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| 1 | Association of homocysteine and smoking with cerebral microemboli in patients with mechanical heart valves:a transcranial Doppler study显示文摘Objectives Microembolic signals(MES)on transcranial Doppler(TCD)predict stroke and cognitive decline.Plasma levels of total homocysteine(tHcy),a prothrombotic factor,are higher in patients with microemboli in carotid stenosis and in patients with paradoxical embolism.In this study we assessed the association between the level of tHcy and the number of MES in patients with mechanical heart valves(MHVs).Methods TCD monitoring was performed to detect MES before and after breathing 100% oxygen and repeated every 2-4 weeks up to six times.results Twenty-five patients with MHVs(mean age:63.60±10.15 years)participated in this study;15 were men(66.47±7.25 years)and 10 were women(59.30±12.60 years).In total,there were 126 study visits.In multiple regression,higher tHcy was associated with more MES in both preoxygenation(OR 1.34(95%CI 1.07 to 1.68,P=0.009))and postoxygenation(OR 1.40(95% CI 1.07 to 1.83,P=0.01))phases.Current smoking and the length of time between the operation and monitoring also correlated with a higher number of MES before and after breathing oxygen,particularly in women.conclusions Higher tHcy and smoking were associated with a higher MES count in both preoxygenation and postoxygenation phases.Because smoking can be stopped and hyperhomocysteinaemia is treatable,these are clinically important findings. | Alicia Mattia M Reza Azarpazhooh Claudio Munoz Chrysi Bogiatzi Mackenzie A Quantz J David Spence | 2017 | Stroke & Vascular Neurology2017，2，4： | 2 |
| 2 | Hardness equation for ormosils 显示文摘 | Makishima A Mackenzie J D | 2000 | Journal of Sol-Gel Science and Technology2000，19，： | 1 |
| 3 | Dolomite formation and biochemical cycles in the Phanerozoic显示文摘 | Burns S J MacKenzie J A Vasconcelos C | 2000 | Sedimentology2000，47，1： | 1 |
| 4 | The origin of lead in the organic horizon of tundra soils: atmospheric deposition,plant translocation from the mineral soil or soil mineral mixing 显示文摘 | KIAMINDER J FARMER J G MACKENZIE A B | 2011 | Science of the Total Environment2011，409，20： | 1 |
| 5 | The composition range of alumino silicate geopolymers显示文摘 | Fletcher R A Mackenzie K J D Nieholson C L | 2005 | J Eur Ceram Soc2005，25，： | 1 |
| 6 | Salt tolerance of soybean vari- eties during germination and later growth 显示文摘 | Abel G H Mackenzie A J | 1964 | Crop Sci- ence1964，，4： | 1 |
| 7 | On the mechanisms of duetile failure in high-strength steels subjected to multi-axial stress-states显示文摘 | HANCOCK J MACKENZIE A | 1976 | Journal of the Mechanics and Physics of Solids1976，24，： | 1 |
| 8 | Quantitative gas chromatography-mass spectrometry analysis of geological samples显示文摘 | Rullkotter J Mackenzie A S Welte D H | 1983 | Advances in Organic Geochemistry1983，，： | 1 |
| 9 | Long - term physical impairment and functional outcomes after complex facial fractures 显示文摘 | Girotto J A MacKenzie E Fowler C | 2001 | Plast Reconstr Surg2001，108，2： | 1 |
| 10 | On the influence of state of stress on ductile failure initiation in high strength steels显示文摘 | MACKENZIE A HANCOCK J W BROWN D K | 1977 | Engineering Fracture Mechanics1977，9，： | 1 |
| 11 | Salt tolerance of soybean varieties during germination and later growth显示文摘 | Abel G H Mackenzie A J | 1964 | Crop Sci1964，4，： | 1 |
| 12 | Glycosynthases: mutant glycosidases for oligosaccharide synthesis 显示文摘 | Mackenzie L F Wang Q Warren R A J | 1998 | Journal of the American Chemical Society1998，120，22： | 1 |
| 13 | Molecular parameters of maturation in the Toarcian shales,Paris,France Ⅰ:changes in the configuration of the acyclic isoprenoid alkanes,steranes and triterpanes显示文摘 | Mackenzie A S Patience R L Maxwell J R | 1980 | Geochimica et Cosmochimica Acta1980，44，： | 1 |
| 14 | Impact of soil management systems on organic dwarf apple orchards and soil aggregate stability, bulk density, temperature and water content 显示文摘 | WALSH B D SALMINS S BUSZARD D J MACKENZIE A F | 1996 | Canadian Journal of Soil Science1996，76，2： | 1 |
| 15 | Transparent silica gel-PMMA composites显示文摘 | Pope E J A A Sami M Mackenzie J D | 1989 | J Mater Res1989，，4： | 1 |
| 16 | Economics of CO2 capture using the calcium cycle with a pressurized fluidized bed combustor 显示文摘 | MACKENZIE A GRANATSTEIN D L ABANADES J C | 2007 | Energy & Fuels2007，21，2： | 1 |
| 17 | Nanoanalysis of very fine VN precipitates insteel显示文摘 | Mackenzie M Craven A J Collins C L | 2006 | Scipta Materialia2006，54，1： | 1 |
| 18 | Improved Moire interferometry and applications in fracture mechanics, residual stress and damaged composites 显示文摘 | McDonach A McKelvie J MacKenzie P M | 1983 | Exp Tech1983，7，6： | 1 |
| 19 | Increased Sensi- tivity of the Rapid Hydrophobic Grid Membrane Filter Enzyme- Labeled Antibody Procedure for Eschcrichia coli O157 Detection in Foods and Bovine Feces显示文摘 | Szabo R A Todd E C D Mackenzie J M | 1990 | Applied and Environmental Mi- crobiology1990，56，11： | 1 |
| 20 | Preparation and characterisation of fly ash based geopolymer mortars 显示文摘 | Temuujin J van Riessen A MacKenzie K J D | 2010 | Construction and Building Materials2010，24，10： | 1 |
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