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您的检索式：作者名="Manan Raval"
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| 1 | Broadband 200-nm second-harmonic generation in silicon in the telecom band显示文摘Silicon is well known for its strong third-order optical nonlinearity,exhibiting efficient supercontinuum and four-wave mixing processes.A strong second-order effect that is naturally inhibited in silicon can also be observed,for example,by electrically breaking the inversion symmetry and quasi-phase matching the pump and the signal.To generate an efficient broadband second-harmonic signal,however,the most promising technique requires matching the group velocities of the pump and the signal.In this work,we utilize dispersion engineering of a silicon waveguide to achieve group velocity matching between the pump and the signal,along with an additional degree of freedom to broaden the second harmonic through the strong third-order nonlinearity.We demonstrate that the strong self-phase modulation and cross-phase modulation in silicon help broaden the second harmonic by 200 nm in the O-band.Furthermore,we show a waveguide design that can be used to generate a second-harmonic signal in the entire nearinfrared region.Our work paves the way for various applications,such as efficient and broadband complementarymetal oxide semiconductor based on-chip frequency synthesizers,entangled photon pair generators,and optical parametric oscillators. | Neetesh Singh Manan Raval Alfonso Ruocco Michael R.Watts | 2020 | Light(Science & Applications)2020，9，1： | 2 |
| 2 | A comprehensive review of the application of nano-silica in oil well cementing显示文摘Oil and Gas Industry is a Multi-Billion Dollar Industry.Drilling a well is costly,right from exploration to drilling and production to Enhanced Oil Recovery(EOR).Nanotechnology has the potential to introduce revolutionary changes in several areas of the oil and gas industry,such as exploration,drilling,cementation,production,EOR,etc.Use of Nanotechnology in the cement slurry can also achieve solutions to some of the problems pertaining to oil well cementation.Nano-silica is a better alternative compared to conventional additives like calcium chloride and silica,because as compared to calcium chloride and silica,the amount of nano-silica to be added is very small.Nano-silica acts as a multi-functional additive.Upon addition of nano-silica to cement slurry,there is a decrease in the thickening time,an increase in the compressive strength,decrease in porosity and permeability within the cement and also a decrease in the fluid loss.Incorporation of nano-silica ensures proper cementation and greater integrity of the well.Nano-silica helps in decreasing the wait on cement(WOC)time and therefore reduces the overall capital cost.Nano-silica is highly recommended for deep offshore wells where high temperature and high pressure are often encountered.This paper discusses the behavior of Nano-silica at high temperatures and also reviews effects of Nano-silica on various properties of cement. | Akshar Thakkar Aakash Raval Shishir Chandra Manan Shah Anirbid Sircar | 2020 | Petroleum2020，6，2： | 2 |
| 3 | Blepharis persica increases testosterone biosynthesis by modulating StAR and 3β-HSD expression in rat testicular tissues显示文摘Objective:To evaluate the effect of methanolic extract and ethyl acetate fraction of methanol extract prepared from the seeds of Blepharis(B.)persica on testosterone biosynthesis and also to elucidate the underlying mechanism.Methods:Forty-eight male Wistar rats were divided into eight groups(n=6 per group).GroupⅠreceived 0.3%w/w gum acacia suspension p.o.and served as the normal control group.GroupⅡwas administered testosterone propionate in arachis oil i.m.as the positive control group.GroupⅢtoⅣreceived B.persica methanolic extract p.o.at doses of 50,100 and 200 mg/kg body weight.GroupⅥtoⅦreceived B.persica ethyl acetate fraction p.o.at doses of 50,100 and 200 mg/kg body weight.The testis was used for biochemical estimation and histological studies.The effects of methanolic extract and ethyl acetate fraction of B.persica on testicular testosterone,mRNA expression corresponding to steroidogenic acute regulatory protein(StAR)and 3β-hydroxysteroid dehydrogenase(3β-HSD)along with 3β-HSD enzyme assay were evaluated in testicular tissues and sperm concentration.Ethyl acetate fraction of B.persica was subjected to column chromatography.Invitro studies were performed using TM3 cell line at three dose levels(50,100,200μg/mL),each for methanolic extract,ethyl acetate fraction and 2-benzoxazolinone for evaluation of their comparative effect on testosterone production.Results:Ethyl acetate fraction and methanolic extract of B.persica could elevate the testicular testosterone content compared to the normal control group.The treatment with methanolic extract and ethyl acetate fraction of B.persica increased the expression of mRNA corresponding to StAR by 6.7 fold and 10.6 fold,respectively,whereas the mRNA expression of 3β-HSD increased by 5.7 fold and 7.3 fold,respectively.Moreover,fraction and extract treatment exhibited increased 3β-HSD activity in the testicular tissues and were found to elevate sperm concentration in seminal fluid.The spermatogenic potential was further ensured by histological observations.2-benzoxazolinone was isolated from ethyl acetate fraction and identified using spectral studies.It showed the ability to increase the testosterone content in the TM3 Leydig cells.Conclusions:Methanolic extract and ethyl acetate fraction of B.persica are able to increase the testicular testosterone in rats by elevating mRNA expression of StAR and 3β-HSD in testicular tissues,leading to increase the sperm concentration. | Nilesh Gaikar Nishit Patel Samir Patel Priyal Patel Piyush Chudasama Manan Raval | 2022 | Asian pacific Journal of Reproduction2022，11，1： | 0 |
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