- cal Society2008，130，14： | 1 |
| 9 | Production of high protein quality noodles using wheat flour fortified with different protein products from lupine显示文摘 | MAHMOUD E A M NASSEF S L AMANY BASUNY M M | 2012 | Annals of Agricultural Science2012，57，2： | 1 |
| 10 | Fiber-Optic chemical sensor using polyaniline as modified cladding material显示文摘 | Yuan J M Mahmoud A | 2003 | Ieee Sensors Journal2003，3，1： | 1 |
| 11 | Detection of red ripe tomatoes on stem using image processing techniques 显示文摘 | HOSNA M M REZA A MAHMOUD O | 2011 | Journal of American Scionce2011，7，7： | 1 |
| 12 | Similarity analysis for effects of variable diffusivity and heat generation/absorption on heat and mass transfer for a MHD stagnation-point flow of a convective viscoelastic fluid over a stretching sheet with a slip velocity 显示文摘 | EL-HAWARY H M MOSTAFA A A MAHMOUD ABDEL- RAHMAN REDA G ABEER S E | 2013 | Mathematical Problems in Engineering2013，，： | 1 |
| 13 | Genotyping of kappa-casein gene in Egyptian buffalo bulls显示文摘 | Abdel Dayem A Mahmoud K Nawito M F | 2009 | Livestock Science2009，122，23： | 1 |
| 14 | X-ray diffraction of starches isolated from yellow corn sorghum,sordan and pearlmillet显示文摘 | Allah M A Foda Y H Mahmoud R M | 1987 | Starch1987，39，2： | 1 |
| 15 | Response of the Posterior Corneal Surface to Laser in Situ Keratomileusis for Myopia显示文摘 | Twa M D Roberts C Mahmoud A M | 2005 | Journal of Cataract & Refractive Surgery2005，31，1： | 1 |
| 16 | Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis 显示文摘 | MAHMOUD N N CAROTHERS A M GRUNBERG- ER D | 2000 | Carcinogenesis2000，21，： | 1 |
| 17 | Passivity and passification of time-delay systems显示文摘 | Mahmoud M S Ismail A | 2004 | J Math Anal Appl2004，292，1： | 1 |
| 18 | Design of fuzzy logic control system incorporating human expert knowledge for combine harvester显示文摘 | Mahmoud O Majid L Hossein M Reza A | 2010 | Expert Systems with Applications2010，，37： | 1 |
| 19 | Determination of Metformin in Pharmaceutical Preparations Using Potentiometry,Spectrofluorimetry and UV-visible Spectrophotometry显示文摘 | Saad S M Hassan Wagiha H Mahmoud Mohamed A F Elmosallamy | 1999 | Anal Chim Acta1999，378，13： | 1 |
| 20 | Cascaded artificial neural networks for short-term load forecasting 显示文摘 | ALFUHAID A S ELSAYED M A MAHMOUD M S | 1997 | IEEE Trans on Power Systems1997，12，4： | 1 |
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