|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Malignancies after renal transplantation during 33 years at a single center显示文摘 | Gyula Végs? Maria Tóth Márta Hídvégi éva Toronyi Robert Mlanger Elek Dinya András Tóth Ferenc Perner Jen? Járay | 2007 | Pathology & Oncology Research2007，，1： | 1 |
| 2 | Effect of the micro-environment on α-synuclein conversion and implication in seeded conversion assays显示文摘Background: α-Synuclein is a small soluble protein,whose physiological function in the healthy brain is poorly understood.Intracellular inclusions of α-synuclein,referred to as Lewy bodies(LBs),are pathological hallmarks ofαsynucleinopathies,such as Parkinson’s disease(PD)or dementia with Lewy bodies(DLB).Main body:Understanding of the molecular basis as well as the factors or conditions promoting α-synuclein misfolding and aggregation is an important step towards the comprehension of pathological mechanism ofαsynucleinopathies and for the development of efficient therapeutic strategies.Based on the conversion and aggregation mechanism of α-synuclein,novel diagnostic tests,such as protein misfolding seeded conversion assays,e.g.the real-time quaking-induced conversion(RT-QuIC),had been developed.In diagnostics, α-synuclein RT-QuIC exhibits a specificity between 82 and 100%while the sensitivity varies between 70 and 100%among different laboratories.In addition,the α-synuclein RT-QuIC can be used to study the α-synuclein-seeding-characteristics of different α-synucleinopathies and to differentiate between DLB and PD.Conclusion:The variable diagnostic accuracy of current α-synuclein RT-QuIC occurs due to different protocols,cohorts and material etc..An impact of micro-environmental factors on the α-synuclein aggregation and conversion process and the occurrence and detection of differential misfolded α-synuclein types or strains might underpin the clinical heterogeneity of α-synucleinopathies. | Niccolo Candelise Matthias Schmitz Katrin Thüne Maria Cramm Alberto Rabano Saima Zafar Erik Stoops Hugo Vanderstichele Anna Villar-Pique Franc Llorens Inga Zerr | 2020 | Translational Neurodegeneration2020，9，1： | 1 |
| 3 | The Effects of Attitdes and Personality Traits on Mode Choice 显示文摘 | Vredin J Maria TH and Johansson P | 2006 | Transporta- tion Research Part A: Policy and Practice2006，40，6： | 1 |
| 4 | Ankle-brachial index as a predictor of the extent of coronary atherosclerosis and cardiovascular events in patients with coronary artery disease显示文摘 | Christos M Papamichael John P Lekakis Kimon S Stamatelopoulos Theodoros G Papaioannou Maria K Alevizaki Adriana T Cimponeriu John E Kanakakis Aggeliki Papapanagiotou Anastasios Th Kalofoutis Stamatios F Stamatelopoulos | 2000 | The American Journal of Cardiology2000，，6： | 1 |
| 5 | Shelf life modelling of frozen shrimp at variable temperature conditions显示文摘 | Th~ofania Tsironi Efimia Dermesonlouoglou Maria Giannakourou ct al | 2009 | LWT- Food Science and Technology2009，42，2： | 1 |
| 6 | Pilot Plant Investigation of the Leaching Process for the Recovery of Scandium from Red Mud 显示文摘 | Hatzilyberis Th | 2002 | Industrial and Engineering Chemistry Research2002，41，23： | 1 |
| 7 | Pilot-Plant Investigation of the Leaching Process for the Recovery of Scandium from Red Mud显示文摘 | Ochsenkuhn-Petropoulou Maria Hatzilyberis Th | 2002 | Industrial and Engineering Chemistry Research2002，41，23： | 1 |
| 8 | Randomised comparison of primary stent placement versus primary angioplasty followed by selective stent placement in patients with iliac-artery occlusive disease显示文摘 | Eric Tetteroo Yolanda van der Graaf Johanna L Bosch Andries D van Engelen Maria GM Hunink Bert C Eikelboom Willem P Th M Mali | 1998 | The Lancet . 1998 (9110)1998，，： | 1 |
| 9 | Malignancies after renal transplantation during 33 years at a single center显示文摘 | Gyula Végs? Maria Tóth Márta Hídvégi éva Toronyi Robert Mlanger Elek Dinya András Tóth Ferenc Perner Jen? Járay | 2007 | Pathology & Oncology Research2007，，1： | 1 |
| 10 | An educational intervention to improve physician reporting of adverse drug reactions a cluster-randomized controlled trial 显示文摘 | ADOLFO F MARIA TH JORGE P | 2006 | JAMA2006，296，9： | 1 |
| 11 | Pi-lot-plant investigation of the leaching process for the recovery of scandium from red mud显示文摘 | Maria Th O Konstantinos S H Leonidas N M | 2002 | Ind Eng Chem Res2002，41，23： | 1 |
| 12 | Intensity modulated ra-diation therapy versus three dimensional conformal radiation thera-py for treatment of high grade glioma : A radiobiological modelingstudy显示文摘 | De La TH Salahuddin A Maria TK | 2010 | J X-ray Sci Technol2010，18，4： | 1 |
| 13 | Cloning of Trypanosoma brucei and Leishmania major genes encoding the glcnac-phosphatidylinositol de-n-acetylase of glycosylphosphatidylinositol biosynthesis that is essential to the african sleeping sickness parasite 显示文摘 | Chang TH Kenneth GM Maria LS | 2002 | J Biol Chem2002，277，： | 1 |
| 14 | Brain activation to favorite music in healthy controls and depressed patients显示文摘 | Elizabeth A. Osuch Robyn L. Bluhm Peter C. Williamson Jean Théberge Maria Densmore Richard W.J. Neufeld | 2009 | NeuroReport2009，，13： | 1 |
| 15 | Addition of respiratory exercises to conventional rehabilitation for children and adolescents with cerebral palsy:a systematic review and meta-analysis显示文摘Background Respiratory dysfunctions are an important cause of morbidity and death in cerebral palsy(CP)populations.Respiratory exercises in addition to conventional rehabilitation have been suggested to improve respiratory status in CP patients.The objective of this systematic review and meta-analysis was to verify the effects of the addition of respiratory exercises to conventional rehabilitation on pulmonary function,functional capacity,respiratory muscle strength,gross motor function and quality of life in children and adolescents with CP.Methods We searched for randomized controlled clinical trials in PubMed/Medline,Lilacs,SciELO,EMBASE and Physi-otheraphy Evidence(PEDro)from their inception until July 2022 without language restrictions.Studies that included respiratory exercises(breathing exercise program;feedback respiratory training;incentive spirometer exercise;inspiratory muscle training;and combination of respiratory exercises+incentive spirometer exercise)in combination with conventional rehabilitation for children and adolescents with CP were evaluated by two independent reviewers.The mean difference(MD)and 95%confidence interval(CI)were estimated by random effect models.Results Ten studies met the eligibility criteria,including 324 children aged from 6 to 16 years.The meta-analysis showed an improvement in inspiratory muscle strength of 22.96 cmH2O(18.63-27.27,n=55)and pulmonary function of 0.60(0.38-0.82,n=98)for forced vital capacity(L);0.22(0.06-0.39,n=98)for forced expiratory volume at 1 second(L);and 0.50(0.05-0.04,n=98)for peak expiratory flow(L/min).Functional skills in daily living activities improved in the intervention group.Caregivers'assistance of daily living activities,functional capacity,gross motor function and expiratory muscle strength showed a nonsignificant improvement.Social well-being and acceptance and functioning domains improved in only one study.Conclusions Emerging data show significant enhancements in inspiratory muscle strength and pulmonary function in CP patients after respiratory training in addition to conventional rehabilitation.There is no consensus on the frequency,type or intensity of respiratory exercises for children with and adolescents with CP. | Thálita Raysa de Lima Crispim Mansueto Gomes Neto Tafnes Rayane Lima Crispim Renivaldo Batista Dias Maria Déborah Monteiro de Albuquerque Micheli Bernardone Saquetto Paulo André Freire Magalhães | 2023 | World Journal of Pediatrics2023，19，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员