|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Evidence based medicine and surgical approaches for colon cancer: Evidences, benefits and limitations of the laparoscopic vs open resection显示文摘AIM:To report a meta-analysis of the studies that compared the laparoscopic with the open approach for colon cancer resection.METHODS:Forty-seven manuscripts were reviewed,33 of which employed for meta-analysis according to the PRISMA guidelines.The results were differentiated according to the study design(prospective randomized trials vs case-control series)and according to the tu-mor’s location.Outcome measures included:(1)shortterm results(operating times,blood losses,bowel function recovery,post-operative pain,return to the oral intake,complications and hospital stay);(2)oncological adequateness(number of nodes harvested in the surgical specimens);and(3)long-term results(including the survivals’rates and incidence of incisional hernias)and(4)costs.RESULTS:Meta-analysis of trials provided evidences in support of the laparoscopic procedures for a several short-term outcomes including:a lower blood loss,an earlier recovery of the bowel function,an earlier return to the oral intake,a shorter hospital stay and a lower morbidity rate.Opposite the operating time has been confirmed shorter in open surgery.The same trend has been reported investigating case-control series and cancer by sites,even though there are some concerns regarding the power of the studies in this latter field due to the small number of trials and the small sample of patients enrolled.The two approaches were comparable regarding the mean number of nodes harvested and long-term results,even though these variables were documented reviewing the literature but were not computable for meta-analysis.The analysis of the costs documented lower costs for the open surgery,however just few studies investigated the incidence of postoperative hernias.CONCLUSION:Laparoscopy is superior for the majority of short-term results.Future studies should better differentiate these approaches on the basis of tumors’location and the post-operative hernias. | Laura Lorenzon Marco La Torre Vincenzo Ziparo Francesco Montebelli Paolo Mercantini Genoveffa Balducci Mario Ferri | 2014 | World Journal of Gastroenterology2014，20，13： | 8 |
| 2 | Survival after radiotherapy in gastric cancer: Systematic review and meta-analysis显示文摘 | Vincenzo Valentini Francesco Cellini Bruce D. Minsky Gian Carlo Mattiucci Mario Balducci Giuseppe D’Agostino Elisa D’Angelo Nicola Dinapoli Nicola Nicolotti Chiara Valentini Giuseppe La Torre | 2009 | Radiotherapy and Oncology2009，，2： | 4 |
| 3 | Hypofractionated and Low Dose Radiotherapy Combined with Temozolomide in Naive Unresectable Glioblastoma:A Pilot Study显示文摘Background/Aim: To assess safety of hypo-fractionated radiotherapy( HyRT) followed by low dose radiation therapy( LD-FRT) plus Temozolomide( TMZ) in naive unresectable Glioblastoma. Methods: Patients( ECOG < 2,age > 18) undergone to biopsy or with gross residual tumor after surgery were enrolled. HyRT( 30 Gy in ten fraction) plus TMZ was administered. From the second adjuvant cycle of TMZ,patients received LD-FRT( 0. 40 Gy twice daily over 5 days,every 28 days) for two cycles. The primary endpoints were safety and toxicity. Moreover we analyzed response,overall survival( OS) and progression-free survival( PFS). Results: Twenty patients were enrolled. Median dose of LD-FRT was 12 Gy. All toxicities were reversible. Four out of 20 patients had Partial Response( PR)and 6 experienced a stable disease( SD). Median OS and PFS were 14 and 11 months,respectively.Conclusions: HyRT followed by LD-FRT plus TMZ is safe and shows good clinical outcomes. A new study is ongoing. | Silvia Chiesa Milena Ferro Stefano Luzi Barbara Diletto Francesco Beghella Bartoli Nicola Dinapoli Gian Carlo Mattiucci Vincenzo Frascino Francesco Miccichè Cesare Colosimo Carmelo Anile Alessandro Olivi Vincenzo Valentini Mario Balducci | 2017 | 肿瘤预防与治疗2017，30，1： | 2 |
| 4 | Multiple giant diverticula of the foregut causing upper gastrointestinal obstruction显示文摘Small bowel diverticulosis represents an uncommon disorder (except for Meckel diverticulum) often misdiagnosed since it causes non-specific gastroin- testinal symptoms. Most of times the diagnosis is carried out in case of related complications, such as diverticulitis, hemorrhage, perforation or obstruction. Intestinal obstruction can be caused by inflammatory stenosis due to repeated episodes of diverticulitis, volvulus, intussusception or jejunal stones. Herein we report a case of multiple jejunal diverticula causing chronic gastrointestinal obstruction. | Genoveffa Balducci Mario Dente Giulia Cosenza Paolo Mercantini Pier Federico Salvi | 2008 | World Journal of Gastroenterology2008，14，20： | 1 |
| 5 | Is a long-term aerobic plusresistance training program feasible for and effective on metabolic pro-files in type 2 diabetic patients显示文摘 | Balducci S Leonetti F Di Mario U | 2004 | Diabetes Care2004，27，3： | 1 |
| 6 | Pulmonary administration of functionalized nanoparticles significantly reduces beta-amyloid in the brain of an Alzheimer's disease murine model显示文摘 | Giulio Sancini Roberta Dal Magro Francesca Ornaghi Claudia Balducci Gianluigi Forloni Marco Gobbi Mario Salmona Francesca Re | 2016 | Nano Research2016，9，7： | 1 |
| 7 | The relationship of pathologic tumor regression grade (TRG) and outcomes after preoperative therapy in rectal cancer显示文摘 | Fabio Maria Vecchio Vincenzo Valentini Bruce D. Minsky Gilbert D.A. Padula Ennapadam S. Venkatraman Mario Balducci Francesco Miccichè Riccardo Ricci Alessio Giuseppe Morganti Maria Antonietta Gambacorta Francesca Maurizi Claudio Coco | 2005 | International Journal of Radiation Oncology Biology Physics2005，，3： | 1 |
| 8 | Is a long-term aerobic plus resistance training program feasible for and effective on metabolic profiles in type 2 diabetic patients显示文摘 | Balducci S F Leonetti U D Mario | 2004 | Diabetes Care2004，27，3： | 1 |
| 9 | Is a long term aerobic plus resistance training program feasible for and effective on meta- bolic profiles in type 2 diabetic patients 显示文摘 | Balducci S Leonetti F Di Mario U | 2004 | Diabetes Care2004，27，3： | 1 |
| 10 | The relationship of pathologic tumor regression grade (TRG) and outcomes after preoperative therapy in rectal cancer显示文摘 | Fabio Maria Vecchio Vincenzo Valentini Bruce D. Minsky Gilbert D.A. Padula Ennapadam S. Venkatraman Mario Balducci Francesco Miccichè Riccardo Ricci Alessio Giuseppe Morganti Maria Antonietta Gambacorta Francesca Maurizi Claudio Coco | 2005 | International Journal of Radiation Oncology, Biology, Physics2005，，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员