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| 1 | Viral IL-6-Induced cell proliferation and immune evasion of interferon activity显示文摘 | Malini C Julie O Giovanna B | 2002 | Science2002，298，11： | 1 |
| 2 | Raman spectroscopy studies for diagnosis of cancers in human uterine cervix 显示文摘 | Krishna C M Prathima N B Malini R | 2006 | Vibrational Spectroscopy(S0924-2031)2006，41，1： | 1 |
| 3 | ImprovedWigner-Ville distribution performance by signaldecomposition and modified group delay 显示文摘 | Narasimhan S V Nayak Malini B | 2003 | SignalProcessing2003，83，12： | 1 |
| 4 | Inhibition of steroid sulphatase activity by tricyclic coumarin sulphamates 显示文摘 | MALINI B PUROHIT A GANESHAPILLAI D | 2000 | J Steroid Biochem Mol Biol2000，75，45： | 1 |
| 5 | Raman spectroscopy studies for diagnosis of cancers in human uterine cervix显示文摘 | C Murali Krishna N B Prathima R Malini | 2006 | Vibrational Spectroscopy2006，41，1： | 1 |
| 6 | Fc receptors and their interaetions with immunoglobulins显示文摘 | Malini R Pamela J B | 1996 | Annu Rev Cell Dev Biol1996，12，： | 1 |
| 7 | Improved Wigner-Ville distribution performance by signal decomposition and modified group delay显示文摘 | Narasimhan S V Nayak Malini B | 2003 | Signal Processing2003，83，12： | 1 |
| 8 | Vermicomposting ofwater hyacinth with poultry litter using rotary drum reactor 显示文摘 | Patil J H Sanil P H Malini B M | 2012 | Journal of Chemical and Pharmaceutical Research2012，4，5： | 1 |
| 9 | Raman spectroscopy studies for diagnosis of cancers in human uterine cervix显示文摘 | C M Krishna N B Prathima R Malini | 2006 | ~ib Spectrose2006，41，1： | 1 |
| 10 | Cardiac glycosides Drug interactions of clinical significance显示文摘 | Malini PL | 1995 | Drug Saf1995，12，2： | 1 |
| 11 | Nonfermenting Gram-NegativeBacilli Infections in a Tertiary Care Hospital in Kolar, Karnataka显示文摘 | Malini A Deepa E Gokul B | 2009 | J Lab Physicians2009，1，2： | 1 |
| 12 | Potent active site- directed inhibition of steroid sulphatase by trieyclie coumarin- based sulphamates显示文摘 | WOO LW PUROHIT A MALINI B | 2000 | ChemBiol2000，7，10： | 1 |
| 13 | Synthesis of some new 2,4-disubstituted thiazoles as possible anti- bacterial and anti-inflammatory agents 显示文摘 | Hona B S Malini K V Rao B S | 2003 | Eur J MedChem2003，38，： | 1 |
| 14 | Graft loss among renal-transplant recipients with early reduction of immunosuppression for BK viremia显示文摘AIM To review the incidence of graft loss and acute rejection among renal transplant recipients with early reduction of immunosuppression for BK viremia.METHODS We performed a retrospective analysis of consecutive de-novo kidney-only transplants from January 2009 to December 2012 to evaluate the incidence of Polyomavirus associated nephropathy(PyV AN). Recipient plasma was screened for BKV DNA via quantitative polymerase chain reaction(PCR) at months 1,3,6,9 and 12 post-transplant and on worsening graft function.Immunosuppression was reduced at ≥ 3-log copies/mL. Those with viremia of ≥ 4-log copies/mL(presumptive PyV AN) underwent renal transplant biopsy. Presumptive Py VAN(PP) and definitive Py VAN(DP; biopsy-proven) were treated by immunosuppression reduction(IR) only. RESULTS Among 319 kidney transplant recipients,the median age was 53 years(range 19-83),65.8% were male,and 58.9% were white. Biopsy-proven acute rejection was found in 18.5% within 0-168 wk. Death-censored graft loss occurred in 5.3%(n = 17) and graft loss attributable to PyV AN was 0.6%(n = 2). Forty-seven patients were diagnosed with PP(14.7%) and 18(5.6%) with DP. Graft loss among participants with PyV AN(8.5%) and those without(4.8%) was not significantly different. Deceased donor kidney transplantation(OR = 2.3,95%CI = 1.1-4.6) and AR(OR = 2.3,95%CI = 1.2-4.7) were associated with Py VAN in the multivariate analysis. BK viremia between 3 and 4-log copies/mL occurred in 27 patients,all of whom underwent IR. Of these,16(59%) never developed PyV AN while 11(41%) developed PyV AN(4 DP,7 PP) within a range of 11-39 wk. CONCLUSION Instituting an early reduction of immunosuppression,in the absence of adjunctive antivirals,is effective at preventing PyV AN and may be associated with a lower incidence of graft-loss without a reciprocal increase in the incidence of acute rejection. | Marwan M Azar Roland Assi Aziz K Valika David B Banach Isaac E Hall Marie-Louise Landry Maricar F Malinis | 2017 | World Journal of Transplantation2017，7，5： | 0 |
| 15 | Role of ions and ion channels in capacitation and acrosome reaction of spermatozoa显示文摘Capacitation and acrosome reaction are important prerequisites of the fertilization process. Capacitation is a highlycomplex phenomenon occurring in the female genital tract, rendering the spermatozoa capable of binding and fusionwith the oocyte. During capacitation various biochemical and biophysical changes occur in the spermatozoa and thespermatozoal membranes. Ions and ion channels also play important roles in governing the process of capacitation bychanging the fluxes of different ions which in turn controls various characteristics of capacitated spermatozoa. Alongwith the mobilization of ions the generation of free radicals and efflux of cholesterol also plays an impo~.nt role in thecapacitation state of the spermatozoa. The generation of free radical and efflux of cholesterol change the mechano-dynamic properties of the membrane by oxidation of the polyunsaturated lipids and by generating the cholesterol freepatches. The process of capacitation renders the spermatozoa responsive to the inducers of the acrosome reaction. Theglycoprotein zona pellucida 3 (ZP3) of the egg coat zona pellucida is the potent physiological stimulator of the acro-some reaction; progesterone, a major component of the follicular fluid, is also an inducer of the acrosome reaction.The inducers of the acrosome reaction cause the activation of the various ion-channels leading to high influxes of calci-um, sodium and bicarbonate. The efflux of cholesterol during the process of capacitation alters the permeability of themembrane to the ions and generate areas which are prone to fusion and ve.siculation process during the acrosome reactioa. this review focuses mainly on effects of the ion and ion-channels, free radicals, and membrane fluidity changesduring the process of capacitation and acrosome reaction. | Sharad B Purohit Malini Laloraya G.Pradeep Kumar | 1999 | Asian Journal of Andrology1999，1，3： | 0 |
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