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166篇 您的检索式:作者名="MAYNE M"
    题名 作者 年代 出处 被引量
1miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus显示文摘AIM: To investigate miR-200 family expression in Barrett's epithelium, gastric and duodenal epithelia, and esophageal adenocarcinoma. METHODS: Real-time reverse transcriptase-polymerase chain reaction was used to measure miR-200, ZEB1 and ZEB2 expression. Ingenuity Pathway Analysis of miR-200 targets was used to predict biological outcomes. RESULTS: Barrett's epithelium expressed lower levels of miR-141 and miR-200c than did gastric and duodenal epithelia (P < 0.001). In silico analysis indicated roles for the miR-200 family in molecular pathways that distinguish Barrett's epithelium from gastric and duodenalepithelia, and which control apoptosis and proliferation. All miR-200 members were downregulated in adenocarcinoma (P < 0.02), and miR-200c expression was also downregulated in non-invasive epithelium adjacent to adenocarcinoma (P < 0.02). The expression of all miR-200 members was lower in Barrett's epithelium derived high-grade dysplastic cell lines than in a cell line derived from benign Barrett's epithelium. We observed signif icant inverse correlations between miR-200 family expression and ZEB1 and ZEB2 expression in Barrett's epithelium and esophageal adenocarcinoma (P < 0.05). CONCLUSION: miR-200 expression might contribute to the anti-apoptotic and proliferative phenotype of Barrett's epithelium and regulate key neoplastic processes in this epithelium.Cameron M Smith David I Watson Mary P Leong George C Mayne Michael Z Michael Bas PL Wijnhoven Damian J Hussey 2011World Journal of Gastroenterology2011,17,8:13
2Antisense oligodeoxynucleotide inhibition of tumor necrosis factor-alpha expression is neuroprotective after intracerebral hemorrhage显示文摘Mayne M Ni W Yan HJ 2001Stroke2001,32,1:1
3PCSK9-deficient mice exhibit impaired glucose tolerance and pancreatic islet abnormalities显示文摘Mbikay M Sirois F Mayne J 2010FEBS Lett2010,584,4:1
4Antisense oligodeoxynucleotide inhibi- tion of tumor necrosis factor-a expression is neuroprotec tive after in- tvacevebral hemorrhage 显示文摘Mayne M Ni W Yan H J 2010Stroke2010,32,3:1
5AdenosineA2A receptor activation reduces proinflammatory events and decrease cell death following intracerehral hemorrhage 显示文摘Mayne M Fotheringham J Yan HJ 2001Ann Neurol2001,49,:1
6Effect of level of oil inclusion in the diet of dairy cows at pasture on animal performance and milk composition properties显示文摘Fearon A M Mayne C S Beattie J A M 2004J Sci Food Agri2004,84,:1
7The different inclusing of naked oats in the concentrate offered to dairy cows on milk production,milk fat composition and properties显示文摘Fearon A M Mayne C S Marsden S 1996J Sci Food gri1996,72,:1
8PCSK9-deficient mice exhibit impaired glucose tolerance and pancreatic islet abnormalities显示文摘Mbikay M Sirois F Mayne J 0,,:1
9Antisense Oligodeoxynucleotide inhibition of tumor necrosis factor - αexpression is neuroprotective after intracerebral hemorrhage显示文摘Mayne M Ni W Yan HJ 2001Stroke2001,32,:1
10Antisense oligodeoxynucleotide inhibition of tumor necrosis factor-alpha expression is neuroprotective after intracerebral hemorrhage显示文摘 Ni W Yan HJ 2001Stroke2001,32,:1
11FOXP3 expression is upregulated in CD4 T cells in progressive HIV-1 infection and is a marker of disease severity显示文摘Suchard M S Mayne E Green V A 0,,07:1
12Antisense oligodeoxynucleo tide in hibition of TNF - α expression is neuroprotective after intracerebral hemorrhage显示文摘Mayne M Ni W Yan HJ 2001Stroke2001,32,1:1
13Min-max feedback model predictive control for constrained linear systems 显示文摘SCOKAERT P O M MAYNE D Q 1998IEEE Transactions on Automatic Control1998,43,8:1
14Antisense oligodeoxynucleotide inhibition of tumor necrosis factor-ctexpression is neuroprotective after intracerebral hemorrhage显示文摘Mayne M Ni W Yan HJ 2001Stroke2001,32,3:1
15Antisense oligodeoxynucleotide inhibition of tumor necrosis factor-alpha expression is neuroprotective after intracerebral hemorrhage显示文摘Mayne M Ni W Yan HJ 2001Stroke2001,32,:1
16Antisense oligodeoxynucleotide inhibition of tumor necrosis factor-α expression is neuroprotective after intracerebral hemorrhage显示文摘MAYNE M NI W YAN HJ 2001Stroke2001,32,3:1
17Constrained Model Predictive Control: Stability and Optimality显示文摘Mayne D Q RawlingsJ B Rao C V Scokaert P 0 M 2000Automatica2000,36,6:1
18Robust model predictive control of constrained linear systems with bounded disturbances显示文摘Mayne D Q Seron M M Rakovic S V 2005Automatica2005,41,2:1
19Constrained model predictive control:Stability and optimality显示文摘Mayne D Q Rawlings J B Rao C V Scokaert P O M 0,,06:1
20Constrained Model Predictive Control: Stability and Optimality 显示文摘D Q Mayne J B Rawlings C V Rao & P O M Scokaert 2000Automatica2000,36,:1
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