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| 1 | Data analysis of permanent GPS networks in Italy and surrounding regions:application of a distributed processing approach显示文摘 | Enrico Serpelloni Giuseppe Casula Alessandro Galvani Marco Anzidei Paolo Baldi | 2006 | Annals of Geophysics2006，49，45： | 1 |
| 2 | Finite-Precision Analysis of Demappers and Decoders for LDPC-Coded M-QAM Systems 显示文摘 | Marco Baldi Franco Chiaraluce | 2009 | IEEE Transactions on Broadcasting2009，55，2： | 1 |
| 3 | Effect of ancient Khorasan wheat on gut microbiota,inflammation,and short-chain fatty acid production in patients with fibromyalgia显示文摘BACKGROUND Fibromyalgia(FM)syndrome is mainly characterized by widespread pain,sleeping disorders,fatigue,and cognitive dysfunction.In many cases,gastrointestinal distress is also reported,suggesting the potential pathogenic role of the gut microbiota(GM).The GM is deeply influenced by several environmental factors,especially the diet,and recent findings highlighted significant symptom improvement in FM patients following various nutritional interventions such as vegetarian diet,low-fermentable oligosaccharides,disaccharides,monosaccharides,and polyols based diets,gluten-free diet,and especially an ancient grain supplementation.In particular,a recent study reported that a replacement diet with ancient Khorasan wheat led to an overall improvement in symptom severity of FM patients.AIM To examine the effects of ancient Khorasan wheat on the GM,inflammation,and short-chain fatty acid production in FM patients.METHODS After a 2-wk run-in period,20 FM patients were enrolled in this randomized,double-blind crossover trial.In detail,they were assigned to consume either Khorasan or control wheat products for 8 wk and then,following an 8-wk washout period,crossed.Before and after treatments,GM characterization was performed by 16S rRNA sequencing while the fecal molecular inflammatory response and the short-chain fatty acids(SCFAs)were respectively determined with the Luminex MAGPIX detection system and a mass chromatography-mass spectrometry method.RESULTS The Khorasan wheat replacement diet,in comparison with the control wheat diet,had more positive effects on intestinal microbiota composition and on both the fecal immune and SCFAs profiles such as the significant increase of butyric acid levels(P=0.054),candidatus Saccharibacteria(P=9.95e-06)and Actinobacteria,and the reduction of Enterococcaceae(P=4.97e-04).Moreover,the improvement of various FM symptoms along with the variation of some gut bacteria after the Khorasan wheat diet have been documented;in fact we reported positive correlations between Actinobacteria and both Tiredness Symptoms Scale(P<0.001)and Functional Outcome of Sleep Questionnaire(P<0.05)scores,between Verrucomicrobiae and both Widespread Pain Index(WPI)+Symptom Severity scale(SS)(P<0.05)and WPI(P<0.05)scores,between candidatus Saccharibacteria and SS score(P<0.05),and between Bacteroidales and Sleep-Related and Safety Behaviour Questionnaire score(P<0.05).CONCLUSION The replacement diet based on ancient Khorasan wheat results in beneficial GM compositional and functional modifications that positively correlate with an improvement of FM symptomatology. | Simone Baldi Giuditta Pagliai Monica Dinu Leandro Di Gloria Giulia Nannini Lavinia Curini Marco Pallecchi Edda Russo Elena Niccolai Giovanna Danza Stefano Benedettelli Giovanna Ballerini Barbara Colombini Gianluca Bartolucci Matteo Ramazzotti Francesco Sofi Amedeo Amedei | 2022 | World Journal of Gastroenterology2022，28，18： | 1 |
| 4 | Decomposition of hexamethylcyclotrisiloxane over solid oxides显示文摘 | ELISABETTA Finocchio GILBERTO Garuti MARCO Baldi | 2008 | Chemosphere2008，72，： | 1 |
| 5 | Remove of siloxane with adsorption 显示文摘 | ELISABETTA Finocchio GILBERTO Garuti MARCO Baldi | 2008 | Chemosphere2008，72，： | 1 |
| 6 | Characterization of manganese and iron oxides as combustion catalysts for propane and propene 显示文摘 | Marco Baldi Vicente Sanchez Escribano Jos Amanuel Gallardo Amores | 1998 | Applied Catalysis B: Environmental1998，17，3： | 1 |
| 7 | Reverse-flow catalytic burners: response to periodical variations in the feed 显示文摘 | Marco Cittadini Marco Vanni Antonello A Barresi Giancarlo Baldi | 2001 | Chemical Engineering Science2001，56，： | 1 |
| 8 | Biotransformation of mercury by bacteria isolated from a river collecting cinnabar mine waters显示文摘 | Franco Baldi Marco F Gregory O J | 1989 | Microbial Ecology1989，17，3： | 1 |
| 9 | Ahybrid decoding scheme for short non-binary LDPC codes 显示文摘 | Marco Baldi Franco Chiaraluce Nicola Maturo | 2014 | IEEE Communications Letters2014，18，12： | 1 |
| 10 | Coding with scrambling, concatenation, and HARQ for the AWGN wire-tap channel: A Security Gap Analysis显示文摘 | Marco Baldi | 2012 | IEEE Transactions on Information Forensics and Security2012，7，3： | 1 |
| 11 | The Capacitated Transshipment Location Problem Under Uncertainty: A Computational Study显示文摘 | Mauro Maria Baldi Marco Ghirardi Guido Per- boll Roberto Tadei | 2012 | Proce- dia - Social and Behavioral Sciences2012，39，： | 1 |
| 12 | Effects of viremia and CD4 recovery on gut“microbiome-immunity”axis in treatment-na?ve HIV-1-infected patients undergoing antiretroviral therapy显示文摘BACKGROUND Human immunodeficiency virus type 1(HIV-1)infection is characterized by persistent systemic inflammation and immune activation,even in patients receiving effective antiretroviral therapy(ART).Converging data from many cross-sectional studies suggest that gut microbiota(GM)changes can occur throughout including human immunodeficiency virus(HIV)infection,treated by ART;however,the results are contrasting.For the first time,we compared the fecal microbial composition,serum and fecal microbial metabolites,and serum cytokine profile of treatment-na?ve patients before starting ART and after reaching virological suppression,after 24 wk of ART therapy.In addition,we compared the microbiota composition,microbial metabolites,and cytokine profile of patients with CD4/CD8 ratio<1(immunological non-responders[INRs])and CD4/CD8>1(immunological responders[IRs]),after 24 wk of ART therapy.AIM To compare for the first time the fecal microbial composition,serum and fecal microbial metabolites,and serum cytokine profile of treatment-na?ve patients before starting ART and after reaching virological suppression(HIV RNA<50 copies/m L)after 24 wk of ART.METHODS We enrolled 12 treatment-na?ve HIV-infected patients receiving ART(mainly based on integrase inhibitors).Fecal microbiota composition was assessed through next generation sequencing.In addition,a comprehensive analysis of a blood broad-spectrum cytokine panel was performed through a multiplex approach.At the same time,serum free fatty acid(FFA)and fecal short chain fatty acid levels were obtained through gas chromatography-mass spectrometry.RESULTS We first compared microbiota signatures,FFA levels,and cytokine profile before starting ART and after reaching virological suppression.Modest alterations were observed in microbiota composition,in particular in the viral suppression condition,we detected an increase of Ruminococcus and Succinivibrio and a decrease of Intestinibacter.Moreover,in the same condition,we also observed augmented levels of serum propionic and butyric acids.Contemporarily,a reduction of serum IP-10 and an increase of IL-8 levels were detected in the viral suppression condition.In addition,the same components were compared between IRs and INRs.Concerning the microflora population,we detected a reduction of Faecalibacterium and an increase of Alistipes in INRs.Simultaneously,fecal isobutyric,isovaleric,and 2-methylbutyric acids were also increased in INRs.CONCLUSION Our results provided an additional perspective about the impact of HIV infection,ART,and immune recovery on the'microbiome-immunity axis'at the metabolism level.These factors can act as indicators of the active processes occurring in the gastrointestinal tract.Individuals with HIV-1 infection,before ART and after reaching virological suppression with 24 wk of ART,displayed a microbiota with unchanged overall bacterial diversity;moreover,their systemic inflammatory status seems not to be completely restored.In addition,we confirmed the role of the GM metabolites in immune reconstitution. | Edda Russo Giulia Nannini Gaetana Sterrantino Seble Tekle Kiros Vincenzo Di Pilato Marco Coppi Simone Baldi Elena Niccolai Federica Ricci Matteo Ramazzotti Marco Pallecchi Filippo Lagi Gian Maria Rossolini Alessandro Bartoloni Gianluca Bartolucci Amedeo Amedei | 2022 | World Journal of Gastroenterology2022，28，6： | 0 |
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