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72篇 您的检索式:作者名="Mandelkow"
    题名 作者 年代 出处 被引量
1The potential for be-ta-structure in the repeat domain of Tau protein determinesaggregation,synaptic decay, neuronal loss,and coassemblywith endogenous Tau in inducible mouse models of Tauopathy显示文摘Mocanu M Nissen AE Mandelkow EM 2008J Neurosci2008,28,3:1
2Linking amyloid-β and tau: arn- yloid-β induced synaptie dysfunction via local wreckage of the neuronal eytoskeleton显示文摘Zempel H Mandelkow EM 2012Neurodegener Dis2012,10,14:1
3Tau as a marker for Alzheimer's disease显示文摘Mandelkow EM Mandelkow E 1993Trend Bilchem Sci1993,18,:1
4Sequential phosphorylation of Tau by glycogen synthase kinase-3 and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired helical filament-like conformation显示文摘Zheng-Fischhfer Q Biernat J Mandelkow EM 1998Eur J Biochem1998,252,:1
5MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons显示文摘Mandelkow E Thies E Trinczek B 2004J Cell Biol2004,167,1:1
6Missorting of tau in neurons causes degeneration of synapses that can be rescued by the kinase MARK2/Par-1显示文摘Thises E Mandelkow EM 2007J Neurosci2007,27,:1
7The switch of Tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtuble binding region显示文摘Bierna J Mandelkow E M Schroter C 0,,05:1
8Abnormal alzheimerlike phosphorylation of tauprotein by cylin-dependent kinases cdk2and cdk5显示文摘Baumann K Mandelkow E M Biemat J 1993FEBS Lett1993,336,568:1
9The structure of microtubule motor domains 显示文摘Marx A Muller J Mandelkow E 2005Adv Prot Chem2005,71,:1
10Interaction of kinesin motors, microtubules, and MAPs 显示文摘Marx A Muller J Mandelkow E M 2006J Muscle Res Cell Motil2006,27,2:1
11Lost after translation: raissorting of Tau protein and consequencesfor Alzheimer disease 显示文摘Zempel H Mandelkow E 2014Trends Neurosci2014,15,6:1
12Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites显示文摘Curry S Mandelkow H Brick P 1998Nat Struet Biol1998,5,:1
13Missorting of Tau in neurons causes degen-eration of synapses that can be rescued by the kinase MARK2/Par-1显示文摘Thies E Mandelkow EM 2007J Neurosci2007,27,:1
14Oxidation of cysteine - 322 in the repeat domain of mierotubule - associated protein - tau controls the in vitro assembly of paired helical filaments显示文摘Schweers O Mandelkow E Biernat J 1995Proe Natl Acad Sci USA1995,92,18:1
15Phosphorylation of MAP2c and MAP4 by MARK kinases leads to the destabilization of microtubules in cells 显示文摘Ebneth A Drewes G Mandelkow EM 1999Cell Motil Cytoskeleton1999,44,3:1
16Emerging modes of PINK1 signaling: another task for MARK2 显示文摘Matenia D Mandelkow EM 2014Front Mol Neurosci2014,7,:1
17Tau domains,phosphorylation,and interactions with microtubules显示文摘Mandelkow EM Biemat J Drewes G 1995Neurobiol Aging1995,16,3:1
18Microtubule structure 显示文摘Mandelkow E Mandelkow EM 1994 1994Curr Opin Struc Biol1994,4,:1
19Tau in Alzheimer's disease显示文摘Mandelkow EM Mandelkow E 1998Trends Cell Biol1998,8,11:1
20Abnaormal Alzheimer-like phosphorylation of Tau protein by cdk2 and cdk5显示文摘BAUMANN K MANDELKOW E G BIERNAT J 1993FEBS Letters1993,336,:1
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