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| 1 | Comparison of long-term outcome between patients aged 〈 65 years vs. ≥ 65 years after atrial fibrillation ablation显示文摘Background Atrial fibrillation (AF) is the most frequent arrhythmia, and its prevalence is increasing with aging. We aimed to com-pare the long-term outcome data of patients 〈 65 years vs.≥ 65 years who underwent catheter ablation (CA) for drug-refractory AF. MethodsConsecutive patients with primary pulmonary vein isolation performed between March 2001 and December 2011, and those who completeda five-year of follow-up were divided into two groups: patients aged 〈 65 years into group 1, and patients aged ≥ 65 into group 2. Long-termoutcome data concerning mortality, thromboembolic events (TE) and success rates were compared between these groups. Results A totalnumber of 390 patients were included, group 1 contained 310 patients, and 80 patients in group 2. In group 2, patients had more often impairedrenal function (P 〈 0.001) and thyroid disease (P = 0.047). A total of fifteen patients died during the 6.63 ± 2.1 years of follow-up, with a sig-nificantly higher incidence in the older group (8/80 vs. 7/310 patients, P = 0.004). The majority of fatal outcome was due to cancerous dis-eases in both groups. No difference was observed concerning the long-term TE rate (12/310 vs. 4/80 patients, P = 0.75). Rhythm controlfailed in 25.9% of the patients, with no difference between the groups: 26.4% in group 1 vs. 23.7% in group 2 (P = 0,67), ConclusionsDespite growing prevalence of AF in aging population, the elderly patients are underrepresented in CA procedures. Similar clinical successand TE complication rate are observed between the age-groups. Our data suggest more liberal criteria might be applied while selecting pa-tients for AF ablation. | Zsuzsanna Kis Anna ME Noten Mihran Martirosyan Astrid A Hendriks Rohit Bhagwandien Tamas Szili-Torok | 2017 | Journal of Geriatric Cardiology2017，14，9： | 3 |
| 2 | Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin:potential therapeutic relevance显示文摘 | Martirosyan A Clendening JW Goard CA | 2010 | BMC Cancer2010，10，： | 1 |
| 3 | Brucella ~8 1,2 cyclic glucan is an activator of human and mouse dendritic cells显示文摘 | Martirosyan A Perez-Gutierrez C Banchereau R | 2012 | PLoS Pathog2012，8，10： | 1 |
| 4 | Lovas- tatin induces apoptosis of ovarian cancer cells and synergi- zes with doxorubicin: potential therapeutic relevance显示文摘 | Martirosyan A Clendening JW Goard CA | 2010 | BMC Cancer2010，10，： | 1 |
| 5 | Neu- trophils exert a suppressive effect on Thl responses to intracellular pathogen Brucella abortus 显示文摘 | Barquero-Calvo E Martirosyan A Ordonez-Rueda D | 2013 | PLoS Pathog2013，9，2： | 1 |
| 6 | Struc-tural and tectonic peculiarities of structure and prospects ofoil and gas potential of the northern part of Barents-Kara re-gion显示文摘 | Dolgunov K A Martirosyan V N Vasilieva E A | 2011 | Oil and Gas Geology2011，，6： | 1 |
| 7 | Two subunits of the Drosophila mediator comples act together to control cell affinity显示文摘 | Janody F Martirosyan Z Benlali A | 2003 | Development2003，130，16： | 1 |
| 8 | Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevance 显示文摘 | MARTIROSYAN A CLENDENING J W GOARD C A | 2010 | BMC Cancer2010，10，： | 1 |
| 9 | Tribological properties of bentonite thickener-containing greases显示文摘 | Pogosyan A K Martirosyan T R | | 0，，03： | 1 |
| 10 | An evolutionary strategy for a stealthy intracellular Brucella pathogen显示文摘 | Martirosyan A Moreno E Gorvel JP | 2011 | Immunol Rev2011，240，： | 1 |
| 11 | Lipopolysaccharides with acylation defects potentiate TLR4 signaling and shape T cell re- sponses 显示文摘 | Martirosyan A Ohne Y Degos C | 2013 | PLoSOne2013，8，55： | 1 |
| 12 | Estimation of earthquake source parameters and site response in Anchorage, Alaska from strong motion network data using generalized inversion method 显示文摘 | DUTYA U BISWAS N MARTIROSYAN A | 2003 | Physies of the Earth and Planetary Interiors2003，137，： | 1 |
| 13 | Strong-motion records of the 2002 Denali Fault,Alaska earthquake显示文摘 | Martirosyan A Ansen RH Ratehkovski N | 2004 | Earthquake Spectra2004，20，： | 1 |
| 14 | Impact of surfactant struc- ture on the tribological properties of bentonite-based greases 显示文摘 | Pogosian A K Martirosyan T R | 2007 | Journal of Tribology2007，129，4： | 1 |
| 15 | An evolutionary strate gy for a stealthy interacellular Brucella pathogen显示文摘 | Martirosyan A Moreno E Gorvel JP | 2011 | Immunol Rev2011，240，1： | 1 |
| 16 | An evolutionary strategy for a stealthy intracellular Brucella pathogen显示文摘 | Martirosyan A Moreno E Gorvel JP | | 0，，01： | 1 |
| 17 | An evolutionary strategy for a stealthy intracellular Brucella pathogen显示文摘 | Martirosyan A Moreno E Gorvel JP | 2011 | Immunological reviews2011，240，1： | 1 |
| 18 | Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin:Potential therapeutic relevance显示文摘 | MARTIROSYAN A CLENDENING J W GOARD C A | 2010 | BMC Cancer2010，10，： | 1 |
| 19 | An Inter-Cluster Communication Based Energy Aware and Fault Tolerant Protocol for Wireless Sensor Networks显示文摘 | Boukerche A Martirosyan A Pazzi R | 2008 | Mobile Networks and Applications2008，13，6： | 1 |
| 20 | An evolutionary strategy for a stealthy intracellular Brucella pathogen显示文摘 | Martirosyan A Moreno E Gorvel J P | 2011 | Immunological reviews2011，240，1： | 1 |
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