维普中文期刊产品整合服务
16篇 您的检索式:作者名="Marcus DR"
    题名 作者 年代 出处 被引量
1Expression of the Helicobacter pylori ureI gene is required for acidic pH activation of cytoplasmic urease显示文摘Scott DR Marcus EA Weeks DL 0,,02:1
2Removal of focal atheromatons lesions byangioscopically guided high-speed rotary atherectomy显示文摘Ahn SS Auth D Marcus DR 1988J Vasc Surg1988,7,2:1
3Effects of one-year high-in-tensity versus low intensity resistance training program onbone mineral density in older women显示文摘Pruitt LA Taaffe DR Marcus R 1995Journal of bone andmineral research1995,10,11:1
4Expression of the Helicobacter pylori ureI gene is required for acidic pH activation of cytoplasmic urease显示文摘Scott DR Marcus EA Weeks DL 2000Infect Immun2000,68,2:1
5Expression of the Helicobacter pylori ureI gene is required for acidic pH activation of cytoplasmic urease 显示文摘Scott DR Marcus EA Weeks DL 2000Infect Immun2000,68,2:1
6The pGEM and pGEM-T easy vector systems显示文摘Marcus L Hartnett J Storts DR 1996Promega Notes1996,58,:1
7Effects of a one year high intensity versus low intensity resistance training program on bone mineral density in older women显示文摘PRUITT LA TAAFE DR MARCUS R 1995J Bone Miner Res1995,10,:1
8Dynamic muscle strength alterationsto detraining and retraining in elderly men显示文摘Taaffe DR Marcus R 1997Clin Physiol1997,17,3:1
9Post-carotid endarterecto- my hypertension:association with elevated cranial norepi- nephrine显示文摘Ahn SS Marcus DR Moore WS 1989J Vasc Surg1989,9,2:1
10Expression of the Helicobacter pylori ureI gene is required for acidic pH activation of cytoplasmic urease显示文摘Scott DR Marcus EA Weeks DL 2000Infect Immun2000,68,2:1
11Gene expression in vivo shows that Helicobacter pylori colonizes an acidic niche on the gastric surface显示文摘Scott DR Marcus EA Wen Y 2007Proc Natl Acad Sci2007,104,17:1
12Oligomeric and fibrillar species of β-amyloid(Aβ42) both impair mitochondrial function in P301L tau transgenic mice显示文摘We recently provided evidence for a mitochondrial dysfunction in P301L tau transgenic mice,a strain modeling the tau pathology of Alzheimer's disease(AD)and frontotemporal dementia(FTD).In addition to tau aggregates,the AD brain is further characterized by Aβpeptide-containing plaques.When we addressed the role of Aβ,this indicated a synergistic action of tau and Aβpathology on the mitochondria.In the present study,we compared the toxicity of different Aβ42 conformations in light of recent studies suggesting that oligomeric rather than fibrillar Aβmight be the actual toxic species.Interestingly,both oligomeric and fibrillar,but not disaggregated(mainly monomeric)Aβ42 caused a decreased mitochondrial membrane potential in cortical brain cells obtained from FTD P301L tau transgenic mice.This was not observed with cerebellar preparations indicating selective vulnerability of cortical neurons.Furthermore,we found reductions in state 3 respiration,the respiratory control ratio,and uncoupled respiration when incubating P301L tau mitochondria either with oligomeric or fibrillar preparations of Aβ42.Finally,we found that aging specifically increased the sensitivity of mitochondria to oligomeric Aβ42 damage indicating that oligomeric and fibrillar Aβ42 are both toxic,but exert different degrees of toxicity.Anne Eckert Susanne Hauptmann Isabel Scherping Jessica Meinhardt Virginie Rhein Stefan Drse Ulrich Brandt Marcus Fndrich Walter E.Müller Jiirgen Gtz 2016世界最新医学信息文摘2016,16,2:1
13The binding selectivity of vonoprazan (TAK- 438) to the gastric H+ ,K+- ATPase显示文摘SCOTt DR MUNSON KB MARCUS EA 2015Aliment Pharmacol Ther2015,42,1112:1
14The binding selectivity of vonoprazan(TAK-438) to the gastric H*, K+- ATPase 显示文摘Scott DR Munson KB Marcus EA 2015Aliment Pharmaeol Ther2015,42,:1
15Expression of the Helicobacter pylori UreI gene is required for acidic pH activation of cytoplasmic urease显示文摘Scott DR Marcus EA Weeks DL 2000Infect Immun2000,68,:1
16Expression of the Helicobacter pylori ureI gene is required for acidic pH activation of cytoplasmic urease显示文摘Scott DR Marcus EA Weeks DL 2000Infect Immun2000,68,2:1
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费