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9篇 您的检索式:作者名="Man Ga"
    题名 作者 年代 出处 被引量
1Clinical and experimental data on bloodless lengthening of lower extremities 显示文摘Ilizarov GA Soibel'man LM 1969Eksp Khir Anesteziol1969,14,4:1
2Breast asymmetry and predisposition to breast cancer显示文摘Scutt D Lancaster GA Manning JT 2006Breast Cancer Res2006,8,2:1
3Further studies on the effects of 5-hydroxytryptophan on plasma glucose and insulin in the mouse 显示文摘man BL Wilson GA 1980Diabetologia1980,19,4:1
4Effect of single oral doses ofsitagliptin,a dipeptidyl Peptidase-4 inhibitor,on incretin and plasmaglucose levels after an oral glucose tolerance test in patients with type 2diatetes显示文摘Herman GA Bei^man A Stevens C 2006J Clin Endocrinol Metab2006,91,11:1
5SpO2/FiO2 vs PaO2/FiO2 : are we ready to establish less invasive indicators for early diagnosis of acute respiratory distress syndrome? 显示文摘Man'aro GA 2010Pediatr Crit Care Med2010,11,1:1
6Risk of early closed reduc- tion in cervical spine subluxation injuries 显示文摘Grant GA Mirza SK Chap man JR 1999J Neurosurg1999,,:1
7Prospective study of aspirin use and risk of stroke in women 显示文摘Iso H Hennekens CH Stampfer MJ R exrode KM Colditz GA Speizer FE Willett WC Man Son JE 1999Stroke1999,30,9:1
8Inhibition of MKK7–JNK by the TOR Signaling Pathway Regulator-Like Protein Contributes to Resistance of HCC Cells to TRAIL-Induced Apoptosis显示文摘In Sung Song Soo Young Jun Hee–Jun Na Hyun–Taek Kim So Young Jung Ga Hee Ha Young–Ho Park Liang Zhe Long Dae–Yeul Yu Jin–Man Kim Joo Heon Kim Jeong–Heon Ko Cheol–Hee Kim Nam–Soon Kim 2012Gastroenterology2012,,5:1
9Spatiotemporally resolved metabolomics and isotope tracing reveal CNS drug targets显示文摘Deconvolution of potential drug targets of the central nervous system(CNS)is particularly challenging because of the complicated structure and function of the brain.Here,a spatiotemporally resolved metabolomics and isotope tracing strategy was proposed and demonstrated to be powerful for deconvoluting and localizing potential targets of CNS drugs by using ambient mass spectrometry imaging.This strategy can map various substances including exogenous drugs,isotopically labeled metabolites,and various types of endogenous metabolites in the brain tissue sections to illustrate their microregional distribution pattern in the brain and locate drug action-related metabolic nodes and pathways.The strategy revealed that the sedative-hypnotic drug candidate YZG-331 was prominently distributed in the pineal gland and entered the thalamus and hypothalamus in relatively small amounts,and can increase glutamate decarboxylase activity to elevateγ-aminobutyric acid(GABA)levels in the hypothalamus,agonize organic cation transporter 3 to release extracellular histamine into peripheral circulation.These findings emphasize the promising capability of spatiotemporally resolved metabolomics and isotope tracing to help elucidate the multiple targets and the mechanisms of action of CNS drugs.Bo Jin Xuechao Pang Qingce Zang Man Ga Jing Xu Zhigang Luo Ruiping Zhang Jiangong Shi Jiuming He Zeper Abliz 2023Acta Pharmaceutica Sinica B2023,13,4:0
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