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| 1 | 冠状动脉内影像学临床应用专家共识(第一部分):对冠状动脉介入治疗的指导与优化显示文摘欧洲心血管介入协会(EAPCI)专家组系统总结了血管内超声(IVUS)和光学相干断层成像(OCT)这两种血管内影像学检查临床应用指征的现有证据,提供了关于IVUS和OCT指导经皮冠状动脉介入治疗(PCI)的应用价值,并明确了最可能从腔内影像学指导的介入治疗中获得临床收益的患者或病变类型,同时详细论述了PCI前如何使用IVUS或OCT优化支架尺寸(支架长度和直径)和手术策略的选择。此外,专家推荐对支架失败(支架内再狭窄或支架内血栓形成)的患者应常规进行冠状动脉内影像学检查,并首选OCT。最后,重点论述了IVUS和OCT在指导PCI和评估支架失败两个方面的优势和局限性,并对未来需要深入研究的领域进行了展望。 | Lorenz Raber Gary S Mintz Konstantinos C Koskinas Thomas W Johnson Niels R Holm Yoshinubo Onuma Maria D Radu Michael Joner Bo Yu Haibo Jia Nicolas Meneveau Jose M.de la Torre Hemandez Javier Escaned Jonathan Hill Francesco Prati Antonio Colombo Carlo di Mario Evelyn Regar Davide Capodanno William Wijns Robert A Byme Giulio Guagliumi | 2019 | 中华心血管病杂志2019，47，1： | 17 |
| 2 | Off-pump coronary artery bypass grafting versus optimal medical therapy alone:effectiveness of incomplete revascularization in high risk patients显示文摘有 multivessel 的 BackgroundGeriatric 病人冠的动脉疾病(CAD ) 是一个挑战性的组对待;这些盒子关于在这些病人上并且经常承担主要外科的实际利益在心队以内得到讨论导致放纵外科的选择。经皮的过程代表一种重要选择,但是冠的解剖可能是相反的。离开泵冠的动脉绕过(OPCAB ) 提供好质量没有暴露病人到的左前面的下降上的接枝(男孩) 心肺绕过,并且可能是在有多重 comorbidities 的病人的理想的选择,不是对合格经皮或在泵上过程。这研究的目的是没有经皮的选择在高风险的病人在中间的后续期间比较幸存,也与 OPCAB 对待或在回顾地从 2008 年 6 月评估到 2013 年 6 月的医药 therapy.MethodsWe 排出,有 multivessel CAD 的 83 个高风险的病人被包括:42 在男孩上用左内部乳房的动脉(LIMA ) 与不完全的离开泵 revascularization 被对待;41 在最佳的医药治疗(OMT ) 被解除,拒绝了外科。后续在 2015 年 3 月结束了,与一电话的会见。主要端点是从所有原因死亡的幸存;第二等的端点从非致命的主要不利心脏的事件(权标) 是从心脏相关的死亡和自由的幸存 .ResultsDuring 列在后面在上面,在 OPCAB 组的 11 死亡和在 OMT 组的 27 死亡发生了。死亡分别地由于在 6 和 15 个病人的心脏的因素。权标在 OMT 组在 OPCAB 组并且在 4 个病人在 6 个病人被观察。关于从所有原因死亡的幸存,经历了多于那些熬过的 OPCAB 的病人在 OMT 排出(木头等级 <0.001 ) ,并且 OMT 组带倾向 3.862 的调整分数的危险比率(P <0.001 ) 。关于从心脏相关的事件的幸存,经历了多于那些熬过的 OPCAB 的病人在 OMT 排出(木头等级 = 0.002 ) ,并且 OMT 组带倾向 3.663 的调整分数的危险比率(P = 0.010 ) 。有关从权标的自由没有统计上重要的差别(木头等级 = 0.273 ).ConclusionsFor 有 multivessel CAD 的高风险的病人,不是对在泵上合格完全的 revascularization 外科或经皮的过程,有 OPCAB LIMA-on-LAD 提议的不完全的 revascularization 在幸存受益什么时候与 OMT 相比独自一个。 | Filippo Prestipino Cristiano Spadaccio Antonio Nenna Fraser WH Sutherland Gwyn W Beattie Mario Lusini Francesco Nappi Massimo Chello | 2016 | Journal of Geriatric Cardiology2016，13，1： | 4 |
| 3 | A high-density, multi-parental SNP genetic map on apple validates a new mapping approach for outcrossing species显示文摘Quantitative trait loci(QTL)mapping approaches rely on the correct ordering of molecular markers along the chromosomes,which can be obtained from genetic linkage maps or a reference genome sequence.For apple(Malus domestica Borkh),the genome sequence v1 and v2 could not meet this need;therefore,a novel approach was devised to develop a dense genetic linkage map,providing the most reliable marker-loci order for the highest possible number of markers.The approach was based on four strategies:(i)the use of multiple full-sib families,(ii)the reduction of missing information through the use of HaploBlocks and alternative calling procedures for single-nucleotide polymorphism(SNP)markers,(iii)the construction of a single backcross-type data set including all families,and(iv)a two-step map generation procedure based on the sequential inclusion of markers.The map comprises 15417 SNP markers,clustered in 3 K HaploBlock markers spanning 1267 cM,with an average distance between adjacent markers of 0.37 cM and a maximum distance of 3.29 cM.Moreover,chromosome 5 was oriented according to its homoeologous chromosome 10.This map was useful to improve the apple genome sequence,design the Axiom Apple 480 K SNP array and perform multifamily-based QTL studies.Its collinearity with the genome sequences v1 and v3 are reported.To our knowledge,this is the shortest published SNP map in apple,while including the largest number of markers,families and individuals.This result validates our methodology,proving its value for the construction of integrated linkage maps for any outbreeding species. | Erica A Di Pierro Luca Gianfranceschi Mario Di Guardo Herma JJ Koehorst-van Putten Johannes W Kruisselbrink Sara Longhi Michela Troggio Luca Bianco Hélène Muranty Giulia Pagliarani Stefano Tartarini Thomas Letschka Lidia Lozano Luis Larisa Garkava-Gustavsson Diego Micheletti Marco CAM Bink Roeland E Voorrips Ebrahimi Aziz Riccardo Velasco François Laurens W Eric van de Weg | 2016 | Horticulture Research2016，3，1： | 3 |
| 4 | 22-gauge core vs 22-gauge aspiration needle for endoscopic ultrasound-guided sampling of abdominal masses显示文摘AIM To compare the aspiration needle(AN) and core biopsy needle(PC) in endoscopic ultrasound-guided fine needle aspiration(EUS-FNA) of abdominal masses.METHODS Consecutive patients referred for EUS-FNA were included in this prospective single-center trial. Each patient underwent a puncture of the lesion with both standard 22-gauge(G) AN(Echo Tip Ultra; Cook Medical, Bloomington, Indiana, United States) and the novel 22 G PC(Echo Tip Pro Core; Cook Medical, Bloomington, Indiana, United States) in a randomized fashion; histology was attempted in the PC group only. The main study endpoint was the overall diagnostic accuracy, including the contribution of histology to the final diagnosis. Secondary outcome measures included material adequacy, number of needle passes, and complications.RESULTS Fifty six consecutive patients(29 men; mean age 68 years) with pancreatic lesions(n = 38), lymphadenopathy(n = 13), submucosal tumors(n = 4), or others lesions(n = 1) underwent EUS-FNA using both of the needles in a randomized order. AN and PC reached similar overall results for diagnostic accuracy(AN: 88.9 vs PC: 96.1, P = 0.25), specimen adequacy(AN: 96.4% vs PC: 91.1%, P = 0.38), mean number of passes(AN: 1.5 vs PC: 1.7, P = 0.14), mean cellularity score(AN: 1.7 vs PC: 1.1, P = 0.058), and complications(none). A diagnosis on the basis of histology was achieved in the PC group in 36(64.3%) patients, and in 2 of those as the sole modality. In patients with available histology the mean cellularity score was higher for AN(AN: 1.7 vs PC: 1.0, P = 0.034); no other differences were of statistical significance.CONCLUSION Both needles achieved high overall diagnostic yields and similar performance characteristics for cytological diagnosis; histological analysis was only possible in 2/3 of cases with the new needle. | William Sterlacci Athanasios D Sioulas Lothar Veits Pervin G?nüllü Guido Schachschal Stefan Groth Mario Anders Christos K Kontos Theodoros Topalidis Andrea Hinsch Michael Vieth Thomas R?sch Ulrike W Denzer | 2016 | World Journal of Gastroenterology2016，22，39： | 2 |
| 5 | A seismic landslide susceptibility rating of geologic units based on analysis of characteristics of landslides triggered by the 17 January, 1994 Northridge, California earthquake显示文摘 | Mario Parise Randall W Jibson | 2000 | Engineering Geology2000，58，： | 1 |
| 6 | Design and implemen- tation of a highly efficient three-level T-type converter for low-voltage applications显示文摘 | Schweizer Mario Kolar Johann W | 2013 | IEEE Trans on Power Electronics2013，28，2： | 1 |
| 7 | Paul alivisatos semiconductor nanocrystals as fluorescent biological labels显示文摘 | Marcel Bruchez Jr Mario M Peter G Shimon W | 1998 | Science1998，281，： | 1 |
| 8 | Copula convergence theorems for tail events显示文摘 | Alessandro Juri Mario V. Wüthrich | 2002 | Insurance Mathematics and Economics2002，，3： | 1 |
| 9 | Current evidence for transurethral laser therapy of non-muscle invasive bladder cancer 显示文摘 | Mario W K Thorsten B Mathias W | 2011 | World J Urol2011，29，4： | 1 |
| 10 | A seismic landslide susceplibility rating of geologic units based on analysis of characteristics of landslides triggered by the 17 January, 1994 Northridge, California, earthquake 显示文摘 | Mario Parise Randall W Jibson | 2000 | Engineering Geology2000，58，34： | 1 |
| 11 | Cytotoxic T cells specifically induce fas on target cells, thereby facilitating exocytosis-independent induction of apoptosis显示文摘 | Markus M S Paul W Mario L | 2000 | J Immunol2000，165，： | 1 |
| 12 | Guidelines on myocardial revascularization The Task Force on Myocardial Revascularization of the European Society of Cardiology(ESC)and the European Association for Cardio-Thoracic Surgery(EACTS)显示文摘 | WIJNS W KOLH P DI MARIO C | 2010 | Eur Heart J2010，31，： | 1 |
| 13 | Engineering N-linked protein glycosylation with diverse O antigen lipopolysaccharide structures in Escherichia coli显示文摘 | Mario FF Michael W Marcela H | 2005 | Proc Natl Acad Sci USA2005，102，8： | 1 |
| 14 | Optical prop- erties of the TeO2-PbO-Li20-Nd2O3 glass system显示文摘 | RAFFAELLA R KARL G MARIO W etal | 2001 | Spec- trochimica Acta Part A2001，，57： | 1 |
| 15 | Optically controlled Millimeter Wave antenna显示文摘 | George W Webb Wayne Vernon Mario S | 1999 | IEEE MWP''99 Digest1999，，： | 1 |
| 16 | Substrate specificity of bacterial oligosaccharyltransferase suggests a common transfer mechanism for the bacterial and eukaryotic systems显示文摘 | Michael W Mario FF Mario FF | 2006 | Proc Natl Acad Sci USA2006，103，18： | 1 |
| 17 | Gradient pro- jection for sparse reconstruction: Application to com- pressed sensing and other inverse problems显示文摘 | Mario A T F Robert D N Stephen J W | 2007 | IEEE Journal of Selected Topics in Signal Processing2007，1，4： | 1 |
| 18 | Food scares and trust:a european study显示文摘 | MARIO M ALEXANDRA L BRUCE T W | 2008 | Journal of Agricultural Eco-nomics2008，59，1： | 1 |
| 19 | System Risk,Reinsurance,and the Failure of Crop Insurance Markets显示文摘 | Mario J M Joseph W G | 1997 | American Journal of Agricultural Economics1997，，79： | 1 |
| 20 | Cytotoxic T cells specifically induce Fas on Target cells, thereby facilitating exocytosis-independent induction of apoptosis显示文摘 | Markus M S Paul W Mario L | 2000 | J Immunol2000，165，7： | 1 |
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