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| 1 | Bone mineral density and disorders of mineral metabolism in chronic liver disease显示文摘AIM:To estimate the prevalence and identify the risk factors for metabolic bone disease in patients with cirrhosis.METHODS:The study was performed on 72 Indian patients with cirrhosis(63 male, 9 female;aged < 50 years).Etiology of cirrhosis was alcoholism(n = 37), hepatitis B(n = 25) and hepatitis C(n = 10).Twenty-three patients belonged to Child class A, while 39 were in class B and 10 in class C.Secondary causes for metabolic bone disease and osteoporosis were ruled out.Sunlight exposure, physical activity and dietary constituents were calculated.Complete metabolic profiles were derived, and bone mineral density(BMD) was measured using dual energy X ray absorptiometry.Low BMD was defined as a Z score below-2.RESULTS:Low BMD was found in 68% of patients.Lumbar spine was the most frequently and severely affected site.Risk factors for low BMD included low physical activity, decreased sunlight exposure, and low lean body mass.Calcium intake was adequate, with unfavorable calcium:protein ratio and calcium:phosphorus ratio.Vitamin D deficiency was highly prevalent(92%).There was a high incidence of hypogonadism(41%).Serum estradiol level was elevated significantly in patients with normal BMD.Insulin-like growth factor(IGF) 1 and IGF binding protein 3 levels were below the age-related normal range in both groups.IGF-1 was signiflcantly lower in patients with low BMD.Serum osteocalcin level was low(68%) and urinary deoxypyridinoline to creatinine ratio was high(79%), which demonstrated low bone formation with high resorption.CONCLUSION:Patients with cirrhosis have low BMD.Contributory factors are reduced physical activity, low lean body mass, vitamin D def iciency and hypogonadism and low IGF-1 level. | Joe George Hosahithlu K Ganesh Shrikrishna Acharya Tushar R Bandgar Vyankatesh Shivane Anjana Karvat Shobna J Bhatia Samir Shah Padmavathy S Menon Nalini Shah | 2009 | World Journal of Gastroenterology2009，15，28： | 15 |
| 2 | Integrated Guidance and Control of Moving-mass Actuated Kinetic Warheads显示文摘 | Menon K P Sweriduk D G Ohlmeyer E J Malyevac S D | 2004 | Journal of Guidance Control and Dynamics January-February 20042004，27，1： | 1 |
| 3 | Progress and challenges in screening for early detection of ovarian cancer显示文摘 | JACCOBS I J MENON U | 2004 | Mol Cell Proteomics2004，3，4： | 1 |
| 4 | Shear-modulusestimation by application of spatially-modulated impulsive acoustic radiation force显示文摘 | McAleavey SA Menon M Orszulak J | | 0，，： | 1 |
| 5 | Screening for ovarian cancer显示文摘 | Rosenthal A N Menon U Jacobs I J | 2006 | Clin Obstet Gynecol2006，49，3： | 1 |
| 6 | Establishing a human chorionic gonadotropin cutoff to guide methotrexate treatment of ectopic pregnancy: u systematic review 显示文摘 | Menon S Colins J Barnhart KT | 2007 | Fertil Steril2007，87，： | 1 |
| 7 | Patient-cen- tered care for Muslim women:Provider and patient per- spectives显示文摘 | Hasnain M Connell K J Menon U | 2011 | J Womens Health (Larchmt)2011，20，1： | 1 |
| 8 | Synthesis and study of binuclear calix arene Schiff base Co(II)complexes as catalyst in the presence of PhIO for the catalytic oxidation of olefin显示文摘 | PATEL R V PANCHAL J G MENON S K | 2010 | J Incl Phenom Macrocycl Chem2010，67，12： | 1 |
| 9 | Temperature de- pendence of the electrical conductivity of imidazolium ionic liquids 显示文摘 | LEYS J W1DBBENHORST M MENON C P | 2008 | J Chem Phys2008，128，06： | 1 |
| 10 | Climate effects of black carbon aerosols in China and India 显示文摘 | Menon S Hansen J Nazarenko L | 2002 | Science2002，297，5590： | 1 |
| 11 | 1,25 -Dihydmxyvitamin D de- ficiency is associated with preterm birth in Mriean American and cauca- sian women显示文摘 | Thota C Menon R Fortunato S J | 2014 | Reprod Sei2014，21，2： | 1 |
| 12 | Climate effects of black carbon aerosols in China and India显示文摘 | MENON S HANSEN J NAZARENKO L | 2002 | Science2002，297，5590： | 1 |
| 13 | Enoloscopic carpal tunnel release:a single portal technigue显示文摘 | Menon J | 1993 | Contemp Orthopald1993，26，2： | 1 |
| 14 | Activity and Characterization of Cu/Zn, Cu/Cr and Cu/Zr on Alumina For Methanol Reforming for Fuel Cell Vehicles显示文摘 | Bard Lindstrom Lars J Pettersson Govind Menon P | 2002 | Applied Catalysis A : General2002，234，： | 1 |
| 15 | Regulation of LH receptor mRNA binding protein by miR-122 in rat o-varies 显示文摘 | Menon B Sinden J Franzo-Romain M | 2013 | Endocrinology2013，154，12： | 1 |
| 16 | Universal total wrist implant: experience with a carpal ~omponent fixed with three screws 显示文摘 | Menon J | 1998 | J Arthroplasty1998，13，5： | 1 |
| 17 | 接受最佳治疗的高危血管病患者中C反应蛋白对脂蛋白(a)相关心血管病风险的影响显示文摘脂蛋白(a)是动脉粥样硬化性心血管病的遗传致病危险因素,但目前还不清楚哪些动脉粥样硬化性心血管病患者从脂蛋白(a)降低中受益最大。在二级预防中炎症是否会调节与脂蛋白(a)相关的心血管病风险也未知。该文旨在确定在接受最佳治疗的高危心血管病患者中,脂蛋白(a)相关的心血管病风险是否受到全身炎症的调节。 | 周卫(译) 刘莉(摘/审校) Puri R Nissen SE Arsenault BJ St John J Riesmeyer JS Ruotolo G McErlean E Menon V Cho L Wolski K Lincoff AM Nicholls SJ | 2020 | 中华高血压杂志2020，28，11： | 1 |
| 18 | Diffusing wave spectroscopy of dynamics in a three dimensional granular flow显示文摘 | N MENON D J DURIAN | 1920 | Science1920，1997，： | 1 |
| 19 | Organochlorine pesticides and PCBs in a southern Atlantic coastal lagoon watershed, Argentina显示文摘 | Menone M L Aizpun de Moreno J E Moreno V J | 2001 | Arch Environ Con- tam Toxicol2001，40，3： | 1 |
| 20 | Inflammatory cytokine ( interleukine-1,6, and 8 and tumor necrosis factor-α) release from cultured human fetal membranes in response to endotoxin lipopoly saccharide mirrors amniotic fluid concentrations 显示文摘 | Sephen J Fortunato R P Menon K F | 1996 | Am J Obstet Gynecol1996，174，6： | 1 |
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