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| 1 | Nat Biotechnol:将人星形胶质细胞重编程为多巴胺能神经元,有助治疗帕金森病显示文摘帕金森病是一种主要影响运动系统的神经退行性疾病。它的特征在于大脑中的多巴胺能神经元(dopaminergic neuron)渐进性丧失。尽管当前的疗法旨在补充多巴胺水平,但是没有一种疗法能够恢复这些丢失的细胞。如今。在一项新的研究中,来自瑞典、奥地利、西班牙和美国的研究人员开发出一种方法:将神经胶质细胞(glialcell)转化为活性的多巴胺能神经元,并且所产生的多巴胺能神经元能够部分恢复帕金森病模式小鼠的运动功能。这项概念验证研究可能为开发出一种治疗这种疾病的新方法铺平道路。 | Pia Rivetti di Val Cervo, Elisa Martín-Montañez, Enrique M Toledo, Gioele La Manno, Sara Padrell Sánchez, Sten Linnarsson Ernest Arenas Roman A Romanov, Christian Pifl Tibor Harkany Roman A Romanov, Giada Spigolon, Débora Masini, Michael Feyder, Tibor Harkany Gilberto Fisone Elisa Martín-Montañez Yi-Han Ng Marius Wernig | 2017 | 现代生物医学进展2017，17，17： | 11 |
| 2 | Efficiency of HAART in the prevention of mother to children HIV-1 transmission at Saint Camille medical centre in Burkina Faso,West Africa显示文摘Objective:To evaluate efficiency of HAART in the prevention of mother to child HIV transmission.Methods:A longitudinal study was conducted on 1 300 women attending the antenatal service at Saint Camille Medical Centre from September 2010 to July 2011.The HIV status of mothers was determined by rapid tests and EUSA.Discordant results were confirmed by real-time PCR.PCR was used to determine HIV status of children born from HIV-positive mothers.Results:Among 1 300 pregnant women tested for HIV,378 were seropositive.Mothers were predominantly housewives(69.7%),and their mean age was(28.32±0.15) years.The overall prevalence of HIV transmission from mother to child was 4.8%(18/378).This prevalence differed significantly from 0.0%(0/114) to 6.8%(18/264) in children born from mothers under HAART and those with mothers under New Prophylactic Protocol(ACT + 3TC + NVP),respectively(P< 0.01).Children’s mortality rate during the medical follow up was 1.3%(5/378).Among 16 women with HIV dubious status by ELISA,the Real Time PCR confirmed 2/16(12.5%) as HIV positive. Conclusions:The protocol of prevention of mother to children HIV transmission(PMTCT) is effective.The rate of HIV vertical transmission is significantly reduced.Early diagnosis determined by PCR of children born from HIV- positive mother is necessary and recommended in the context of PMTCT in Burkina Faso.We also found that PCR is an effective tool to confirm HIV status in pregnant women. | Laure Stella Ghoma Linguissi Cyrille Bisseye Tani Sagna Bolni Marius Nagalo Djeneba Ouermi Florencia W Djigma Salvatore Pignatelli Joseph D Sia Virginio Pietra Remy Moret Jean Baptiste Nikiema Jacques Simpore | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，12： | 4 |
| 3 | 基于纸张各向异性光散射性能测量建立光学网点增大数学模型显示文摘0引言
印刷品反射光谱是多种因素综合作用的结果,包括油墨与纸张的光谱反射特性、纸张内部的光散射情况,以及印刷流程和加网方法等。印刷系统特性如印刷色域或光学网点增大(Optical Dot Gain,ODG)受上述因素的直接影响。为了精确控制印刷流程, | Kathrin Happel Marius Walter Philipp Urban Edgar Drsam 李人劼(编译) | 2012 | 中国印刷与包装研究2012，4，1： | 2 |
| 4 | Two-state semiconductor laser selfmixing velocimetry exploiting coupled quantum-dot emission-states:Experiment,simulation and theory显示文摘 | Mari A G Marius D | 2014 | Optics Express2014，22，23： | 1 |
| 5 | Analytical and numerical stu dy on the maximum force developed by a V-beam thermal actuator显示文摘 | Radu S C Mircea C D Marius P | 2014 | Procedia Technology2014，12，： | 1 |
| 6 | Spatial Distribution of Ambrosia-Beetle Catches: A Possibly Useful Knowledge to Improve Mass-Trapping显示文摘 | Jean-Claude Grégoire Frédéric Piel Michel De Proft Marius Gilbert | 2001 | Integrated Pest Management Reviews2001，，： | 1 |
| 7 | The effectiveness of polyethylene versus titanium particles in inducing osteolysis in vivo显示文摘 | Marius von Knoch Donna E Jewison Jean D Sibonga Christoph Sprecher Bernard F Morrey Franz Loer Daniel J Berry Sean P Scully | 2003 | Journal of Orthopaedic Research2003，，2： | 1 |
| 8 | Single-phase fluid flow and mixing in microchinnels显示文摘 | VIMALK MARIUS P NIGAM K D P | 2011 | Chemical Engineering Science2011，66，： | 1 |
| 9 | Comparison of parameters calcu- lated from the BET and Freundlich isotherms obtained by nitrogen adsorption on activated carbons:A new method for calculating the specific surface area显示文摘 | Passe-Coutrin N Altenor S Cossement D Jean- Marius C Gaspard S | 2008 | Micro- porous and Mesoporous Materials2008，111，13： | 1 |
| 10 | C-Triazoly j3-D-furanosides as LpxC inhihitors: stereoselective synthesis and biological evalu- ation显示文摘 | Sunit K J Marius L Gonstantin G D | 2014 | Tetrahedron2014，70，： | 1 |
| 11 | Bioinformatic analysis of expressed sequence tags from grass shrimp palaemonetes pugio exposed to environmental stressors 显示文摘 | LI T D MARIUS B | 2009 | Comparative Biochemistry and Physiology D: Genomics and Proteomics2009，4，3： | 1 |
| 12 | Analysis of antibi- otics in urine and wipe samples from environmental and bi- ological monitoring-comparison of HPLC with UV-, single MS- and tandem MS-detection显示文摘 | Jochen T Marius R Dennis D | 2006 | Journal of Chromatog- raphy B2006，831，： | 1 |
| 13 | Identifying crosscutting concerns using fan-in analysis显示文摘 | Marius M Arie V D Leon M | 2007 | ACM Transactions on SoftwareEngineering and Methodology2007，17，1： | 1 |
| 14 | A Mathematical and Numer- ical Model for the Analysis of Hybrid Rocket Motors 显示文摘 | MARIUS S D FLORIN M | 2011 | Incas Bulletin2011，3，4： | 1 |
| 15 | A self-interest analysis of justice and tax compliance: How distributive jus- tice moderates the effect of outcome favorability 显示文摘 | PETER V MARIUS V D | 2007 | Journal of Economic Psychology2007，28，6： | 1 |
| 16 | Performance issues and error analysis in an open-domain question answering system 显示文摘 | D Moldovan Marius Pasea Sanda Harabagiu | 2003 | ACM Trans on Information Systems2003，21，2： | 1 |
| 17 | Identifying crosscutting concerns using fan-in analysis显示文摘 | Marius M Arie V D Leon M | 2007 | ACM Transactions on Software Engineering and Methodology2007，17，1： | 1 |
| 18 | Hydrophobicity and retention in reversed phase liquid chromatography 显示文摘 | Marius D' A Toshihiko H 1982 | 1982 | Journal of Liquid Chromatography and Related Technologies1982，5，2： | 1 |
| 19 | Positional sleep apnea in pa- tients with ischemic stroke 显示文摘 | Rainer D Benjamin H Marius H | 2008 | Neurolog Res2008，30，7： | 1 |
| 20 | Greater occipital nerve neuralgia caused by pathological arterial contact, treatment by surgical decompression 显示文摘 | Christiane Cornely M D Marius Fischer M D GiulioIngianni M D | 2011 | Headache the Journal of Head ~ Face Pain2011，51，4： | 1 |
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