| 4 | MicroRNA-155 expression suggests a sex disparity in innate lymphoid cells at the single-cell level显示文摘MicroRNAs(miRNAs)are small noncoding RNAs that control gene expression at the post-transcriptional level,thereby serving as important cellular regulators.1 However,miRNA expression in specific human cellular subtypes,especially at the single-cell level,remains largely unexplored.In this study,a novel method called the PrimeFlow^(TM) RNA Assay2 was used to directly monitor miRNA expression in the cell.Notably,we demonstrate for the first time that human innate lymphoid cells(ILCs)express miR-155.We further demonstrate a clear distinction between the sexes,with a significant increase in the number of ILCs expressing miR-155 in female-derived cells compared with male-derived cells upon in vitro stimulation. | Carina Malmhäll Julie Weidner Madeleine Rådinger | 2020 | Cellular & Molecular Immunology2020，17，5： | 0 |
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