|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Hematopoietic stem cell-derived adipocytes and fibroblasts in the tumor microenvironment显示文摘The tumor microenvironment(TME) is complex and constantly evolving. This is due, in part, to the crosstalk between tumor cells and the multiple cell types that comprise the TME, which results in a heterogeneous population of tumor cells and TME cells. This review will focus on two stromal cell types, the cancerassociated adipocyte(CAA) and the cancer-associated fibroblast(CAF). In the clinic, the presence of CAAs and CAFs in the TME translates to poor prognosis in multiple tumor types. CAAs and CAFs have an activated phenotype and produce growth factors, inflammatory factors, cytokines, chemokines, extracellular matrix components, and proteases in an accelerated and aberrant fashion. Through this activated state, CAAs and CAFs remodel the TME, thereby driving all aspects of tumor progression, including tumor growth and survival, chemoresistance, tumor vascularization, tumor invasion, and tumor cell metastasis. Similarities in the tumorpromoting functions of CAAs and CAFs suggest that a multipronged therapeutic approach may be necessary to achieve maximal impact on disease. While CAAs and CAFs are thought to arise from tissues adjacent to the tumor, multiple alternative origins for CAAs and CAFs have recently been identified. Recent studies from our lab and others suggest that the hematopoietic stem cell, through the myeloid lineage, may serve as a progenitor for CAAs and CAFs. We hypothesize that the multiple origins of CAAs and CAFs may contribute to the heterogeneity seen in the TME. Thus, a better understanding of the origin of CAAs and CAFs, how this origin impacts their functions in the TME, and thetemporal participation of uniquely originating TME cells may lead to novel or improved anti-tumor therapeutics. | Ying Xiong Lindsay T Mc Donald Dayvia L Russell Ryan R Kelly Katie R Wilson Meenal Mehrotra Adam C Soloff Amanda C LaRue | 2015 | World Journal of Stem Cells2015，7，2： | 6 |
| 2 | Magnetic resonance studies of a gas-solids fluidised bed:Jet-jet and jet-wall interactions显示文摘Magnetic resonance imaging(MRI)gave images of air jets from orifices in the distributor plate of a bed of poppy seeds.Attention focused on two features:(1)The interaction between nearby vertical jets from two,three or four orifices;(2)Wall effects,where one or more orifices created vertical jets near the vertical wall of the cylinder containing the particle bed.The results show that nearby jets are mutually attracted.Likewise a jet near a wall bends out of the vertical,towards the wall.For multiple adjacent jets,the jet lengths show dependence on orifice layout:the lengths are in reasonable agreement with published measurements,by other methods,for single jets.The MRI gives three-dimensional images of the single jets and of multiple jets,separate or merging. | Meenal Pore Daniel J.Holland Thusara C.Chandrasekera Christoph R.Müller Andrew J.Sederman John S.Dennis Lynn F.Gladden John F.Davidson | 2010 | Particuology2010，8，6： | 2 |
| 3 | Symptoms and Subtypes in Pediatric Functional Dyspepsia: Relation to Mucosal Inflammation and Psychological Functioning显示文摘 | Jennifer V Schurman Meenal Singh Vivekanand Singh Nancy Neilan Craig A Friesen | 2010 | Journal of Pediatric Gastroenterology and Nutrition2010，，3： | 2 |
| 4 | Magnetic resonance studies of jets in a gas-solid fluidised bed显示文摘Magnetic resonance imaging (MRI) has been used to study the behaviour of jets at the distributor of a 50 mm diameter fluidised bed of 0.5 mm diameter poppy seeds. Two perforated-plate distributors were examined, containing either 10 or 14 holes, each 1 mm diameter. Ultra-fast MR imaging was able to show the transient nature of the upper parts of the jets, where discrete bubbles are formed. Imaging in 3D showed that the central jets were the longest for flow rates below minimum fluidisation. Above minimum fluidisation, the outer jets, nearest the wall of the fluidised bed, arched inward towards the central axis. In this latter case, interpretation of the time-averaged 3D image required the use of ultra-fast MR imaging to identify the approximate height above the distributor at which discrete bubbles were formed. The apparently continuous void extending along the central axis above this height in the time-averaged 3D image was thus identified, using ultra-fast MR imaging, as representing the averaged paths of released bubbles. Time-averaged MR velocity mapping was also used to identify dead zones of stationary particles resting on the distributor between the jets. The dead zones could be observed when the superficial velocity of the gas approached minimum fluidisation, but they were smaller than those observed at lower gas superficial velocity. Comparable images of a single jet through 1.2 mm diameter poppy seeds from MRI and electrical capacitance volume tomography (ECVT) are also demonstrated. | Meenal Pore Thusara C. Chandrasekera Daniel J. Holland Aining Wang Fei Wang Qussai Marashdeh Michael D. Mantle Andrew J. Sederman Liang-Shih Fan Lynn F. Gladden John S. Dennis | 2012 | Particuology2012，10，2： | 2 |
| 5 | Geochemical signatures of Mesoproterozoic siliciclastic rocks of the Kaimur Group of the Vindhyan Supergroup,Central India显示文摘The Upper Kaimur Group of the Vindhyan Supergroup in Central India,primarily consists of three rock types-DhandraulSandstone,Scarp Sandstone and Bijaigarh Shale.Mineralogically and geochemically,they are quartz arenite,sublitharenite to litharenite and litharenite to shale in composition,respectively.The A-CN-K ternary plot and CIA and ICV values suggest that the similar source rocks suffered severe chemical weathering,under a hot-humid climate in an acidic environment with higher PCO2,which facilitated high sediment influx in the absence of land plants.Various geochemical discriminants,elemental ratios like K2O/Na2O,Al2O3/TiO2,SiO2/MgO,La/Sc,Th/Sc,Th/Cr,GdN/YbN and pronounced negative Eu anomalies indicate the rocks to be of post-Archean Proterozoic granitic source,with a minor contribution of granodioritic input,in a passive margin setting.The sediments of the Upper Kaimur Group were probably deposited in the interglacial period in between the Paleoproterozoic and Neoproterozoic glacial epochs. | Meenal Mishra Shinjana Sen | 2010 | Chinese Journal Of Geochemistry2010，29，1： | 2 |
| 6 | Role of Cbfa1/Runx2 in the fluid shear stress induction of COX-2 in osteoblasts显示文摘 | Meenal M Masatomo S Carol P | 2006 | Biochem Biophys Res Commun2006，341，4： | 1 |
| 7 | Decomposition and Hydrocarbon Growth Processes for Hexadienes in Nonpremixed Flames 显示文摘 | MeEnally C S Lisa D P | 2008 | Combustion and Flame2008，152，： | 1 |
| 8 | Enzymatic hydrolysis of castor oil:Process intensification studies 显示文摘 | Meenal S Puthli Virendra K Rathod Anirnddha B Pandit | 2006 | Biochemical Engineering Journal2006，31，1： | 1 |
| 9 | Geochemistry of Late Archaean shaly BIF formed by oxic exogenic processes: an example from Ramagiri schist belt,Dharwar Craton, India显示文摘The central block of the auriferous Ramagiri schist belt, in the Eastern Dharwar Craton, India consists of bimodal volcanics(mafic-felsic), shaly BIF and metasedimentary rocks. Geochemical studies of the associated shaly BIF have indicated the enrichment of the major and trace elements such as Si O2, Al2O3, Ti O2, K2 O, Mg O, Fe2O3(T),Zr, Y, Cr, Ni, alkali and alkaline earth elements indicates that the clastic component of the shaly BIF had their contribution from the contemporaneous bimodal volcanics.The concave chondrite normalized REE patterns share ubiquitously anomalous positive cerium anomaly, absence of positive europium anomaly and the overall HREE enrichment. The REE patterns resemble those from the modern day sea water, except for positive Ce anomaly. The data suggests that arc related bimodal volcanism had been the plausible source of Fe, silica, REE and other trace elements. The coherent behaviour of Fe, Ti, Mn and P with the REEs indicates that they got incorporated from Fe–Ti–Mn bearing primary minerals and secondary products like clays. The variability of REE patterns in the BIF formation samples probably results from the differences in scavenging efficiency. The BIF bears signatures of mixing of the contemporaneous clastic and chemical processes, as well as the changes accompanying diagenesis and metamorphism.The precipitation of Fe did not stop during the sedimentation in an island arc related tectonic setting. The BIF strongly lacks the signatures from hydrothermal input. The presence of positive cerium anomalies and the absence of positive europium anomalies in the shaly banded ironformations imply that iron oxidation during BIF deposition took place in shallow waters rather than at depth, at oxicanoxic boundary. | Meenal Mishra | 2015 | Chinese Journal Of Geochemistry2015，34，3： | 1 |
| 10 | Thulium laser coagulation for venous malformations of glans penis显示文摘Vascular anomalies of the glans penis are very uncommon and have a sparse mention in the literature[1e3].Nd:YAG laser has been mentioned as a treatment of choice[3].The thulium laser has not been reported for its use till date.We describe a patient of venous malformation(VM)of the glans penis treated by us with the thulium laser. | Sanjay Kolte Parag Ingle Meenal Kolte Sonal Bhuyar | 2016 | Asian Journal of Urology2016，3，2： | 1 |
| 11 | Distinct Role of Core Promoter Architecture in Regulation of Light-Mediated Responses in Plant Genes显示文摘在现在的学习,我们选择了调整光的倡导者的四个不同的类。bedistinctly 组织进任何一个 TATA-box-containing 或 TATA 少些的调整光的倡导者罐头(包含开始者) 倡导者。进一步,使用本国的倡导者或他们核心 promoterelements 的交换版本,我们建立了元素有的那个 TATA 盒子和 Inr (开始者) 涉及调停光的规定的不同机制,和这些元素是 notswappable。我们鉴别在功能的 TATA 盒子或 Inr 元素的变化导致 nucleosomal 结构的形成。在在 Arabidopsis 生态型的 TATA 盒子或 Inr 元素的核苷酸差异建议在核心倡导者的核苷酸变化能改变基因表示。我们显示出那主题 overrepresentationin 激活光的倡导者包含下游地在场的不同特定的规章的主题 TSS (抄写 startsite ) ,和这力量在调整与这些元素平行的轻倡导者用作一个关键因素。最后,我们断定 TATA 盒子或 Inr 元素不清楚地在隔离,而是我们的结果行动与 TATA 盒子或 Inr 元素在同时发生建议另外的不同核心 promoterelements 的可能的参与给予选择到调停光的 transcription.Key 词: | Rakesh Srivastava Krishan Mohan Rai Meenal Srivastava Verandra Kumar Bindu Pandey Sudhir P. Singh Sumit K. Bag Brahma Deo Singh Rakesh Tuli Samir V. Sawant | 2014 | Molecular Plant2014，7，4： | 1 |
| 12 | Microbial remediation of nitroaromafic compounds:An overview显示文摘 | Meenal K Ambalal C | 2007 | Journal of Environmental Management2007，85，： | 1 |
| 13 | 显示文摘 | Meenal R S Bhattachrya S Chatterjee R | 2010 | Materials Science and Engineering B2010，171，： | 1 |
| 14 | Symptomatic pancreatic sarcoidosis显示文摘 | Meenal Shukla Muhammad F Hassan Vajinder Toor | 2007 | JOP J Pancreas(Online)2007，8，6： | 1 |
| 15 | Synthesis of Ag/AgCl-mesoporous silica nanocomposites using a simple aqueous solution-based chemical method and a study of their antibacterial activity on E. coli显示文摘Simple aqueous solution-based chemical methods have been developed for the synthesis of Ag/AgCl nanoparticle-mesoporous silica nanocomposites. Ag loading in the mesoporous silica was accomplished using a wet-impregnation method. The AgCl-mesoporous silica nanocomposite material(AgCl-mSi) was synthesized by using a 'one pot' method. Synthesized materials were characterized using X-ray diffraction,N2 adsorption-desorption analysis and high-resolution transmission electron microscopy. Antibacterial activity of the synthesized materials was investigated against Escherichia coli(E. coli) using the conventional plate-count method. All the materials showed high antibacterial activity even when the percentage loading of Ag in the nanocomposite was as low as 10 wt%. | Bhanudas Naik Vilas Desai Meenal Kowshik Vadakkethonippurathu Sivankutty Prasad Gerard Franklyn Fernando Narendra Nath Ghosh | 2011 | Particuology2011，9，3： | 1 |
| 16 | Effect of sunset yel- lowon testis in rats显示文摘 | NEERA M V MEENAL M RICHA K J | 2005 | Ecophysiol Occup Health2005，5，12： | 1 |
| 17 | Enhanced Expression of Rabies Virus Surface G-Protein in Escherichia coli using SUMO Fusion显示文摘 | Ankit Singh Dinesh Yadav Krishan Mohan Rai Meenal Srivastava Praveen C. Verma Pradhyumna K. Singh Rakesh Tuli | 2012 | The Protein Journal2012，，1： | 1 |
| 18 | Aggressive parenteral nutrition in sick very low birth weight babies: A randomized controlled trial显示文摘 | Amit Tagare Meenal Walawalkar Umesh Vaidya | 2013 | Indian Pediatrics2013，，10： | 1 |
| 19 | Microbial remediation of nitro-aromatic compounds: An overview显示文摘 | Meenal Kulkarni Ambalal Chaudhari | 2007 | Journal of Environmental Management2007，，2： | 1 |
| 20 | Biodegradation of p -nitrophenol by P. putida显示文摘 | Meenal Kulkarni Ambalal Chaudhari | 2005 | Bioresource Technology2005，，8： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员