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| 1 | Frequency and prognostic role of mucosal healing in patients with Crohn's disease and ulcerative colitis after one-year of biological therapy显示文摘AIM:To assess the endoscopic activity before and after a one-year period of biological therapy and to evaluate the frequency of relapses and need for retreatment after stopping the biologicals in patients with Crohn’s disease(CD)and ulcerative colitis(UC).METHODS:The data from 41 patients with CD and 22 patients with UC were assessed.Twenty-four CD patients received infliximab,and 17 received adalimumab.The endoscopic severity of CD was quantified with the simplified endoscopic activity score for Crohn’s disease in CD and with the Mayo endoscopic subscore in UC.RESULTS:Mucosal healing was achieved in 23 CD and7 UC patients.Biological therapy had to be restarted in78%of patients achieving complete mucosal healing with CD and in 100%of patients with UC.Neither clinical remission nor mucosal healing was associated with the time to restarting the biological therapy in either CD or UC.CONCLUSION:Mucosal healing did not predict sustained clinical remission in patients in whom the biological therapies had been stopped. | Klaudia Farkas Péter László Lakatos Mónika Szcs va Pallagi-Kunstár Anita Bálint Ferenc Nagy Zoltán Szepes Noémi Vass Lajos S Kiss Tibor Wittmann Tamás Molnár | 2014 | World Journal of Gastroenterology2014，20，11： | 2 |
| 2 | Synthesis and characterization of a novel thermo-sensitive copolymer of N-isopropylacrylamide and dibenzo- 18-crown-6-diacrylamide显示文摘 | Ju X J Chu L Y Mi P | 2006 | Macromolecular Rapid Communications2006，27，24： | 1 |
| 3 | Multi-scale fractal dimension based on morphological covering for gear fault diagnosis显示文摘 | LI B ZHANG P L MI S S | 2011 | Journal of Mechanical Engineering2011，225，9： | 1 |
| 4 | 查看详情显示文摘 | Mi L Xu P Wang P N | | 0，，： | 1 |
| 5 | The cloning and expression of a novel rPDCD5 gene from rice显示文摘 | MI L P WEI C HUANG J S | 2004 | Yi Chuan2004，26，6： | 1 |
| 6 | Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence显示文摘 | Brodin P Majlessi L de Jonge MI | 2006 | Infect Immun2006，74，： | 1 |
| 7 | Oxygen reduction behavior with silver alloy catalyst in alkaline media 显示文摘 | Hong K L Joong P S Mi J S | 1996 | Materials Chemistry and Physics1996，45，3： | 1 |
| 8 | Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China显示文摘 | Wang J H Chen W L Li J M Wu S F Chen T L Zhu Y M Zhang W N Li Y Qiu Y P Zhao A H Mi J Q Jie J Wang Y G Ma Q L Huang H Wu D P Wang Q R Li Y Yan X J Yan J S Li J Y Wang S Huang X J Wang B S Jia W Shen Y Chen Z Chen S J | 2013 | Proceedings of the National Academy of Sciences2013，110，17： | 1 |
| 9 | Luminescence characteristics of yellow emitting Ba3SiO5:Eu2+ phosphor显示文摘 | Joung k p Mi A L Kyoung J C | 2005 | J Mater Sci2005，，40： | 1 |
| 10 | Effects of dietary mulberry, Korean red ginseng and banaba on glucose homeostasis in relation to PPAR-α, PPAR-γ, and LPL mRNA expressions 显示文摘 | Mi Y P K S L Mi K S | 2005 | Life Sciences2005，77，26： | 1 |
| 11 | Atypical antipsychotic agents in the treatment of violent patients with schizophrenia and schizoaffective disorder显示文摘 | Krakowski MI Czobor P Citrome L | | 0，，06： | 1 |
| 12 | Prediction ofglobal vapor-liquid equilibria for mixtures containing polarand associating components with improved renormalizationgroup theory 显示文摘 | MI J G TANG Y P ZHONG C L | 2005 | Physical Chemistry: Ser B2005，109，20： | 1 |
| 13 | Histopathologic features and risk factors for benignity, hyperplasia, and cancer in endometrial polyps显示文摘 | SAVELLI L DE IACO P SANTI MI D | 2003 | Am J Obstet Gynecol2003，4，： | 1 |
| 14 | Improved optical response for N- doped anatase TiO2 films prepared by pulsed laser deposition in N2/NH3/O2 mixture显示文摘 | Xu P Mi L Wang P N | 2006 | Journal of Crystal Growth2006，289，2： | 1 |
| 15 | Friction and wear properties of short carbon fiber reinforced aluminum matrix composites 显示文摘 | Liu L Li W Mi Tang Y P | 2009 | Wear2009，，266： | 1 |
| 16 | Functional analysis of early secreted antigenic target-6,the dominant T-cell antigen of Mycobacterium tuberculosis,reveals key residues involved in secretion,complex formation,virulence,and immunogenicity显示文摘 | Brodin P de Jonge MI Majlessi L | 2005 | J Biol Chem2005，280，33： | 1 |
| 17 | Comparison of the killing effects between nitrogen- doped and pure TiO2 on HeLa cells with visible light irradiation显示文摘 | Li Z Pan X B Wang T L Wang P N Chen J Y Mi L | 2013 | Nanoscale Res Lett2013，8，： | 1 |
| 18 | Immuno-detection of Staphylococcus aureus biofilm on a cochlear implant显示文摘 | Kos MI Stenz L Francois P | 2009 | Infection2009，37，5： | 1 |
| 19 | Involvement of calcitonin gene-related peptide innervation in the promoting effect of low-intensity pulsed ultrasound on spinal fusion without decortication显示文摘 | Wang X Y Guo X Cheng J C Mi Y L Lai P Y | 2010 | Spine (Phila Pa 1976)2010，35，： | 1 |
| 20 | Atypical antipsychotic agents in the treatment of violent patients with schizophrenia and schizoaffective disorder显示文摘 | Krakowski MI Czoisor P Citrome L | 2006 | Arch Gen Psychiatry2006，63，6： | 1 |
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