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| 1 | 常规脂蛋白检测和载脂蛋白在心血管病预测中的比较显示文摘总胆固醇和高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)测量值对于心血管病风险评估至关重要,但对于其他脂质用于风险预测的效用一直存在争议。该研究纳入来自英国生物银行(Biobank)的无基线心血管病、未服用他汀类药物、有相关的脂质指标(n=346 686)的受试者。 | Welsh C Celis-Morales CA Brown R Mackay DF Lewsey J Mark PB Gray SR Ferguson LD Anderson JJ Lyall DM Cleland JG Jhund PS Gill J MR Pell JP Sattar N Welsh P 刘青(译) 叶鹏(摘、审校) | 2019 | 中华高血压杂志2019，27，7： | 10 |
| 2 | Testing for HCV Infection: An Update of Guidance for Clinicians and Laboratorians显示文摘 | Getchell Jane P Wroblewski Kelly E DeMaria Alfred Bean Christine L Parker Monica M Pandori Mark Dufour D Robert Busch Michael P Brecher Mark E Meyer William A Pesano Rick L Teo Chong-Gee Beckett Geoffrey A Araujo Aufra C Branson Bernard M D | 2013 | MMWR. Morbidity and Mortality Weekly Report2013，，18： | 3 |
| 3 | Percutaneous transluminal angioplasty balloons for endoscopic ultrasound-guided pancreatic duct interventions显示文摘BACKGROUND Endoscopic ultrasound(EUS)-guided main pancreatic duct(PD)access may be used when conventional endoscopic retrograde cholangiopancreatography(ERCP)techniques fail.The use of a percutaneous transluminal angioplasty balloon(PTAB),originally developed for vascular interventions,can be used to facilitate transmural(e.g.,transgastric)PD access and to dilate high-grade pancreatic strictures.AIM To describe the technique,efficacy,and safety of PTABs for EUS-guided PD interventions.METHODS Patients who underwent EUS with use of a PTAB from March 2011 to August 2021 were retrospectively identified from a tertiary care medical center supply database.PTABs included 3-4 French angioplasty catheters with 3-4 mm balloons designed to use over a 0.018-inch guidewire.The primary outcome was technical success.Secondary outcomes included incidence of adverse events(AEs)and need for early reintervention.RESULTS A total of 23 patients were identified(48%female,mean age 55.8 years).Chronic pancreatitis was the underlying etiology in 13(56.5%)patients,surgically altered anatomy(SAA)with stricture in 7(30.4%),and SAA with post-operative leak in 3(13.0%).Technical success was achieved in 20(87%)cases.Overall AE rate was 26%(n=6).All AEs were mild and included 1 pancreatic duct leak,2 cases of post-procedure pancreatitis,and 3 admissions for post-procedural pain.No patients required early re-intervention.CONCLUSION EUS-guided use of PTABs for PD access and/or stricture management is feasible with an acceptable safety profile and can be considered in patients when conventional ERCP cannulation fails. | Jad P AbiMansour Barham K Abu Dayyeh Michael J Levy Andrew C Storm John A Martin Bret T Petersen Ryan J Law Mark D Topazian Vinay Chandrasekhara | 2022 | World Journal of Gastrointestinal Endoscopy2022，14，8： | 2 |
| 4 | 无心血管病者尿钠排泄、血压与未来心血管病及死亡风险显示文摘高血压是心血管病的危险因素。代表膳食钠摄入的尿钠排泄增加与血压相关。但在一些观察性研究中,低钠摄入与死亡率增加相关。进一步研究应评估混杂相关性是否能解释钠摄入与预后的关系。研究者分析英国生物银行参加者(n=457484,平均年龄56.3岁,44.7%为男性)尿电解质与血压的数据。采用Kawasaki公式估算每日尿钠排泄量。研究者分析基线无心血管病、治疗的高血压或糖尿病者(n=322624)钠排泄与血压的关系,并评估钠排泄与致死性及非致死性心血管病、心力衰竭及死亡发生率的关系。 | Welsh CE Welsh P Jhund P Delles C Celis-Morales C Lewsey JD Gray S Lyall D Iliodromiti S Gill JMR Sattar N Mark PB 赵狄 练桂丽 | 2019 | 中华高血压杂志2019，27，6： | 2 |
| 5 | Exogenous cytokinin application to Actinidia chinensis var. deliciosa ‘Hayward’ fruit promotes fruit expansion through water uptake显示文摘Exogenous application of a cytokinin-like compound forchlorfenuron(CPPU)can promote fruit growth,although often at the expense of dry matter(DM),an important indicator of fruit quality.Actinidia chinensis var.deliciosa‘Hayward’fruit are very responsive to CPPU treatments,but the mechanism underlying the significant fruit weight increase and associated decrease in DM is unclear.In this study,we hypothesised that CPPU-enhanced growth increases fruit carbohydrate demand,but limited carbohydrate supply resulted in decreased fruit DM.During fruit development,CPPU effects on physical parameters,metabolites,osmotic pressure and transcriptional changes were assessed under conditions of both standard and a high carbohydrate supply.We showed that CPPU increased fruit fresh weight but the dramatic DM decrease was not carbohydrate limited.Enhanced glucose and fructose concentrations contributed to an increase in soluble carbohydrate osmotic pressure,which was correlated with increased water accumulation in CPPU-treated fruit and up-regulation of water channel aquaporin gene PIP2.4 at 49 days after anthesis.Transcipt analysis suggested that the molecular mechanism contributing to increased glucose and fructose concentrations was altered by carbohydrate supply.At standard carbohydrate supply,the early glucose increase in CPPU fruit was associated with reduced starch synthesis and increased starch degradation.When carbohydrate supply was high,the early glucose increase in CPPU fruit was associated with a general decrease in starch synthesis but up-regulation of vacuolar invertase and fructokinase genes.We conclude that CPPU affected fruit expansion by increasing the osmotically-driven water uptake and its effect was not carbohydrate supply-limited. | Simona Nardozza Helen L Boldingh Mark W Wohlers Andrew P Gleave Zhiwei Luo Guglielmo Costa Elspeth A MacRae Michael J Clearwater Annette C Richardson | 2017 | Horticulture Research2017，4，1： | 2 |
| 6 | On the 'downward control'of extratropical diabatic circulations by eddy-induced mean zonal forces显示文摘 | Haynes P H C J Marks M E McIntyre | 1991 | J Atmoa Sci1991，48，： | 1 |
| 7 | Efficient bump mapping hardware 显示文摘 | Mark P John A Brian C | 1997 | Computer Graphics Proceedings Annual Conference Series ACM S IGGRA PH Los Angeles California1997，1997，： | 1 |
| 8 | Design of stable steam injectors for continuous heating显示文摘 | Raj P Julie V Mark C | 1996 | Journal of Chemistry Technology and Biotecnology1996，66，： | 1 |
| 9 | “Vertically trans-ferred' overpressures in Brunei:Evidence for a new mecha-nism for the formation of high-magnitude overpressure显示文摘 | Mark R P Richard R H Richard E S C al | 2007 | Geology2007，35，11： | 1 |
| 10 | Altitudinal variation in stomatal condnncance,nitrogen content and leaf anatomy in different plant life forms in New Zealand显示文摘 | Ksrner C Bannister P Mark AF | 1986 | Oecologia1986，69，： | 1 |
| 11 | Histone deacetylase inhibitors:overview and perspectives显示文摘 | Dokmanovic M Clarke C Marks P A | 2007 | Mol Cancer Res2007，5，10： | 1 |
| 12 | Angioplasty for Symptomatic Intracranial Stenosis : Clinical Outcome 显示文摘 | Marks M P Wojak J C Al-Ali F | 2006 | Stroke2006，37，： | 1 |
| 13 | German-Austrian- Swiss Consensus Conference on clinical practice in chronic graft-versus-host disease(GVHD): guidance for supportive therapy of chronic cutaneous and musculoskeletal GVHD显示文摘 | Marks C Stadler M Hausetmann P | 2011 | Br J Derma- tol2011，165，1： | 1 |
| 14 | DNA sequence variation in the ribosomal internal transcribed spacer region of freshwater Cladophora species (Chlorophyta) 显示文摘 | Marks J C Cummings M P | 1996 | Journal of Phycology1996，32，： | 1 |
| 15 | The effects of land-uso history on soil properties and nutrient dynamics in northern hardwood forests of the ad- irondack mountains 显示文摘 | Larry E F Canham C D Marks P L | 2004 | Ecosystems2004，7，2： | 1 |
| 16 | Sensory descriptive texture analyses of cooked rice and its correlation to instrumental parameters using an extrusion cell显示文摘 | Meullenet J F C Gross J Marks B P | 1998 | Cereal Chemistry1998，75，5： | 1 |
| 17 | Threedimensional High-resolution Second-harmonic Generation Imaging of Endogenous Structural Proteins in Biological Tissues 显示文摘 | CAMPAGNOLA P J ANDREW C M MARK T | 2002 | Biophys J2002，81，1： | 1 |
| 18 | Estimation canopy chlorophyll concentration from field and airborne spectra 显示文摘 | Jago R A Mark E J C Curran P J | 1999 | Remote Sens Environ1999，68，： | 1 |
| 19 | Structure-property relationship of all-cellulose composites 显示文摘 | BENO J C ROGER H N MARK P S | 2009 | Comp Sci Tech2009，69，： | 1 |
| 20 | Growth factors protect neurons against ex- citotoxic/ischemic damages by stabilizing calcium homeostasis 显示文摘 | Mark P Mttson P BIN C | 1993 | Storke1993，12，： | 1 |
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