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您的检索式：作者名="Marco Capanni"
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| 1 | Hyperhomocysteinemia and hypercoagulability in primary biliary cirrhosis显示文摘瞄准:在有人半胱氨酸(HCY ) 和 haemostatic 系统的各种各样的部件的 PBC 和它的关系估计 hypercoagulability。方法:我们调查了 51 个 PBC 病人(43F/8M;意味着年龄:63+/-13.9 年) 并且 102 个健康题目(86 个 women/16 人;63+/-13 年) ,并且由 PFA-100 由 Sonoclot 分析和血小板功能在全血评估了 haemostatic 过程设备。我们然后测量了 HCY (禁食并且在蛋氨酸装载以后) ,织物因素(TF ) , thrombin-antithrombin 建筑群(梭织) , D 暗淡(D-D ) , thrombomodulin (TM ) , folic,维生素 B6 和 B12 血浆铺平。C677T 5,10-methylenetetrahydrofolate 还原酶(MTHFR ) 多型性被分析。结果:病人的 Sonoclot 率值是显著地(P<0.001 ) 比那些高控制。山峰价值的 Sonoclot 时间和 PFA-100 闭合时间在病人和控制是可比较的。梭织, TF 和 HCY 层次,两个在禁食并且蛋氨酸以后的装载,显著地(P<0.001 ) 在病人更高与比在控制。维生素缺乏在 45/51 病人(88.2%) 被检测。同型结合的 TT677 MTHFR 遗传型的流行比在控制(17.5%)(P<0.05 ) 在病人(31.4%) 是显著地更高的。Sonoclot 率价值与 HCY 层次和 TF 显著地相关。结论:在 PBC, hyper-HCY 与维生素缺少和基因预先安排因素有关。内皮激活的增加的 TF 和 HCY 层次和符号与 hypercoagulability 被联系并且可以在血凝固激活有一个重要角色。 | Maria Rosa Biagini Alessandro Tozzi Rossella Marcucci Rita Paniccia Sandra Fedi Stefano Milani Andrea Galli Elisabetta Ceni Marco Capanni Raffaele Manta Rosanna Abbate Calogero Surrenti | 2006 | World Journal of Gastroenterology2006，12，10： | 6 |
| 2 | RNA-sequencing indicates high hemocyanin expression as a key strategy for cold adaptation in the Antarctic amphipod Eusirus cf.giganteus clade g3显示文摘We here report the de novo transcriptome assembly and functional annotation of Eusirus cf.giganteus clade g3,providing the first database of expressed sequences from this giant Antarctic amphipod.RNA-sequencing,carried out on the whole body of a single juvenile individual likely undergoing molting,revealed the dominant expression of hemocyanins.The mRNAs encoding these oxygen-binding proteins cumulatively accounted for about 40%of the total transcriptional effort,highlighting the key biological importance of high hemocyanin production in this Antarctic amphipod species.We speculate that this observation may mirror a strategy previously described in Antarctic cephalopods,which compensates for the decreased ability to release oxygen to peripheral tissues at sub-zero temperatures by massively increasing total blood hemocyanin content compared with temperate species.These preliminary results will undoubtedly require confirmation through proteomic and biochemical analyses aimed at characterizing the oxygen-binding properties of E.cf.giganteus clade g3 hemocyanins and at investigating whether other Antarctic arthropod species exploit similar adaptations to cope with the challenges posed by the extreme conditions of the polar environment. | SAMUELE GRECO ELISA D’AGOSTINO CHIARA MANFRIN ANASTASIA SERENA GAETANO GAEL FURLANIS FRANCESCA CAPANNI GIANFRANCO SANTOVITO PAOLO EDOMI PIERO GIULIO GIULIANINI MARCO GERDOL | 2021 | BIOCELL2021，45，6： | 0 |
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