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1篇 您的检索式:作者名="Manzhan Zhan"
    题名 作者 年代 出处 被引量
1G protein-coupled receptors in neurodegenerative diseases and psychiatric disorders显示文摘Neuropsychiatric disorders are multifactorial disorders with diverse aetiological factors.Identifying treatment targets is challenging because the diseases are resulting from heterogeneous biological,genetic,and environmental factors.Nevertheless,the increasing understanding of G protein-coupled receptor(GPCR)opens a new possibility in drug discovery.Harnessing our knowledge of molecular mechanisms and structural information of GPCRs will be advantageous for developing effective drugs.This review provides an overview of the role of GPCRs in various neurodegenerative and psychiatric diseases.Besides,we highlight the emerging opportunities of novel GPCR targets and address recent progress in GPCR drug development.Thian-Sze Wong Guangzhi Li Shiliang Li Wei Gao Geng Chen Shiyi Gan Manzhan Zhan Honglin Li Song Wu Yang Du 2023Signal Transduction and Targeted Therapy2023,8,6:0
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