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| 1 | A sequential model of bargaining in logic programming显示文摘 | Wu CHEN Dongmo ZHANG Maonian WU | 2015 | Frontiers of Computer Science2015,9,3: | 1 |
| 2 | Phylogenetic patterns suggest frequent multiple origins of secondary metabolites across the seed-plant‘tree of life’显示文摘To evaluate the phylogenetic patterns of the distribution and evolution of plant secondary metabolites(PSMs),we selected 8 classes of PSMs and mapped them onto an updated phylogenetic tree including 437 families of seed plants.A significant phylogenetic signal was detected in 17 of the 18 tested seed-plant clades for at least 1 of the 8 PSM classes using the D statistic.The phylogenetic signal,nevertheless,indicated weak clustering of PSMs compared to a random distribution across all seed plants.The observed signal suggests strong diversifying selection during seed-plant evolution and/or relatively weak evolutionary constraints on the evolution of PSMs.In the survey of the current phylogenetic distributions of PSMs,we found that multiple origins of PSM biosynthesis due to external selective forces for diverse genetic pathways may have played important roles.In contrast,a single origin of PSMs seems rather uncommon.The distribution patterns for PSMs observed in this study may also be useful in the search for natural compounds for medicinal purposes. | Yongzeng Zhang Tao Deng Lu Sun Jacob B.Landis Michael J.Moore Hengchang Wang Yuehua Wang Xiaojiang Hao Jijun Chen Shenghong Li Maonian Xu Pema-Tenzin Puno Peter H.Raven Hang Sun | 2021 | National Science Review2021,8,4: | 1 |
| 3 | Subretinal transplantation of mouse retinal progenitor cells显示文摘The development of cell replacement techniques is promising as a potential treatment for photoreceptor loss. However, the limited integration ability of donor and recipient cells presents a challenge following transplantation. In the present study, retinal progenitor cells (RPCs) were harvested from the neural retinas of enhanced green fluorescent protein mice on postnatal day 1, and expanded in a neurobasal medium supplemented with fetal bovine serum without endothelial growth factor. Using a confocal microscope, immunohistochemistry demonstrated that expanded RPCs in vitro maintain retinal stem cell properties and can be differentiated into photoreceptor cells. Three weeks after transplantation, subretinal transplanted RPCs were found to have migrated and integrated into the outer nuclear layer of recipient retinas with laser injury, some of the integrated cells had differentiated into photoreceptors, and a subpopulation of these cells expressed photoreceptor specific synaptic protein, appearing to form synaptic connections with bipolar cells. These results suggest that subretinal transplantation of RPCs may provide a feasible therapeutic strategy for the loss of retinal photoreceptor cells. | Caihul Jiang Maonian Zhang Henry Klassen Michael Young | 2011 | Neural Regeneration Research2011,6,7: | 1 |
| 4 | A new classification for epidemiological study of me- chanical eye injuries显示文摘ObjectiveConsidering 在在我们的流行病学的学习由伯明翰眼睛损伤术语(BETT ) 与眼睛损伤分类一些案例的困难,我们基于 BETT.MethodsA 回顾的调查为机械眼睛损害的流行病学的学习介绍一个新分类从 2005 年 1 月在 31 所医院里被执行到 2010 年 12 月。有眼睛损害的住院病人的所有医药记录被考察。10 718 个病人(11 227 只眼睛) 的一个总数作为机械眼睛损害被诊断。所有机械眼睛损害被试试用 BETT 被分类。当一些眼睛损害是困难的分类时。我们记录了损害类型和案例数字。一个新分类也为一样的 project.ResultsOf 基于 BETT 被使用有机械眼睛损害的 10 718 个病人(11 227 只眼睛) ,下列盒子不能被 BETT 分类:有仅仅轨道或眼睛的 adnexa 损害的 1 488 个病人( 1 559 只眼睛), 1 961 ( 2 054 )与轨道或眼睛的 adnexa 损害联系的地球损害, 271 ( 284 )眼睛的表面外国身体( OSFB )或眼睛的墙外国身体( OWFB ), 77 ( 89 )殴打, 9 ( 11 )薄片状的撕裂与 OSFB 或 OWFB 联系了,( 30 ) 29 破裂把外国身体与 OSFB , OWFB 或 intraocular 联系了并且 60 ( 62 )撕裂与 OSFB 或 OWFB 联系了。当时根据我们的新分类,没有任何 difficulty.ConclusionDifficulty,所有眼睛损害能在由 BETT 在流行病学的学习分类一些眼睛损害被分类把一些麻烦带到我们的学习,它能被我们的新眼睛损害分类解决到某程度。另外的眼科医师介绍更好的使分类更完美,这被希望。 | Xiao Jianhe Zhang Maonian Li Shiyang Jiang Caihui Jiang Hua Zhang Ying Qiu Huaiyu | 2014 | Chinese Journal of Traumatology2014,17,1: | 1 |
| 5 | Effects of Melatonin on Streptozotocin-Induced Retina Neuronal Apoptosis in High Blood Glucose Rat显示文摘 | Xiaoyan Li Maonian Zhang Weiqiang Tang | 2013 | Neurochemical Research2013,,3: | 1 |
| 6 | Clinical Features and Differential Diagnosis of Acute Idiopathic Blind Spot Enlargement Syndrome显示文摘Purpose:To study the clinical manifestations and the diagnostic and differential diagnostic characteristics of acute idiopathic blind spot enlargement syndrome(AIBSES).Methods:.Six patients diagnosed with AIBSES underwent complete eye examinations including fundus photography,fundus fluorescein angiography(FFA), indocyanine green angiography(ICGA), optical coherence tomography(OCT),electroretinogram(ERG), and visual field examinations.Results: All patients had enlarged blind spots of variable sizes and densities..Three eyes had mild swelling of the optic disc and one eye had peripapillary scarring that corresponded to the permanent field defect. Two patients who underwent FFA had fluorescein leakage of blood vessels around the optic disc and ICGA highlighted diffuse, small hypofluorescent spots scattering throughout the posterior pole..OCT showed that the inner and outer segment(IS / OS).line were absent in five patients and the middle cone outer segment tip line was absent in the nasal macular area in one eye.Conclusion: AIBSES is a rare outer retinopathy. Visual field examination and OCT are the most important means of detection. ICGA and FAF can determine the range of lesions earlier, and the progress of the disease should be taken into account when making a diagnosis. | Xiaocui Liu Bing Chen Maonian Zhang Houbin Huang | 2014 | Eye Science2014,29,3: | 0 |