|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Liver zonation: Novel aspects of its regulation and its impact on homeostasis显示文摘Liver zonation,the spatial separation of the immense spectrum of different metabolic pathways along the liver sinusoids,is fundamental for proper functioning of this organ.Recent progress in elucidating localization and interactions of different metabolic pathways by using'omics'techniques and novel approaches to couple them with refined spatial resolution and in characterizing novel master regulators of zonation by using transgenic mice has created the basis for a deeper understanding of core mechanisms of zonation and their impact on liver physiology,pathology and metabolic diseases.This review summarizes the fascinating technical achievements for investigating liver zonation and the elucidation of an emerging network of master regulators of zonation that keep the plethora of interrelated and sometimes opposing functions of the liver in balance with nutritional supply and specific requirements of the entire body.In addition,a brief overview is given on newly described zonated functions and novel details on how diverse the segmentation of metabolic zonation may be.From these facts and developments a few fundamental principles are inferred which seem to rule zonation of liver parenchyma.In addition,we identify important questions that still need to be answered as well as interesting fields of research such as the connection of zonation with circadian rhythm and gender dimorphism which need to be pushed further,in order to improve our understanding of metabolic zonation.Finally,an outlook is given on how disturbance of liver zonation and its regulation may impact on liver pathology and the development of metabolic diseases. | Rolf Gebhardt Madlen Matz-Soja | 2014 | World Journal of Gastroenterology2014，20，26： | 2 |
| 2 | Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity显示文摘Dear Editor,Next-generation sequencing revealed that the majority of the human genome is transcribed but has no coding function.It is estimated that.30000 long noncoding RNAs(lncRNAs)are expressed in humans,but their functions are largely unknown(Suckau et al.,2009;Rinn and Chang,2012;Poller et al.,2013).Consideration of noncoding genomic elements in pathogenetic studies is warranted and enabled by technological advances allowing comprehensive transcriptome mapping of protein-coding genes as well as small and long ncRNAs. | Martina Gast Blanche Schroen Antje Voigt Jan Haas Uwe Kuehl Dirk Lassner Carsten Skurk Felicitas Escher Xiaomin Wang Adelheid Kratzer Katharina Michalik Anna Papageorgiou Tim Peters Madlen Loebel Sabrina Wilk Nadine Althof Kannanganattu VPrasanth Hugo Katus Benjamin Meder Shinichi Nakagawa Carmen Scheibenbogen Heinz-Peter Schultheiss Ulf Landmesser Stefanie Dimmeler Stephane Heymans Wolfgang Poller | 2016 | Journal of Molecular Cell Biology2016，8，2： | 2 |
| 3 | A real options evaluation model for the diffusion prospects of new renewable power generation technologies 显示文摘 | Knmbaroglu G Madlener R Demirel M | 2008 | Energy Economics2008，30，： | 1 |
| 4 | Induction of inducible nitric oxide synthase and its corresponding tetrahydrobiopterin-cofactor-synthesizing enzyme GTP-cyclohydrolase I during cutaneous wound repair显示文摘 | Frank S Madlener M Pfeilschifter J | 1998 | J Invest Dermatol1998，111，6： | 1 |
| 5 | Shaped Ceramics with Tunable Magnetic Properties from Metal-Containing Polymers 显示文摘 | MARK J M MADLEN G NElL C | 2000 | Science2000，287，5： | 1 |
| 6 | Economics of CCS for coal plants: Impact of investment costs and efficiency on market diffusion in Europe显示文摘 | Lohwasser R Madlener R | 2012 | Energy Economics2012，34，3： | 1 |
| 7 | Impacts of urbanization on urban structures and energy demand: what can we learn for ur- ban energy planning and urbanization management 显示文摘 | Reinhard Madlener Yasin Sunak | 2011 | Sustainable Cities and Society2011，1，1： | 1 |
| 8 | Impacts of Urbanization on Urban Structures and Energy Demand: What Can We Learn for Urban Energy Planning and Urbanization Management? 显示文摘 | Madlener R Sunak Y | 2011 | Sustainable Cities and Society2011，11，1： | 1 |
| 9 | Impacts of Urbanization on Urban Structures and Energy Demand : What Can We Learn for Urban Energy Planning and Urbanization Management? 显示文摘 | MADLENER R SUNAK Y | 2011 | Sustainable Cities and Society2011，1，1： | 1 |
| 10 | Leaf shape evolution through duplication, regulatory diversification, and loss of a homeobox gene显示文摘 | Daniela V Daniel K Madlen I R | 2014 | Science2014，343，： | 1 |
| 11 | Comparison of Three Patent Foramen Ovale Closure Devices in a Randomized Trial (Amplatzer Versus CardioSEAL-STARflex Versus Helex Occluder)显示文摘 | Margaret Taaffe Evelyn Fischer Andreas Baranowski Nicolas Majunke Corinna Heinisch Michaela Leetz Ralph Hein Yves Bayard Franziska Büscheck Madlen Reschke Ilona Hoffmann Nina Wunderlich Neil Wilson Horst Sievert | 2008 | The American Journal of Cardiology2008，，9： | 1 |
| 12 | Use of heparin during cardiopulmonary bypass in patients with a history of heparin-induced thrombocytopenia 显示文摘 | Potzseh B Klovekorn WP Madlener K | 2000 | N Engl J Med2000，343，： | 1 |
| 13 | Immunologic and bio- chemical effects of the fermented wheat germ extract Avemar 显示文摘 | lllmer C Madlener S Horvath Z | 2005 | Experimental biology and medicine2005，230，2： | 1 |
| 14 | Impacts of urbanization on urban structures and energy demand: what can we learn for urban energy planning and urbanization management显示文摘 | Madlener R Sunak Y | 2011 | Sustainable Cities and Society2011，，1： | 1 |
| 15 | Diagnostic utility of new immunoassays for the cardiac markers cTnI, myoglobin and CK-MB mass 显示文摘 | Weber M Rau M Madlener K | 2005 | Clin Biochem2005，38，11： | 1 |
| 16 | Gallic acid inhibits ribonucle- otide reductase and cyclooxygenases in human HL-60 promyeloeytic leukemia cells显示文摘 | Madlener S Illmer C Horvath Z | 2007 | Cancer Lett2007，245，12： | 1 |
| 17 | Econometric analysis of residential energy demand : a survey 显示文摘 | REINHARD MADLENER | 1996 | The Journal of En ergy Literature1996，11，2： | 1 |
| 18 | Impacts of urbanization on urban structures and energy demand: What can we learn for urban energy planning and urbanization management?显示文摘 | Reinhard Madlener Yasin Sunak | 2010 | Sustainable Cities and Society2010，，1： | 1 |
| 19 | Econometric analysis of residential energy demand: a survey显示文摘 | Madlener R | 1996 | The Journal of Energy Literature1996，11，2： | 1 |
| 20 | Impacts of urbanization on urban structures and energy demand: what can we learn for urban energy planningand urbaniza- tion management? 显示文摘 | MADLENER R SUNAK Y | 2011 | Sustainable Cities and Society2011，1，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员