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| 1 | 应对全球气候变化:全科医生的临床经验和方法显示文摘背景气候变化是全球公共卫生问题,需要全面深入的思考才能获得行之有效的解决方法。本文从理论上阐述全科医生临床经验和方法对于解决气候变化问题的借鉴意义。讨论我们认为全科医生的经验和特殊思考方式对解决气候变化问题是一笔宝贵的财富。这些财富包括,毕生对'首先不造成伤害'和'处理不确定性'的认知、反思和践行,'面对不完整信息时做出必要决策'的能力,对'复杂自适应系统'的认识,对稳态的维持,对意外后果的警醒,对'跨学科和跨专业'重要性的认识。总结全科医生一直以来都是公共卫生的拥护者。他们对复杂人类问题的处理方式也可用于应对气候变化。 | Grant Blashki Alan Abelsohn Robert Woollard Neil Arya Margot W Parkes Paul Kendal Erica Bell R Warren Bell 邵钧 | 2013 | 中国全科医学2013，16，10： | 2 |
| 2 | Infectious, atopic and inflammatory diseases, childhood adversities and familial aggregation are independently associated with the risk for mental disorders: Results from a large Swiss epidemiological study显示文摘AIM To examine the associations between mental disorders and infectious, atopic, inflammatory diseases while adjusting for other risk factors.METHODS We used data from PsyC oL aus, a large Swiss Population Cohort Study(n = 3720; age range 35-66). Lifetime diagnoses of mental disorders were grouped into the following categories: Neurodevelopmental, anxiety(early and late onset), mood and substance disorders. They were regressed on infectious, atopic and other inflammatory diseases adjusting for sex, educational level, familial aggregation, childhood adversities and traumatic experiences in childhood. A multivariate logistic regression was applied to each group of disorders. In a complementary analysis interactions with sex were introduced via nested effects. RESULTS Associations with infectious, atopic and other chronic inflammatory diseases were observable together with consistent effects of childhood adversities and familial aggregation, and less consistent effects of trauma in each group of mental disorders. Streptococcal infections were associated with neurodevelopmental disorders(men), and measles/mumps/rubella-infections with early and late anxiety disorders(women). Gastric inflammatory diseases took effect in mood disorders(both sexes) and in early disorders(men). Similarly, irritable bowel syndrome was prominent in a sex-specific way in mood disorders in women, and, moreover, was associated with early and late anxiety disorders. Atopic diseases were associated with late anxiety disorders. Acne(associations with mood disorders in men) and psoriasis(associations with early anxiety disorders in men and mood disorders in women) contributed sex-specific results. Urinary tract infections were associated with mood disorders and, in addition, in a sex-specific way with late anxiety disorders(men), and neurodevelopmental and early anxiety disorders(women).CONCLUSION Infectious, atopic and inflammatory diseases areimportant risk factors for all groups of mental disorders. The sexual dimorphism of the associations is pronounced. | Vladeta Ajdacic-Gross Aleksandra Aleksandrowicz Stephanie Rodgers Margot Mutsch Anja Tesic Mario Müller Wolfram Kawohl Wulf R?ssler Erich Seifritz Enrique Castelao Marie-Pierre F Strippoli Caroline Vandeleur Roland von K?nel Rosa Paolicelli Markus A Landolt Cornelia Witthauer Roselind Lieb Martin Preisig | 2016 | World Journal of Psychiatry2016，6，4： | 2 |
| 3 | Inhibition of Rho kina- ses increases directional motility of microvascular endotheli- al cells 显示文摘 | Johannes B Jana S Margot R | 2012 | Biochemical Pharmacology2012，83，5： | 1 |
| 4 | The dynamics of autism spectrum disorders: how neurotoxic compounds and neurotransmitters interact显示文摘 | Ilona Q Madeleine R B Margot Van de B | 2013 | Environ Res Public Health2013，10，8： | 1 |
| 5 | Induction of connective tissue growth factor by angiotensin Ⅱ: integration of signaling pathways 显示文摘 | Dominika I Margot R Markus P | 2003 | Arterioscler Thromb Vasc Biol2003，23，： | 1 |
| 6 | Potential of flow pre-whirl at the compressor inlet of automotive engine turbochargers to enlarge surge margin and overcome packaging limitations显示文摘 | Galindo J Serrano J R Margot X | 2007 | International Journal of Heat and Fluid Flow2007，28，3： | 1 |
| 7 | The HIV-1 RT mutant Q151L shows decreased replication capacity, selective highlevel resistance to GS-9148 and hypersusceptibility to tenofovir and zidovudine显示文摘 | Kulkarni R Margot NA Myrick F | 2009 | Antivir Ther2009，141，： | 1 |
| 8 | Potential of flow pre- whirl at the compressor inlet of automotive engine turbochargers to enlarge surge margin and overcome packaging limitations 显示文摘 | Galindo J Serrano J R Margot X | 2007 | International Journal of Heat and Fluid Flow2007，28，： | 1 |
| 9 | serum sotal and free prostate-specific antigen for breast cancer diagnosis in women 显示文摘 | margot H Black M G R iccardo P | 2000 | Clinical Cancer Eesearch2000，6，： | 1 |
| 10 | Topogra- phy of the lunar poles from radar interferometry: A survey of cold trap locations 显示文摘 | Margot J L Campbell D B Jurgens R F | 1999 | Science1999，284，5420： | 1 |
| 11 | Potential of flow pre-whirl at the compressor inlet of automotive engine turbochargers to enlarge surge margin and overcome packaging limitations显示文摘 | Galindo J Serrano 3 R Margot X | 2007 | International Journal of Heat and Fluid Flow2007，28，3： | 1 |
| 12 | Induction of connective tissue growth factor by angiotensin Ⅱ:integration of signaling pathways显示文摘 | DOMINIKA I MARGOT R MARKUS P | 2003 | Arterioscler Thromb Vasc Biol2003，23，： | 1 |
| 13 | Treatment of locked posterior fracture-dislocations of the shoulder by total shoulder arthroplasty显示文摘 | Stephen L Cheng Margot B Mackay Robin R Richards | 1997 | Journal of Shoulder and Elbow Surgery1997，，1： | 1 |
| 14 | 用动态力学热分析方法对单根纤维的测定显示文摘引言由于单根纤维之间的相互磨擦作用,使得对一束纤维(例如纱线或织物)的力学性质的测定结果的意义不很明确。因此,测量单根纤维就成了一个重要的课题。利用配有拉伸夹头的动态力学热分析仪(DMTA。 | R·E·WETTON MARGOT R·MORTON J·C·RICHMOND J·ROSE | 1991 | 国外科学仪器1991，，2： | 1 |
| 15 | Bi20 (fBTA05), a novel trifunctional bispecific antibody (anti- CD20 x anti-CD3 ), mediates efficient killing of B-cell lymphoma cells even with very low CD20 expression lev- els显示文摘 | MICHAEL S MARGOT F PETER R | 2008 | International Journal of Cancer2008，123，5： | 1 |
| 16 | Pharmacokinetics of Gatifloxacin and interaction with an antacid containing aluminum and magnesium显示文摘 | Silne L Susanne Z Margot R | 1999 | Antimicrob Agents Chemother1999，43，5： | 1 |
| 17 | Promoter sequences of a potato pathogenesis-related gene mediate transcriptional activation selectively upon fungal infection显示文摘 | Norbert Martini Margot Egen Irmgard Rüntz Günter Strittmatter | 1993 | MGG Molecular & General Genetics (-)1993，，2： | 1 |
| 18 | Induction of connective tissue growth factor by angiotensin Ⅱ:Integration of signaling pathways显示文摘 | Dominika I Margot R Markus P | 2003 | Arterioscler Thromb Vasc Biol2003，23，10： | 1 |
| 19 | Pharmacokinetics of gatifloxacin and interaction with an antacid containing Aluminum and Magnesium显示文摘 | Silke L Susanne Z Margot R | 1999 | Antimicrob Agents chemother1999，43，5： | 1 |
| 20 | Promoter sequences of a potato pathogenesis-related gene mediate transcriptional activation selectively upon fungal infection显示文摘 | Norbert Martini Margot Egen Irmgard Rüntz Günter Strittmatter | 1993 | MGG Molecular & General Genetics (-)1993，，2： | 1 |
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