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13篇 您的检索式:作者名="Margotti"
    题名 作者 年代 出处 被引量
1In vitro effect of thymosin-alphal and imerferon-alpha on Thl and Th2 cytokine synthesis in patients with eAg-negative chronic hepatitis B显示文摘Loggi E Oramenzi A Margotti M 2008J Viral Hepat2008,15,6:1
2TrKB signalling controls LTP but not LTD expression in the developing rat visual corex 显示文摘 Margotti E Cattaneo A 2000EurJ Neurosci2000,12,:1
3Laboratory sig- ns of acute or recent cytomegalovirus infection are com- mon in cirrhosis of the liver显示文摘Varani S Lazzarotto T Margotti M 2000Journal of Medical Irolo- gy2000,62,1:1
4Ketoprofen,peginterferon 2a and ribavirin for genotype 1 chronic hepatitis C:A phaseⅡ study显示文摘AIM:To evaluate the safety of adding ketoprofen to pegylated-interferon(PEG-IFN)with or without ribavirin and the effect on viral kinetics,STAT1 activity and expression of 2'-5'-oligoadenylate synthetase (2'-5'OAS)in genotype 1 chronic hepatitis C in a phaseⅡstudy. METHODS:Forty-five patients were studied:fifteen were randomized to PEG-IFN plus ribavirin(PR),16 to PEGIFN plus ketoprofen and 14 to PR and ketoprofen.Themolecular study of IFN-dependent signal transduction was conducted in 9 patients from each group. RESULTS:The combination of ketoprofen and PEG- IFN with or without ribavirin was safe and well tolerated.An early activation of STAT1 was observed in ke-toprofen-treated patients,but this activation was less sustained over time.Conversely,ketoprofen plus PEG- IFN and ribavirin induced an early and sustained increase of 2'-5'OAS transcription starting 24 h after the first dose until the 36th wk.These data are consistent with the clinical results,showing a better sustained virological response and a lower relapse rate in patients receiving ketoprofen plus PEG-IFN and ribavirin. CONCLUSION:The addition of ketoprofen to the standard therapy of chronic hepatitis C should be explored in larger randomized clinical studies.Annagiulia Gramenzi Carmela Cursaro Marzia Margotti Clara Balsano Alessandra Spaziani Simona Anticoli Elisabetta Loggi Maddalena Salerno Silvia Galli Giuliano Furlini Mauro Bernardi Pietro Andreone 2009World Journal of Gastroenterology2009,15,47:1
5In vitro effect of thy- mosin-alphal and interferon-alpha on Thl and Th2 cytokine synthesis in patients with e Ag-negative chronic hepatitis B 显示文摘Loggi E Gramenzi A Margotti M 2008J Viral Hepat2008,15,6:1
6In vitro effect of thymosinal phal and interferon alpha on Th1 and Th2 cytokine synthesis in patients with eAg negative chronic hepatitis B显示文摘Loygi E Cramenzi A Margotti M er al 2008J Viral Hrpat2008,15,6:1
7In vitro effect of thymosin - alphal and interferon - alpha on Thl and Th2 cytokine synthesis in patients with eAg - negative chronic hepatitis B 显示文摘Loggi E Gramenzi A Margotti M 2008J Viral Hepat2008,15,6:1
8Letter: calcineurin inhibitor level reduction during treatment with sofosbuvir in liver transplanted patients显示文摘R. Vukotic M. C. Morelli A.D. Pinna M. Margotti F.G. Foschi E. Loggi M. Bernardi P. Andreone 2014Aliment Pharmacol Ther2014,,4:1
9In vitro effect of thymosin-alpha 1 and interferon-alpha on Thl and Th2 cytokine synthesis in patients with eAg-negative chronic hepatitis B 显示文摘Loggi E Gramenzi A Margotti M 2008J Viral Hepat2008,15,:1
10In vitro effect of thymosin-alphal and interferon-alpha on Thl and Th2 cytokine synthesis in patients with eAg-negative chronic hepatitis B显示文摘Loggi E Gramenzi A Margotti M 2008J Viral Hepat2008,15,:1
11Functional blockade of tyrosine kinase A in the rat basal forebrain by a novel antagonistic anti-receptor monoclonal antibody显示文摘Cattaneo A Capsoni S Margotti E 1999J Neurosci1999,19,22:1
12TAB signaling controls LTP butnot LTD expression in the developing rat visual cortex显示文摘Sermasi E Margotti E Cattaneo A 2000EurJNcurosci2000,12,4:1
13Genetic variability of hepatitis C virus in HBV/HCV co-infection and HCV single-infection显示文摘M. S. De Mitri G. Morsica R. Cassini S. Bagaglio P. Andreone G. Bianchi M. Margotti M. Bernardi 2005Archives of Virology2005,,2:1
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