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1篇 您的检索式:作者名="Mark SSmeltzer"
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1Pyroptosis and pyroptosis-inducing cancer drugs显示文摘Pyroptosis,an inflammatory form of lytic cell death,is a type of cell death mediated by the gasdermin(GSDM)protein family.Upon recognizing exogenous or endogenous signals,cells undergo inflammasome assembly,GSDM cleavage,the release of proinflammatory cytokines and other cellular contents,eventually leading to inflammatory cell death.In this review,we discuss the roles of the GSDM family for anti-cancer functions and various antitumor drugs that could activate the pyroptosis pathways.Fan Yang Sahana N.Bettadapura Mark SSmeltzer Hua Zhu Shanzhi Wang 2022Acta Pharmacologica Sinica2022,43,10:4
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