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| 1 | From Bench to the Clinic: The Path to Translation of Nanotechnology-Enabled mRNA SARS-CoV-2 Vaccines显示文摘During the last decades,the use of nanotechnology in med icine has effectively been translated to the design of drug delivery systems,nanostructured tissues,diagnostic platforms,and novel nanomaterials against several human diseases and infectious pathogens.Nanotechnology-enabled vaccines have been positioned as solutions to mitigate the pandemic outbreak caused by the novel pathogen severe acute respiratory syndrome coronavirus 2.To fast-track the development of vaccines,unprecedented industrial and academic collaborations emerged around the world,resulting in the clinical translation of effective vaccines in less than one year.In this article,we provide an overview of the path to translation from the bench to the clinic of nanotechnology-enabled messenger ribonucleic acid vaccines and examine in detail the types of delivery systems used,their mechanisms of action,obtained results during each phase of their clinical development and their regulatory approval process.We also analyze how nanotechnology is impacting global health and economy during the COVID-19 pandemic and beyond. | Diana O.Lopez‑Cantu Xichi Wang Hector Carrasco‑Magallanes Samson Afewerki Xingcai Zhang Joseph V.Bonventre Guillermo U.Ruiz‑Esparza | 2022 | Nano-Micro Letters2022，14，3： | 2 |
| 2 | A randomized phase 3 trial comparing pemetrexed/carboplatin and docetaxel/carboplatin as first-line treatment for advanced,nonsquamous non-small cell lung cancer显示文摘 | Rodrigues-Pereira J Kim JH Magallanes M | | 0，，11： | 1 |
| 3 | Stability after laser in situ keratomileusis in moderately and extremely myopic eyes 显示文摘 | Magallanes R Shah S Zadok D | 2001 | J Cataract Refract Surg2001，27，7： | 1 |
| 4 | Development of simplified tools to predict blast response of steel beam-column connections 显示文摘 | Morrill K B Crawford J E Magallanes J M | 2007 | Structural Engineering Research Frontiers ASCE2007，249，69： | 1 |
| 5 | The role of adjuvant surgeryin the management of gestational tmphoblastic neoplasia显示文摘 | Cagayan MS Magallanes MS | 2008 | J Reprod Med2008，，7： | 1 |
| 6 | A Randomized Phase 3 Trial Comparing Pemetrexed/Carboplatin and Doeetaxel/Carboplatin as First-Line Treatment for Advanced, Nonsquamous Non-small Cell Lung Cancer显示文摘 | Rodrigues-Pereira J Kim JH Magallanes M | 2011 | J Thorac Oncol2011，6，11： | 1 |
| 7 | A randomized phase 3 trial comparing pemetrexed/carboplatin and docetaxel/ carboplatin as first-line treatment for advanced,nonsquamous nonsmall cell lung cancer显示文摘 | Rodrigues-Pereira J Kim JH Magallanes M | | 0，，11： | 1 |
| 8 | A Randomized Phase 3 Trial Comparing Pemetrexed/Carboplatin and Docetaxel/Carboplatin as First-Line Treatment for Advanced, Nonsquamous Non-small Cell Lung Cancer显示文摘 | José Rodrigues-Pereira Joo-Hang Kim Manuel Magallanes Dae Ho Lee Jie Wang Vinod Ganju Luis Martínez-Barrera Helen Barraclough Maximiliano van Kooten Mauro Orlando | 2011 | Journal of Thoracic Oncology2011，，： | 1 |
| 9 | Genetic basis for natural variation in seed vitamin E levels in Arabidopsis thaliana 显示文摘 | Gilliland LU Magallanes -Lundback M Hemming C | 2006 | Proceedings of the National Academy of Sciences d the United States of America2006，103，18： | 1 |
| 10 | Stability after laser in situ keratomileusis in moderately and extremely myopic eyes 显示文摘 | Magallanes R Shah S Zadok D | 2001 | J Cataract Refract Surg2001，27，7： | 1 |
| 11 | Effect of weeds on insect pests of maize and their natural enemies in southern Mexico 显示文摘 | Penagos DI Magallanes R Valle J | 2003 | International Journal of Pest Management2003，49，2： | 1 |
| 12 | A randomized phase 3 trial comparing pemetrexed/carboplatin a n d d o c e t a x e l/c a r b o p l a t i n a s f i r s t-l i n e t r e a t m e n t f o r advanced,nonsquamous non-small cell lung cancer显示文摘 | Rodrigues-Pereira J Kim JH Magallanes M | 2011 | J Thorac Oncol2011，6，11： | 1 |
| 13 | Stability after laser in situ keratomileusis in moderately and extremly myopia eyes 显示文摘 | Magallanes R Shah S Zadok D Chayet AS Assil KK Montes M | 2001 | J Cataract Refract Surg2001，27，7： | 1 |
| 14 | A ran- domized phase 3 trial comparing pemetrexed/carboplatin and docetaxcl/carboplatin as first-line treatment for ad- vanced,nonsquamous non-small-eell hmg cancer显示文摘 | Rodrigues-Pereira J Kim JH Magallanes M | 2011 | J Thorac Onco12011，6，11： | 1 |
| 15 | Stability after laser in situ keratomileusis in moderately and extermely myopic eyes显示文摘 | Magallanes R Shah S Zadok D | 2001 | J Cataract Refract Surg2001，27，7： | 1 |
| 16 | Genotype-independent transformation of pine显示文摘 | GOULD J H Zhou Y Magallanes M E | 1997 | Cotton and Corn Using Agrobacterium In-Vitro1997，33，3： | 1 |
| 17 | Stability after laser in situ keratomileusis in moderately and extremely myopia eyes显示文摘 | Magallanes R Shah S Zadok D | | 0，，07： | 1 |
| 18 | Waste gypsum-blast furnace slag cement in mortars with granulated slag and silica sand as aggregates显示文摘 | ESCALANTE-GARCIA J I MAGALLANE§RIVERA R X GOROKHOVSKY A | 2009 | Constr Build Mater2009，23，8： | 1 |
| 19 | Stability after laser in situ keratomileusis in moderately and extremely myopic eyes 显示文摘 | Magallanes R Shah S Zadok D Chayet AS Assil KK Montes M | 2001 | J Cataract Refract Surg2001，27，7： | 1 |
| 20 | Laser in situ keratomileusis for simple myopic,mixed,and simple hyperopic astigmatism显示文摘 | ARTURO S MAGALLANES R MONTES M | 1998 | Journal of Refractive Surgery1998，14，2： | 1 |
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