|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models显示文摘表示为基于 radiopharmaceutical 的成像为生物体之发光成像或 HSV1 thymidine kinase (HSV1-TK ) 编码任何一个萤火虫酶(fLuc ) 的记者 transgene 的 lentiviral 向量的二种新类型被构造监视人的胚胎的干细胞(hESC ) 在在移植以后的活老鼠的嫁接和增长。任何一个 transgene 的组成的表示没在文化改变 hESCs 的性质。我们下次在 SCID 鼠标监视了 teratomas 的形成到测试(1 ) 是否修改基因的 hESCs 维持他们的发展 pluripotency,并且(2 ) 是否支撑了记者基因表示,允许 noninvasive,在一个活鼠标模型的 hESC 衍生物的整个身体的成像。我们在接种以后从修改基因的房间以及野类型的 hESCs 2-4 月的两种类型观察了 teratoma 形成。用一个光成像系统,从 fLuc-transduced hESCs 的生物体之发光容易在在摸得出的肿瘤能被检测以前,长忍受 teratomas 的老鼠被检测。开发一个 noninvasive 成像方法对诊所更容易地可译,我们也利用了 HSV1-TK 和它的特定的底层, 1-(2 鈥 ? deoxy-2 鈥 ?fluoro- 尾 - D-arabinofuranosyl )-5-[125I]iodouracil ([125I ] FIAU ) ,记者 / 探查对。在全身的管理以后,[125I ] FIAU 是仅仅由编码 transgene 的 HSV1-TK 酶的 phosphorylated 并且在 transduced 以内保留(并且移植) 房间,由单个光子的排放允许敏感、量的成像计算了断层摄影术。象这些那样的 Noninvasive 成像方法可以使我们能在实时接受者以内重复地监视移植人的干细胞的存在和分发在上一通过记者基因的表达式长期。 | Martin G Pomper Holly Hammond Xiaobing Yu Zhaohui Ye Catherine A Foss Doris D Lin James J Fox Linzhao Cheng | 2009 | Cell Research2009，19，3： | 9 |
| 2 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 3 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | 2012 (9859)2012，，9859： | 3 |
| 4 | Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial显示文摘 | Ronald P DeMatteo Karla V Ballman Cristina R Antonescu Robert G Maki Peter WT Pisters George D Demetri Martin E Blackstein Charles D Blanke Margaret von Mehren Murray F Brennan Shreyaskumar Patel Martin D McCarter Jonathan A Polikoff Benjamin R Tan Kouros | 2009 | The Lancet2009，，9669： | 2 |
| 5 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | The Lancet2012，，9859： | 2 |
| 6 | An effective stress model for liquefaction显示文摘 | Finn W D L Lee K W Martin G R | 1977 | Journal of the Geotechnical Engineering Division ASCE1977，103，6： | 2 |
| 7 | Distribution of beta-glucanases within the genus Bacillus 显示文摘 | Martin D F Priest F G Todd C | 1980 | Appl Environ Microbiol1980，40，6： | 1 |
| 8 | 显示文摘 | MARTIN P D JONES G R STRINGER F WILSON I D | 2003 | Analyst2003，128，： | 1 |
| 9 | Hyper-X StageSeparation-Simulation Development and Results显示文摘 | Reubush D E Martin J G Robinson J S | 2001 | AIAA/NAL-NASDA-ISAS International Space Planes and Hypersonic Systems and Technologies Conference2001，10，： | 1 |
| 10 | Rheologic reflection in hypertriglyceridemia-induced pancreatitis 显示文摘 | Martin D McCann E G|ynn P | 2009 | South Med J2009，102，10： | 1 |
| 11 | Seismic Response and Liq- uefaction of Sands显示文摘 | Finn W D Byrne P M Martin G R | 1976 | Journal 05 Geotechnical Engineering Di vision ASCE1976，102，8： | 1 |
| 12 | Traumatic injuries of peripheral nerves: a review with emphasis on surgical indication 显示文摘 | Martins R S Bastos D Siqueira M G | 2013 | Arq Neuropsiquiatr2013，71，10： | 1 |
| 13 | Using simula- tion to inteIpret a discrete time survival model in a complex biological system: fertility and lameness in dairy cows显示文摘 | Christopher D H Jonathan N H Martin J G | 2014 | Plos 0ne2014，9，8： | 1 |
| 14 | Histologic Pathologies of the Myocardium in Septic Shock: A Prospective Observational Study显示文摘 | Christian A. Schmittinger Martin W. Dünser Christian Torgersen Günter Luckner Ingo Lorenz Stefan Schmid Michael Joannidis Patrizia Moser Walter R. Hasibeder Milo Halabi Christina M. Steger | 2013 | Shock2013，，4： | 1 |
| 15 | Modeling of brazing processes that use coating and interlayers显示文摘 | Liu S Olsen D L Martin G P | 1991 | Welding Journal1991，70，8： | 1 |
| 16 | Influence of a Commercial Yeast Supplement on the in Vitro Ruminal Fermentation显示文摘 | Martin S A Nisbet D J Dean R G | 1989 | Nutr Rep Int1989，40，： | 1 |
| 17 | Endo-, para-, and eco-dormancy: physiological terminology and classification for dormancy research 显示文摘 | Lang G A Early J D Martin G C | 1987 | Horticultural Science1987，22，： | 1 |
| 18 | Fundamentals of liquefaction under cyclic loading显示文摘 | MARTIN G R FINN W D L SEED H B | 1975 | Journal of the Geotechnical Engineering Division ASCE1975，101，5： | 1 |
| 19 | The key roles of elongases and desaturases in mammalian fatty acid metabolism:insights from transgenic mice显示文摘 | GUILLOU H ZADRAVEC D MARTIN P G | | 0，，： | 1 |
| 20 | Bosentan attenuates right ventricu- lar hypertrophy and fibrosis in normobaric hypoxia model of pulmonary hyperten- sion显示文摘 | Choudhary G Troncales F Martin D | 2011 | J Heart Lung Transplant2011，30，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员