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| 1 | Macrophage migration inhibitory factor gene polymorphisms in inflammatory bowel disease: An association study in New Zealand Caucasians and meta-analysis显示文摘AIM:To investigate the association of macrophage migration inhibitory factor(MIF)promoter polymorphisms with inflammatory bowel disease(IBD)risk.METHODS:One thousand and six New Zealand Caucasian cases and 540 Caucasian controls were genotyped for the MIF SNP-173G>C(rs755622)and the repeat polymorphism CATT5-8(rs5844572)using a predesigned TaqMan SNP assay and capillary electrophoresis,respectively.Data were analysed for single site and haplotype association with IBD risk and phenotype.Meta-analysis was employed,to assess cumulative evidence of association of MIF-173G>C with IBD.All published genotype data for MIF-173G>C in IBD were identified using PubMed and subsequently searching the references of all PubMed-identified studies.Imputed genotypes for MIF-173G>C were generated from the Wellcome Trust Case Control Consortium(and National Institute of Diabetes and Digestive and Kidney Diseases).Separate meta-analyses were performed on Caucasian Crohn’s disease(CD)(3863 patients,6031controls),Caucasian ulcerative colitis(UC)(1260 patients,1987 controls),and East Asian UC(416 patients and 789 controls)datasets using the Mantel-Haenszel method.The New Zealand dataset had 93%power,and the meta-analyses had 100%power to detect an effect size of OR=1.40 atα=0.05,respectively.RESULTS:In our New Zealand dataset,single-site analysis found no evidence of association of MIF polymorphisms with overall risk of CD,UC,and IBD or disease phenotype(all P values>0.05).Haplotype analysis found the CATT5/-173C haplotype occurred at a higher frequency in New Zealand controls compared to IBD patients(0.6 vs 0.01;P=0.03,OR=0.22;95%CI:0.05-0.99),but this association did not survive bonferroni correction.Meta-analysis of our New Zealand MIF-173G>C data with data from seven additional Caucasian datasets using a random effects model found no association of MIF polymorphisms with CD,UC,or overall IBD.Similarly,meta-analysis of all published MIF-173G>C data from East Asian datasets(416UC patients,789 controls)found no association of this promoter polymorphism with UC. | James D Falvey Robert W Bentley Tony R Merriman Mark B Hampton Murray L Barclay Richard B Gearry Rebecca L Roberts | 2013 | World Journal of Gastroenterology2013，19，39： | 9 |
| 2 | Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal carcinoma: an updated meta-analysis显示文摘 | Katrin M Sjoquist Bryan H Burmeister B Mark Smithers John R Zalcberg R John Simes Andrew Barbour Val Gebski | 2011 | Lancet Oncology2011，，7： | 4 |
| 3 | Tolllike receptor2 m ediates lipopolysaccharides induced cellular signaling显示文摘 | Yan R B Mark M R Gray A | 1998 | Nature1998，395，： | 2 |
| 4 | Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury显示文摘 | Caudrillier Axelle Kessenbrock Kai Gilliss Brian M Nguyen John X Marques Marisa B Monestier Marc Toy Pearl Werb Zena Looney Mark R | 2012 | EN2012，，7： | 2 |
| 5 | The role of ischemic preconditioning in the recruitment of rolling and adherent leukocytes in hepatic venules after ischemia/reperfusion显示文摘 | David E Sawaya J R Mark B | 1999 | J Surg Research1999，8，5： | 1 |
| 6 | A multibit E A modulator in floating-body SOS/SOI CMOS for extreme radiation environments显示文摘 | CHRISTOPHER F E WILLIAM R W MARK B | 1999 | IEEE J of Solid State Circuits1999，34，7： | 1 |
| 7 | The first en- antiomerieally pure thiadiazol-3-one 1-oxide and thiat- fiaza-indene 3-oxide systems chiral at the sulfur atom 显示文摘 | Benjamin R B Stephen P N Mark R J | 2010 | Tetrahedron: Asymmetry2010，21，： | 1 |
| 8 | Humoral immuno- globulins of the white sturgeon (Acipenser transmon- tanus):partial characterization of and recognition with monoclonal antibodies显示文摘 | Mark A Bascureo B Hedrick R P | 1996 | Developmental & Compar- ative Immunology1996，20，4： | 1 |
| 9 | Toll-like receptor 2 mediates lipoplysaccharide-induced celluar signalling 显示文摘 | Yang R B Mark M R Gray A | 1998 | Nature1998，395，6699： | 1 |
| 10 | Determinants of left ventricular mass and hypertrophy in hemodialysis patients assessed by cardiac magnetic resonance imaging显示文摘 | Patel R K Oliver S Mark P B | 2009 | Clin J Am Soc Nephrol2009，4，9： | 1 |
| 11 | Good strategy instructors are Constructivists 显示文摘 | PRESSLEY M HARRIA K R MARKS M B | 1992 | Educational Psychology Review1992，4，1： | 1 |
| 12 | Accurate transmission line characterization显示文摘 | WILLIAMS D F MARKS R B | 1993 | IEEE Microwave and Guided Wave Letters1993，3，8： | 1 |
| 13 | Histone deacetylase inhibi- tors : molecular mechanisms of action 显示文摘 | Xu W S Parmigiani R B Marks P A | 2007 | Oncogene2007，26，37： | 1 |
| 14 | Hemostatic function and progressing ischemic stroke D-dimer predicts early clinical progression显示文摘 | Mark B Peter L Ann R | 2004 | Stroke2004，35，： | 1 |
| 15 | Hemostatic function and progressing ischemic stroke D-dimer predicts early clinical progressi on显示文摘 | MARK B PETER L ANN R | 2004 | Stroke2004，35，6： | 1 |
| 16 | Natural-language Spatial Relations between Linear and Area Objects:The Topology and Metric of English-language Terms显示文摘 | SHARIFF A R B M EGENHOFER M J MARK D M | 1998 | International Journal of Geographical Information Science1998，12，3： | 1 |
| 17 | Theory of mind-based action in children form the autism spectrum显示文摘 | Sander B Carolien R Mark MT et a1 | 2003 | J Autism Dev Disord2003，33，5： | 1 |
| 18 | Step returns in threshold public goods: A meta -analysis and experimental analysis显示文摘 | Croson R T A M B Marks | 2000 | Experi- mental Economics2000，2，： | 1 |
| 19 | Using a Carton Nanotube Additive to Make Electrically Conductive Commercial Polymer Composites 显示文摘 | MARNI R MARK B RAM R | 2005 | SAMPE J2005，，2： | 1 |
| 20 | Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signaling 显示文摘 | ang R B Mark M R Gray A | 1998 | Nature1998，395，6699： | 1 |
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