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| 1 | Lactoferrin Levels in the Gastric Tissue of Helicobacter pylori -Positive and -Negative Patients and Its Effect on Anemia显示文摘 | Ya?ar Do?an Tülay Erkan Zerrin ?nal Merve Usta Gülen Do?usoy Fügen ?ullu ?oku?ra? Tufan Kutlu Helieh S. Oz | 2012 | Mediators of Inflammation2012,,: | 1 |
| 2 | Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana显示文摘 | George G M van der Merve M J Nunes-Nesi A | | 0,,01: | 1 |
| 3 | Biodegradable non-aromatic adhesive pol- yurethanes based on disaccharides formedical applications显示文摘 | BURHAN A SULEYMAN K MERVE G | 2014 | International Journal ofAd- hesion & Adhesives2014,,49: | 1 |
| 4 | Clinical and genetic characteristics of retinoblastoma patients in a single center with four novel RB1 variants显示文摘AIM:To assess the clinical and genetic characteristics of children diagnosed with retinoblastoma(RB)at Gazi University Faculty of Medicine’s Department of Pediatric Oncology.METHODS:All cases diagnosed with RB and received treatment and follow-up in the Ophthalmology and Pediatric Oncology Department,October 2016 to May 2021 were evaluated retrospectively.The RB1 gene was analyzed by next-generation sequencing(NGS)technique in DNAs obtained from peripheral blood samples of the patients.RESULTS:This study included 53 cases with 67 RBaffected eyes during the study period.The mean age was 24.6(median:18.5,range:3–151)mo.There were 15(22.3%)Group D eyes and 39(58.2%)Group E eyes.The RB1 gene was sequenced by the NGS method in 19 patients.Heterozygous RB1:NM_000321.3:c.54_76del(p.Glu19AlafsTer4)variant was detected in a 15-month-old female with bilateral RB.Heterozygous RB1:NM_000321.3:c.1814+3A>T variant was detected in a 5.5-month-old male with bilateral RB.The intronic RB1:NM_000321.3:c.1332+4A>G variant was detected in patient 14,a 13-month-old male with unilateral RB.The RB1:NM_000321.3:c.575_576del(p.Lys192SerfsTer10)variant was found in an 18-month-old female with an allele frequency of 37%.These variants have not been reported in the literature and mutation databases.CONCLUSION:Four novel variants are described and one of them is found in two different patients.This data is crucial for assessing prognosis.It serves as a guide for estimating the long-term risk of secondary malignancy as well as the short-term risk of developing additional malignancies in the same eye and the other eye. | Özge Vural Hatice Tuba Atalay Gulsum Kayhan Bercin Tarlan Merve Oral Arzu Okur Faruk GüçlüPınarlı Ceyda Karadeniz | 2023 | International Journal of Ophthalmology(English edition)2023,16,8: | 1 |
| 5 | Naringin attenuates oxidative stress,inflammation,apoptosis,and oxidative DNA damage in acrylamide-induced nephrotoxicity in rats显示文摘Objective:To explore the possible effects of naringin on acrylamide-induced nephrotoxicity in rats.Methods:Sprague-Dawley rats weighing 200-250 g were randomly divided into five groups.The control group was given intragastric(i.g.)saline(1 mL)for 10 d.The acrylamide group was given i.g.acrylamide in saline(38.27 mg/kg titrated to 1 mL)for 10 d.The treatment groups were administered with naringin in saline(50 and 100 mg/kg,respectively)for 10 d and given i.g.acrylamide(38.27 mg/kg)1 h after naringin injection.The naringin group was given i.g.naringin(100 mg/kg)alone for 10 d.On day 11,intracardiac blood samples were obtained from the rats when they were under anesthesia,after which they were euthanized.Urea and creatinine concentrations of blood serum samples were analyzed with an autoanalyzer.Enzyme-linked immunosorbent assay was used to quantify malondialdehyde,superoxide dismutase,glutathione,glutathione peroxidase,catalase,tumor necrosis factor-α,nuclear factor-κB,interleukin(IL)-33,IL-6,IL-1β,cyclooxygenase-2,kidney injury molecule-1,mitogen-activated protein kinase-1,and caspase-3 in kidney tissues.Renal tissues were also evaluated by histopathological and immunohistochemical examinations for 8-OHdG and Bcl-2.Results:Naringin attenuated acrylamide-induced nephrotoxicity by significantly decreasing serum urea and creatinine levels.Naringin increased superoxide dismutase,glutathione,glutathione peroxidase,and catalase activities and decreased malondialdehyde levels in kidney tissues.In addition,naringin reduced the levels of inflammatory and apoptotic parameters in kidney tissues.The histopathological assay showed that acrylamide caused histopathological changes and DNA damage,which were ameliorated by naringin.Conclusions:Naringin attenuated inflammation,apoptosis,oxidative stress,and oxidative DNA damage in acrylamide-induced nephrotoxicity in rats. | Volkan Gelen Serkan Yıldırım EminŞengül AliÇınar FikretÇelebi Merve Küçükkalem Melahat Gök | 2022 | Asian Pacific Journal of Tropical Biomedicine2022,12,5: | 1 |
| 6 | Chemical composition, antimicrobial, insecticidal, phytotoxic and antioxidant activities of Mediterranean Pinus brutia and Pinus pinea resin essential oils显示文摘Essential oils of the resins of Pinus brutia and Pinus pinea were evaluated for their biological potential. Essential oils were characterized using GC-MS and GC/FID. In vitro antimicrobial, phytotoxic, antioxidant, and insecticidal activities were carried out using the direct contact and the fumigant assays, respectively. The chemical profile of the essential oils of the resins of P. pinea and P. brutia included mainly α-pinene(21.39% and 25.40%), β-pinene(9.68% and 9.69%), and caryophyllene(9.12% and 4.81%). The essential oils of P. pinea and P. brutia exerted notable antimicrobial activities on Micrococcus luteus and Bacillus subtilis, insecticidal activities on Ephestia kuehniella eggs, phytotoxic activities on Lactuca sativa, Lepidium sativum, and Portulaca oleracea, as well as antioxidant potential. Indications of the biological activities of the essential oils suggest their use in the formulation of ecofriendly and biocompatible pharmaceuticals. | ULUKANLI Zeynep KARABRKLü Salih BOZOK Fuat ATES Burhan ERDOGAN Selim CENET Menderes KARAASLAN Merve Gksin | 2014 | Chinese Journal of Natural Medicines2014,12,12: | 1 |
| 7 | Metabolic engineering of Saccharomyces cerevisiae for the synthes of the wine-related antioxidant resveratrol显示文摘 | Becker V J Armstrong O G Merve J M | 2003 | FEMS Yeast reasearch2003,4,1: | 1 |
| 8 | Traffic sign recognition using scale invariant feature transform and color classification 显示文摘 | MERVE C K MUHITTIN G SIMA E U | 2008 | International Symposium on Computer and Information Sciences2008,,: | 1 |
| 9 | Clinical characteristics and outcomes of nosocomial COVID-19 in Turkey:A retrospective multicenter study显示文摘Objective:To identify the clinical characteristics and outcomes of hospital-acquired SARS-CoV-2 infection during the vaccination period nationwide in Turkey.Methods:COVID-19 patients followed in the pandemic services across Turkey between January 1,2021,and March 31,2022 were investigated retrospectively.Nosocomial COVID-19 was defined as a patient neither diagnosed with COVID-19 nor suspected COVID-19 at the hospital admission and was confirmed COVID-19≥5 days after hospital admission.The primary outcome of this study was in-hospital mortality;demographic features and vaccination status was compared between survivors and non-survivors.Results:During the study period,15573 COVID-19 patients were followed in 18 centers and 543(3.5%)patients were nosocomial COVID-19.Most patients with nosocomial COVID-19(80.4%)were transferred from medical wards.162(29.8%)of the patients with nosocomial COVID-19 admitted to the intensive care unit due to disease severity and 138(25.4%)of the patients died during hospital stay.Advanced age(≥65 years)and number of comorbid diseases(≥2)was found to be associated with mortality in nosocomial COVID-19(OR 1.74,95%CI 1.11-2.74 and OR 1.60,95%CI 1.02-2.56,respectively).Vaccination was associated with survival in nosocomial COVID-19(OR 0.25,95%CI 0.16-0.38).Conclusions:Patients with nosocomial COVID-19 had increased admission to intensive care units and higher mortality rate.Vaccination can decrease the in-hospital mortality rate. | Süleyman Yıldırım Celalettin Yılmaz Gülru Polat Serap Argun Baris İlknur Başyiğit İlknur Kaya Ceyda Anar Mihriban Bozkurt HüsnüBaykal Hulya Dirol Gamzenur Ozbey Emine Ozsari Emel Cireli Ali KadriÇırak Dursun Tatar Mine Gayaf Selen Karaoglanoglu Yener Aydin Atilla Eroglu Yıldız Olçar Berna Botan Yıldırım Bengül Gürsoy Deniz Demir Yılmaz Elif Yelda Ozgun Niksarlioglu Ramazan Eren Ayşegül Tomruk Erdem Müge Meltem Tor Fusun Fakili MustafaÇolak Merve Erçelik Ali Tabaru Özlem Ediboglu | 2023 | Asian Pacific Journal of Tropical Medicine2023,16,8: | 0 |
| 10 | Telenutrition for the management of inflammatory bowel disease:Benefits,limits,and future perspectives显示文摘Patients with inflammatory bowel disease(IBD)require lifelong and personalized care by a multidisciplinary healthcare team.However,the traditional medical model is not ideal for patients who require continuous close monitoring and whose symptoms may dramatically worsen between regularly scheduled visits.Additionally,close dietary follow-up and monitoring of IBD in a traditional setting are challenging because of the disease complexity,high pressure on outpatient clinics with a small number of IBD specialist dietitians,and rising incidence.Given the significant burden of IBD,there is a need to develop effective dietary management strategies.The coronavirus disease 2019 pandemic caused an unprecedented shift from in-person care to delivering health care via technological remote devices.Traditional nutrition therapy and consultation can be provided by telenutrition through remote electronic communication applications that could greatly benefit patient care.Telenutrition might be useful,safe,and cost-effective compared with standard care.It is likely that virtual care for chronic diseases including IBD will continue in some form into the future.This review article summarizes the evidence about telenutrition applications in the management of IBD patients,and we gave an overview of the acceptance and impact of these interventions on health outcomes. | Merve Güney Coşku Ezgi Kolay Metin Basaranoglu | 2023 | World Journal of Clinical Cases2023,11,2: | 0 |
| 11 | Radiative suppression of exciton-exciton annihilation in a two-dimensional semiconductor显示文摘Two-dimensional(2D)semiconductors possess strongly bound excitons,opening novel opportunities for engineering light-matter interaction at the nanoscale.However,their in-plane confinement leads to large non-radiative exciton–exciton annihilation(EEA)processes,setting a fundamental limit for their photonic applications.In this work,we demonstrate suppression of EEA via enhancement of light-matter interaction in hybrid 2D semiconductor-dielectric nanophotonic platforms,by coupling excitons in WS2 monolayers with optical Mie resonances in dielectric nanoantennas.The hybrid system reaches an intermediate light-matter coupling regime,with photoluminescence enhancement factors up to 102.Probing the exciton ultrafast dynamics reveal suppressed EEA for coupled excitons,even under high exciton densities>10^(12)cm^(−2).We extract EEA coefficients in the order of 10^(−3),compared to 10^(−2)for uncoupled monolayers,as well as a Purcell factor of 4.5.Our results highlight engineering the photonic environment as a route to achieve higher quantum efficiencies,for low-power hybrid devices,and larger exciton densities,towards strongly correlated excitonic phases in 2D semiconductors. | Luca Sortino Merve Gülmüs Benjamin Tilmann Leonardo de S.Menezes Stefan A.Maier | 2023 | Light(Science & Applications)2023,12,9: | 0 |
| 12 | Cylinder Pressure Prediction of An HCCI Engine Using Deep Learning显示文摘Engine tests are both costly and time consuming in developing a new internal combustion engine.Therefore,it is of great importance to predict engine characteristics with high accuracy using artificial intelligence.Thus,it is possible to reduce engine testing costs and speed up the engine development process.Deep Learning is an effective artificial intelligence method that shows high performance in many research areas through its ability to learn high-level hidden features in data samples.The present paper describes a method to predict the cylinder pressure of a Homogeneous Charge Compression Ignition(HCCI)engine for various excess air coefficients by using Deep Neural Network,which is one of the Deep Learning methods and is based on the Artificial Neural Network(ANN).The Deep Learning results were compared with the ANN and experimental results.The results show that the difference between experimental and the Deep Neural Network(DNN)results were less than 1%.The best results were obtained by Deep Learning method.The cylinder pressure was predicted with a maximum accuracy of 97.83%of the experimental value by using ANN.On the other hand,the accuracy value was increased up to 99.84%using DNN.These results show that the DNN method can be used effectively to predict cylinder pressures of internal combustion engines. | Halit Yaşar GültekinÇağıl Orhan Torkul MerveŞişci | 2021 | Chinese Journal of Mechanical Engineering2021,34,2: | 0 |