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| 1 | Significant association between ABO blood group and pancreatic cancer显示文摘AIM:To evaluate whether the ABO blood group is related to pancreatic cancer risk in the general population of the United States.METHODS:Using the University of Pittsburgh's clinicalpancreatic cancer registry,the blood donor database from our local blood bank (Central Blood Bank),and the blood product recipient database from the regional transfusion service (Centralized Transfusion Service) in Pittsburgh,Pennsylvania,we identified 274 pancreatic cancer patients with previously determined serological ABO blood group information.The ABO blood group frequency was compared between these patients and 708842 individual,community-based blood donors who had made donations to Pittsburgh's Central Blood Bank between 1979 and 2009.RESULTS:The frequency of blood group A was statistically significantly higher amongst pancreatic cancer patients compared to its frequency amongst the regional blood donors [47.63% vs 39.10%,odds ratio (OR)=1.43,P=0.004].Conversely,the frequency of blood group O was significantly lower amongst pancreatic cancer patients relative to the community blood donors (32.12% vs 43.99%,OR=0.60,P=0.00007).There were limited blood group B (n=38) and AB (n=17) pancreatic cancer patients;the overall P trend value comparing patient to donor blood groups was 0.001.CONCLUSION:The ABO blood group is associated with pancreatic cancer risk.Future studies should examine the mechanism linking pancreatic cancer risk to ABO blood group. | Julia B Greer Mark H Yazer Jay S Raval M Michael Barmada Randall E Brand David C Whitcomb | 2010 | World Journal of Gastroenterology2010，16，44： | 10 |
| 2 | Miniature gastrointestinal endoscopy: Now and the future显示文摘Since its original application,gastrointestinal(GI)endoscopy has undergone many innovative transformations aimed at expanding the scope,safety,accuracy,acceptability and cost-effectiveness of this area of clinical practice.One method of achieving this has been to reduce the caliber of endoscopic devices.We propose the collective term“Miniature GI Endoscopy”.In this Opinion Review,the innovations in this field are explored and discussed.The progress and clinical use of the three main areas of miniature GI endoscopy(ultrathin endoscopy,wireless endoscopy and scanning fiber endoscopy)are described.The opportunities presented by these technologies are set out in a clinical context,as are their current limitations.Many of the positive aspects of miniature endoscopy are clear,in that smaller devices provide access to potentially all of the alimentary canal,while conferring high patient acceptability.This must be balanced with the costs of new technologies and recognition of device specific challenges.Perspectives on future application are also considered and the efforts being made to bring new innovations to a clinical platform are outlined.Current devices demonstrate that miniature GI endoscopy has a valuable place in investigation of symptoms,therapeutic intervention and screening.Newer technologies give promise that the potential for enhancing the investigation and management of GI complaints is significant. | John J McGoran Mark E McAlindon Prasad G Iyer Eric J Seibel Rehan Haidry Laurence B Lovat Sarmed S Sami | 2019 | World Journal of Gastroenterology2019，25，30： | 4 |
| 3 | An analysis of multiple staging management strategies for carcinoma of the esophagus: computed tomography, endoscopic ultrasound, positron emission tomography, and thoracoscopy/laparoscopy显示文摘 | Michael B Wallace Paul J Nietert Craig Earle Mark J Krasna Robert H Hawes Brenda J Hoffman Carolyn E Reed | 2002 | The Annals of Thoracic Surgery2002，，4： | 2 |
| 4 | The role of ischemic preconditioning in the recruitment of rolling and adherent leukocytes in hepatic venules after ischemia/reperfusion显示文摘 | David E Sawaya J R Mark B | 1999 | J Surg Research1999，8，5： | 1 |
| 5 | A multibit E A modulator in floating-body SOS/SOI CMOS for extreme radiation environments显示文摘 | CHRISTOPHER F E WILLIAM R W MARK B | 1999 | IEEE J of Solid State Circuits1999，34，7： | 1 |
| 6 | Bacterial RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited condition 显示文摘 | Paolo C Dave W Robert J B Don C A Jay H Martin S Mark A Ganesh K Sara S Robert D Santiago N Stephanie B Mary F Jayaprakash T Santanu D Christopher B Michael H L Jacqueline E H | 2008 | Plant Physiology2008，147，2： | 1 |
| 7 | Science andtechnology for water purification in the coming decades显示文摘 | Mark A S Paul W B Menachem E | 2008 | Nature2008，452，： | 1 |
| 8 | Kok effect and the quantum yield of photosynthesis显示文摘 | Robert E S Mark A John S B | 1984 | Plant Physiology1984，75，： | 1 |
| 9 | Dual G1 and G2 phase inhibition by a novel selective CDC25 inhibitor 7-Chloro-6-(2-morpholin-4-ylethylamino) -quinoline-5,8-dione显示文摘 | LIXIA P ANDREW A A MARK E B | 2002 | J Biol Chem2002，277，46： | 1 |
| 10 | Chronic obstructive pulmonary disease: assessing and treating psychological issues in patients with COPD 显示文摘 | Angela B Mark E Melinda A | 2005 | Geriatrics2005，12，60： | 1 |
| 11 | Application of the analytical hierarchy process to establish health care waste management systems that minimise infection risks in developing countries 显示文摘 | Alan C Brent David E C Rogers Tsaletseng S M Ramabitsa-Siimane Mark B Rohwer | 2007 | European Journal of Operational Research 1812007，，： | 1 |
| 12 | Effcient Synthesis of Purine Analogues : an FeC13-SiO2-Promoted Cyclization Reaction of 4, 5-Diaminopyrimidines with Aldehydes Leading to 6,8,9-tri-Substituted Purines 显示文摘 | Qun D Brian S B Mark D E | 2000 | Tetrahedron Lett2000，41，： | 1 |
| 13 | Internal derangement of the wrist:indirect MR arthrography versus unenhanced MR imaging 显示文摘 | Andrew H Mark E William B | 2003 | Radiology2003，227，3： | 1 |
| 14 | Evaluation and analysis of soil washing for seven lead-contaminated soils显示文摘 | Mark R M William H Y | 1997 | Journal of Environmental Engineering1997，3，： | 1 |
| 15 | Seawater intrusion processes,investigation and management:Recent advances and future challenges显示文摘 | Adrian D W Mark B Vincent E A P | 2013 | Advances in Water Resources2013，51，3： | 1 |
| 16 | Limitations of MR imaging in the diagnosis of peripheral tears of the triangular fibrocartilage of the wrist显示文摘 | Andrew H Mark E William B | 2002 | AJR2002，178，2： | 1 |
| 17 | Spectral elec- tromyography assessment of back muscles in patients with low back pain undergoing rehabilitation 显示文摘 | Serge H R Carlo J D Mark E B S | 1995 | Spine1995，20，1： | 1 |
| 18 | Does algal morphology affect amphipod susceptibility to fish predation 显示文摘 | Maria B H Charles H P Mark E H | 1990 | Journal of Experimental Marine Biology and Ecology1990，139，： | 1 |
| 19 | Long-term safety and once-daily niacin/lovastatin formulation for patients with dyslipidemia 显示文摘 | Moti L K Mark E M Kathleen B | 2002 | Am J Cardiol2002，89，6： | 1 |
| 20 | Thermal stability of in situ filled siloxane elastomers 显示文摘 | Sohoni G B Mark J E | 1992 | Journal of Applied Polymer Science1992，45，10： | 1 |
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