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| 1 | 南极中山站极光形态的统计特征显示文摘利用极光全天空摄象机1995年和1997年在南极中山站观测的极光数据,对中山站上空极光的出现情况进行了统计分析。在南极中山站,午后(磁地方时1400~1800MLT)和子夜前后(2200~0300MLT)出现极光的情况比较多,在傍晚(1800~2200MLT)出现极光的情况要少一些;较强的极光主要也出现在午后和子夜附近。冕状极光主要出现在子夜附近和午后的极向侧和天顶,在傍晚出现很少;带状极光主要出现在午后和赤道侧的傍晚与子夜;极光浪涌主要出现在子夜前后;向日极光弧则主要出现在子夜前后,子夜前比子夜后多,极向和天顶比赤道侧多。除向日极光弧外,其它形态的极光在中山站的出现情况与Kp指数相关。中山站进入极光带的时间通常在午后。 | 胡红桥 刘瑞源 王敬芳 杨惠根 KAZUO MAKITA 王幸 NATSUO SATO | 1999 | 极地研究1999，11，1： | 22 |
| 2 | Hepatocellular carcinoma in extremely elderly patients:An analysis of clinical characteristics,prognosis and patient survival显示文摘瞄准:80 年或更多与肝细胞癌(HCC ) 识别病人的临床、预示的特征。方法:有 HCC 的 1310 个病人的一个总数在这研究被包括。80 年或更多的 91 个病人在 HCC 的诊断的时候被定义为极其老的组。>
或 = 的 234 个病人 50 年但是不到 60 年被认为是非老的组。结果:两性比率(到女性的男性) 比在非老的组在极其老的组(0.90:1 ) 是显著地更低的(3.9:1, P <
0.001 ) 。为 HBsAg 的积极的率在极其老的组和为显然在极其老的组增加的 HBsAg 和 HCVAb 否定的病人的比例是显著地更低的(P <
0.001 ) 。在下列参数没有有效差量:肿瘤,分级的孩子呸,肿瘤阶段,门静脉血栓形成或腹水的存在,和为 HCVAb 的积极的率的直径和数字。极其老的病人经常没收到外科疗法(P <
0.001 ) 并且他们是更可能的收到保守疗法(P <
0.01 ) 。基于与在二个组之间的全面病人比较的 Kaplan-Meier 方法在幸存曲线没有有效差量。然而,幸存曲线在有阶段 I/II 的极其老的病人是显著地更坏的,上演 I/II,孩子呸分级与非老的组比较的肝硬化。死亡的原因没在病人之中不同,并且大多数盒子甚至在极其老的病人死于肝相关的疾病。结论:在有好肝功能和好表演地位的病人,为 HCC 的好攻击的治疗可能改进幸存率,甚至在极其老的病人。 | Gengo Tsukioka Satoru Kakizaki Naondo Sohara Ken Sato Hitoshi Takagi Hirotaka Arai Takehiko Abe Mitsuo Toyoda Kenji Katakai Akira Kojima Yuichi Yamazaki Toshiyuki Otsuka Yutaka Matsuzaki Fujio Makita Daisuke Kanda Katsuhiko Horiuchi Tetsuya Hamada Mieko Kaneko Hideyuki Suzuki Masatomo Mori | 2006 | World Journal of Gastroenterology2006，12，1： | 7 |
| 3 | Cdx2 expression and its promoter methylation during metaplasia-dysplasia-carcinoma sequence in Barrett's esophagus显示文摘AIM:To examine how the expression of caudal type homebox transcription factor 2(Cdx2) is regulated in the development of malignancy in Barrett's esophagus.METHODS:Cdx2,mucin(MUC) series(MUC2,MUC5AC and MUC6),p53 and E-cadherin expression in Barrett's esophagus and adenocarcinoma specimens were examined by immunostaining.Isolated clusters of cells from(1) MUC2 and Cdx2-positive intestinal metaplastic mucosa;(2) MUC5AC and MUC6-positive,and MUC2 and Cdx2-negative high-grade dysplasia(HD),or intramucosal adenocarcinoma(IMC);and(3) MUC5AC,MUC6 and Cdx2-positive poorly-differentiated invasive adenocarcinoma(PDA) were analyzed by methylationspecific polymerase chain reaction using sets of primers for detecting methylation status of the Cdx2 gene.RESULTS:Most of the non-neoplastic Barrett's esophageal mucosa showing intestinal-type metaplasia with or without low-grade dysplasia was positive for E-cadherin,MUC series and Cdx2,but negative for p53.A portion of the low-grade to HD was positive for E-cadherin,MUC5AC,MUC6 and p53,but negative for MUC2 and Cdx2.The definite IMC area was strongly positive for MUC5AC,MUC6 and p53,but negative for MUC2 and Cdx2.Methylation of the Cdx2 promoter was not observed in intestinal metaplasia,while hypermethylation of part of its promoter was observed in hot dipped and IMC.Hypermethylation of a large fraction of the Cdx2 promoter was observed in PDA.CONCLUSION:Cdx2 expression is restored irrespective of the methylation status of its promoter.Apparent positive immunohistochemical results can be a molecular mark for gene silencing memory. | Kenji Makita Riko Kitazawa Shuho Semba Koto Fujiishi Miku Nakagawa Ryuma Haraguchi Sohei Kitazawa | 2013 | World Journal of Gastroenterology2013，19，4： | 5 |
| 4 | Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia显示文摘BACKGROUND Biliary atresia(BA)is a rare pediatric disease.AIM To compare the outcomes of laparoscopic portoenterostomy(Lap-PE)with those of laparotomy(Open-PE)at a single institution.METHODS The surgical outcomes of PE were retrospectively analyzed for patients with a non-correctable type of BA from 2003 to 2020.RESULTS Throughout the assessment period,119 patients received PE for BA treatment,including 66 Open-PE and 53 Lap-PE cases.Although the operation duration was longer(medians:for Open-PE,242 min;for Lap-PE,341 min;P<0.001),blood loss was considerably less(medians:for Open-PE,52 mL;for Lap-PE,24 mL;P<0.001)in the Lap-PE group than in the Open-PE group.The postoperative recovery of the Lap-PE group was more favorable;specifically,both times to resume oral intake and drain removal were significantly shorter in the Lap-PE group.Complete resolution of jaundice was observed in 45 Open-PE cases and 42 Lap-PE cases,with no statistically significant difference(P=0.176).Native liver survival rates were>80%for both groups for the first half year post surgery,followed by a gradual decrease with time;there were no statistically significant differences in the native liver survival rates for any durations assessed.CONCLUSION Lap-PE could be a standard therapy for BA. | Chiyoe Shirota Akinari Hinoki Takahisa Tainaka Wataru Sumida Fumie Kinoshita Kazuki Yokota Satoshi Makita Hizuru Amano Yoichi Nakagawa Hiroo Uchida | 2022 | World Journal of Gastrointestinal Surgery2022，14，1： | 2 |
| 5 | Reactive glycosylation endproducts in diabetic uraemia and treatment of renal failure显示文摘 | Makita Z Bucala R Rayfield EJ | 1994 | Lancet1994，343，： | 1 |
| 6 | Chemopreventive effect of a xanthine oxidase inhibitor,1'-acetoxychavicol acetate,on rat oral carcinogenesis显示文摘 | Ohnishi M Tanaka T Makita H | 1996 | Jpn J Cancer Res1996，87，4： | 1 |
| 7 | Immonohistochemical localization of microcystin-LR in the liver of mice: a study on the pathogenesis of microcystin-LR induced hepatotoxicity 显示文摘 | Yoshida T Makita Y Tsutsumi T | 1996 | Toxicol Pathol1996，，26： | 1 |
| 8 | Synthesis of single wall carbon nanotubes by using arc discharge technique in nitrogen atmosphere 显示文摘 | Makita Y Suzuki S Kataura H | 2005 | The European Physical Journal D - Atomic Molecular Optical and Plasma Physics2005，34，1： | 1 |
| 9 | Magneticproperties of sintered Sendust alloys using powders granulatedby spray drying method显示文摘 | KISHIMOTO Y YAMASHITA 0 MAKITA K | 2003 | Journal of Materials Science2003，38，16： | 1 |
| 10 | Identification of epistaticinteraction involved in obesity using the KK/Ta mouse as a type2 diabetes model: is Zn-?2-glycoproteinb-l a candidate gene forobesity?显示文摘 | GOHDA T MAKITA Y SHIKE T | 2003 | Diabetes2003，52，8： | 1 |
| 11 | Advanced glycosylation end products in continuous ambulatory peritoneal dialysis patients显示文摘 | Korbet SM Makita Z Firanek CA | 1993 | Am J Kidney Dis1993，22，： | 1 |
| 12 | Annual change in pulmonary function and clinical phenotype in chronic obstructive pulmonary disease显示文摘 | Nishimura M Makita H Nagai K | 2012 | Am J Respir Crit Care Med2012，185，1： | 1 |
| 13 | Annual change in pulmonary function and clinical phenotype in chronic obstructive pulmonary disease 显示文摘 | Nishimura M Makita H Nagai K | 2012 | Am J Respir Crit Care Med2012，185，1： | 1 |
| 14 | Comprehensive in vivo micro-vascular imaging of the human eye by dual- beam-scan Doppler optical coherence angiography显示文摘 | Makita S Jaillon F Yamanari M | 2011 | Optics Express2011，19，2： | 1 |
| 15 | MR imaging of Tornwaldt's cysts显示文摘 | Ikushima I Korogi Y Makita O | 1999 | AJR1999，172，： | 1 |
| 16 | Involvement of beta 2-glycoprotein I and anticardiolipin antibodies in oxidatively modified low-density lipoprotein uptake by macrophages 显示文摘 | Hasunuma Y Matsuura E Makita Z | 1997 | Clin Exp Immunol1997，107，3： | 1 |
| 17 | Alendronate is more effective than elcatonin in improving pain and quality of life in postmenopausal women with osteoporosis显示文摘 | Iwamoto J Makita K Sato Y | 2011 | Osteoporos Int2011，22，： | 1 |
| 18 | Ctdifferentiation between necrotic and nonecrotic small bowel in closed loop and strangulating obstruction显示文摘 | IKUSHIMA I MATSUMITO N | 1999 | Abdom Lmaging1999，24，2： | 1 |
| 19 | Prolonged postischemic regional left ventricular delayed relaxation or diastolic asynchrony detected by color kinesis fol- lowing coronary vasospasm 显示文摘 | Ishii K Miwa K Makita T | 2003 | Am J Cardiol2003，91，： | 1 |
| 20 | Determination of totalplasma homocysteine and related aminothiols by gaschromatography with flame photometric detection显示文摘 | Kataoka H Takagi K Makita M | 1995 | JChromatogr B Biomed Appl1995，664，2： | 1 |
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