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| 1 | Green Functions with Pulsating Sources in A Two-Layer Fluid of Finite Depth显示文摘The derivation of Green function in a two-layer fluid model has been treated in different ways.In a two-layer fluid with the upper layer having a free surface,there exist two modes of waves propagating due to the free surface and the interface.This paper is concerned with the derivation of Green functions in the three dimensional case of a stationary source oscillating.The source point is located either in the upper or lower part of a two-layer fluid of finite depth.The derivation is carried out by the method of singularities.This method has an advantage in that it involves representing the potential as a sum of singularities or multipoles placed within any structures being present.Furthermore,experience shows that the systems of equations resulted from using a singularity method possess excellent convergence characteristics and only a few equations are needed to obtain accurate numerical results.Validation is done by showing that the derived two-layer Green function can be reduced to that of a single layer of finite depth or that the upper Green function coincides with that of the lower,for each case.The effect of the density on the internal waves is demonstrated.Also,it is shown how the surface and internal wave amplitudes are compared for both the wave modes.The fluid in this case is considered to be inviscid and incompressible and the flow is irrotational. | MANYANGA D.O 段文洋 | 2011 | China Ocean Engineering2011，25，4： | 2 |
| 2 | Improved reversed phase liquid chromatographic method with pulsed electrochemical detection for tobramycin in bulk and pharmaceutical formulation显示文摘Tobramycin is one of the aminoglycoside antibiotics that lack a UV absorbing chromophore. However, the application of pulsed electrochemical detection (PED) has been used successfully for the analysis of this and similar antibiotics. This work describes an improved liquid chromatographic (LC) method combined with PED, which is able to separate much more impurities than before. Using a Discovery C-18 RP column (250 mm 4.6 mm i.d., 5 mm), isocratic elution was carried out with a mobile phase, containing sodium sulfate (35 g/L), sodium octanesulphonic acid (1 g/L), tetrahydrofuran (14 mL/L) and 0.2 M phosphate buffer pH 3.0 (50 mL/L). Using these experimental conditions, the limit of quantification (LOQ, S/N 10) was 5 ng. The linearity was examined in the range LOQ-60 mg/mL and the coefficient of determination was 0.998. The method also proved to be repeatable and the recovery was close to 100%. The influence of the different chromatographic parameters on the separation was investigated by means of an experimental design. The proposed method is useful in quality control of tobramycin drug substances and drug products. | Vicky Manyanga Ehab Elkady Jos Hoogmartens Erwin Adams | 2013 | Journal of Pharmaceutical Analysis2013，3，3： | 1 |
| 3 | Improved liquid chromatographic method with pulsed electrochemical detection for the analysis of gentamicin显示文摘 | MANYANGA V KREFT K DIVJAK B | 2008 | J Chromatogr A2008，1189，： | 1 |
| 4 | Comparison of Liquid Chromatographic Methods with Direct Detection for the Analysis of Gentamicin显示文摘 | MANYANGA V GRISHINA O YUN Z | 2007 | J Pharma Biomed Anal2007，45，： | 1 |
| 5 | Comparison of liquid chromatographic methods with direct detection for the analysis of gentamicin显示文摘 | Vicky Manyanga Olga Grishina Erwin Adams | 2007 | Journal of Pharmaceutical and Biomedical Analysis2007，45，： | 1 |
| 6 | Improved liquid chromatographic method with pulsed electrochemical de- tection for the analysis of kanamycin显示文摘 | Manyanga V Dhulipalla R L Hoogmartens J | 2010 | rnal of Chromatog raphy A2010，1217，24： | 1 |
| 7 | High‐performance thin layer chromatography to assess pharmaceutical product quality显示文摘 | Eliangiringa Kaale Vicky Manyanga Narsis Makori David Jenkins Samuel Michael Hope Thomas Layloff | 2014 | Trop Med Int Health2014，，6： | 1 |
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