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| 1 | Aberrant p53 protein expression is associated with an increased risk of neoplastic progression in patients with Barrett’s oesophagus显示文摘 | Florine Kastelein Katharina Biermann Ewout W Steyerberg Joanne Verheij Marit Kalisvaart Leendert H J Looijenga Hans A Stoop Laurens Walter Ernst J Kuipers Manon C W Spaander Marco J Bruno | 2013 | Gut2013，，12： | 2 |
| 2 | The product of the UTH1 gene, required for Baxinduced cell death in yeast, is involved in the response to rapamycin显示文摘 | Camougrand N Grelaud-Coq A Marza E Priault M Bessoule J J Manon S | 2003 | Mol Microbiol2003，47，： | 1 |
| 3 | Quantitative Karyotype analysis in the mussel Mytilus edulis显示文摘 | | 1983 | Aquaculture1983，33，： | 1 |
| 4 | Deformable image registration and replanning in head and neck radiotherapy for optimization of parotid sparing 显示文摘 | Meeks S L Manon R R Kupelian P A | 2006 | Int J Radiat Oncol Biol Phys2006，66，： | 1 |
| 5 | Solution structure of NOD1 CARD and mutational analysis of its interaction with the CARD of downstream kinase RICK 显示文摘 | MANON F FAVIER A NUNEZ G | 2007 | J Mol Biol2007，365，1： | 1 |
| 6 | Interferon beta promotes nerve growth factor secretion early in the course of multiple sclerosis显示文摘 | Katarzyna B Jack P A Manon B | 2005 | Arch Neurol2005，62，： | 1 |
| 7 | Phase II trial of radiosurgery for one to three newly diagnosed brain metastases from renal cell carcinoma, melanoma, and sarcoma: an Eastern Cooperative Oncology Group study (E 6397) 显示文摘 | Manon R O'Neill A Knisely J | 2005 | J Clin Oncol2005，23，34： | 1 |
| 8 | Development of a new orthotopic animal model of metastatic liver cancer in the rabbit VX2 model:effect on metastases after partial hepatectomy,intra-arterial treatment with 3-bromopyruvate and chemoembolization显示文摘 | Josephina A Vossen Manon Buijs Labiq Syed | 2008 | Clin Exp Metastasis2008，25，7： | 1 |
| 9 | Sensitivity and specificity of muhimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers : results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) 显示文摘 | Manon U Gentry-Maharaj A Hallett R | 2009 | Lancet Oncol2009，10，4： | 1 |
| 10 | Phase Ⅱ trial of radiosurgery for one to three newly diagnosed brain metastases from renal cell carcinoma, melanoma, and sarcoma: an Eastern Cooperative Oneology Group Study (E 6397) 显示文摘 | Manon R O'Neill A Knisely J | 2005 | J Clin Oncol2005，23，34： | 1 |
| 11 | Phase Ⅱ trial of radiosurgery for one to three newly diagnosed brain metastases from renal cell carcinoma, melanoma, and sarcoma: An Eastern Cooperative Ontology Group study ( E6397 ) 显示文摘 | Manon R O'Neill A Knisely J | 2005 | J Clin Oncol2005，23，： | 1 |
| 12 | The utility of magnetoencephalography in the presurgical evaluation of refrac- tory insular cpilepsy显示文摘 | Ismail S Mohamed Steve A Gibbs Manon Robert | 2013 | Epilepsia2013，54，11： | 1 |
| 13 | Fine-needle aspiration cytology of castleman disease:Case report with review of the literature显示文摘 | Majorie D Rene'P Roger T Manon A | 2008 | Diagnostic Cytopathology2008，36，： | 1 |
| 14 | Phase Ⅱ trial of radiosurgea-y for one to three newly diagnosed brain metastases from renal cell eaiei-noma, melanoma, and sarcoma: an Eastern Cooperative 0ncology Group study(E 6397) 显示文摘 | Manon R O' Neill A Knlsely J | 2005 | J din 0neol2005，23，34： | 1 |
| 15 | Phase II trial of radiosurgery for one to three newly diagnosed brain metastatases from renal cell carcinoma, melanoma, and sarcoma : an Eastern Coperative Onco- ogy Group study ( E 6397 ) 显示文摘 | Manon R Oneill A Knisely J | 2005 | Clin Oneol2005，23，34： | 1 |
| 16 | Missed colorectal cancers in a fecal immunochemical test-based screening program: Molecular profiling of interval carcinomas显示文摘BACKGROUND For optimizing fecal immunochemical test(FIT)-based screening programs,reducing the rate of missed colorectal cancers(CRCs)by FIT(FIT-interval CRCs)is an important aspect.Knowledge of the molecular make-up of these missed lesions could facilitate more accurate detection of all(precursor)lesions.AIM To compare the molecular make-up of FIT-interval CRCs to lesions that are detected by FIT[screen-detected CRCs(SD-CRCs)].METHODS FIT-interval CRCs observed in a Dutch pilot-program of FIT-based screening were compared to a control group of SD-CRCs in a 1:2 ratio,resulting in 27 FIT-interval CRC and 54 SD-CRCs.Molecular analyses included microsatellite instability(MSI),CpG island methylator phenotype(CIMP),DNA sequence mutations and copy number alterations(CNAs).RESULTS Although no significant differences were reached,FIT-interval CRCs were more often CIMP positive and MSI positive(33%CIMP in FIT-interval CRCs vs 21%in SD-CRCs(P=0.274);19%MSI in FIT-interval CRCs vs 12%in SD-CRCs(P=0.469)),and showed more often serrated pathway associated features such as BRAF(30%vs 12%,P=0.090)and PTEN(15%vs 2.4%,P=0.063)mutations.APC mutations,a classic feature of the adenoma-carcinoma-sequence,were more abundant in SD-CRCs(68%vs 40%in FIT-interval CRCs P=0.035).Regarding CNAs differences between the two groups;FIT-interval CRCs less often showed gains at the regions 8p11.22-q24.3(P=0.009),and more often gains at 20p13-p12.1(P=0.039).CONCLUSION Serrated pathway associated molecular features seem to be more common in FIT-interval CRCs,while classic adenoma carcinoma pathway associated molecular features seem to be more common in SD-CRCs.This indicates that proximal serrated lesions may be overrepresented among FITinterval CRCs. | Manon van der Vlugt Beatriz Carvalho Joelle Fliers Nahid Montazeri Christian Rausch Esmée J Grobbee Manon van Engeland Manon C W Spaander Gerrit A Meijer Evelien Dekker | 2022 | World Journal of Gastrointestinal Oncology2022，14，11： | 0 |
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