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| 1 | 金龙鱼(Scleropages:Osteoglossomorpha)化石的首次发现(英文)显示文摘金龙鱼化石的鳞片和骨骼碎片在过去时有报道,但鉴定并非十分可靠,因为在骨舌鱼科鱼类中这些鳞片和骨骼十分相似。首次记述了保存完美的金龙鱼化石,标本产于湖南湘乡下湾铺组和湖北松滋洋溪组,确立为骨舌鱼科金龙鱼属一新种:中华金龙鱼Scleropages sinensis sp.nov.。新种与现生金龙鱼(Scleropages)在头部骨骼、尾骨骼、各鳍的形状和位置以及具有网状鳞片等方面极为相似,因而归入该属。然而,新种在以下特征上不同于金龙鱼的现生种:鼻骨无纹饰,鼻骨上的感觉管显露于沟内,感觉管联合不经过顶骨,翼耳骨侧向加厚,眶前骨上的感觉孔大,眼眶后的眶下骨不完全覆盖前鳃盖骨上支,其宽高比例为0.75而非现生种的1–1.2,前鳃盖骨后下角变尖,鳃盖骨后下缘凹形、下端变尖,匙骨背突长大,脊椎46–48,椎体横突短小,胸鳍十分长大,上下两端的尾鳍条和内部鳍条等长。亚洲的现生种发现于各种河流和小溪中,比较喜欢水草茂盛的静水环境,一般游弋于表层水中,以鱼虾、昆虫等为食,新种中华金龙鱼也应该有相似的生长环境和食性。新种似具有性二形性,雄鱼体形略纤细,头部略大,口裂更深。中华金龙鱼化石的发现,说明金龙鱼属(Scleropages)和骨舌鱼属(Osteoglossum)在早始新世以前就已经分化,这对解释骨舌鱼类的跨洋分布具有十分重要的意义。 | 张江永 Mark V H WILSON | 2017 | 古脊椎动物学报2017，55，1： | 3 |
| 2 | Tenecteplase Reperfusion therapy in Acute ischaemic Cerebrovascular Events-Ⅱ (TRACE Ⅱ): rationale and design显示文摘Background and purpose Tenecteplase(TNK)is a promising agent for treatment of acute ischaemic stroke(AIS).We hypothesised that recombinant human TNK tissue-type plasminogen activator(rhTNK-tPA)is non-inferior to rt-PA in achieving excellent functional outcome at 90 days,when administered within 4.5 hours of ischaemic stroke onset.Methods and design Tenecteplase Reperfusion therapy in Acute ischemic Cerebrovascular Events(TRACE)is a phase Ⅲ,multicentre,prospective,randomised,open-label,blinded-end point non-inferiority study.Patients eligible for intravenous thrombolysis therapy are randomised to rhTNK-tPA 0.25 mg/kg(single bolus)to a maximum of 25 mg or rt-PA 0.9 mg/kg(10%bolus+90%infusion/1 hour)to a maximum of 90 mg.Medications considered necessary for the patient’s health may be given at the discretion of the investigator during 90-day follow-up.Study outcomes The primary study outcome is excellent functional outcome defined as modified Rankin Scale(mRS)0–1 at 90 days.Secondary efficacy outcomes include favourable functional outcome defined as mRS≤2 at 90 days,ordinal distribution of mRS and major neurological improvement on the National Institutes of Health Stroke Scale.Safety outcomes are symptomatic intracranial haemorrhage within 36 hours and death from any cause.Discussion There is no completed registration study of TNK in AIS worldwide.TRACE Ⅱ strives to provide evidence for a new drug application for rhTNK-tPA in AIS within 4.5 hours through a well-designed and rigorously executed randomised trial in China. | Shuya Li Bruce C V Campbell Lee H Schwamm Marc Fisher Mark Parsons Hao Li Yuesong Pan Yongjun Wang | 2022 | Stroke & Vascular Neurology2022，7，1： | 2 |
| 3 | A convenient synthesis of 3-alkythiophenes显示文摘 | Pham C V Mark H B Zimmer H | 1986 | Synthetic Communication1986，16，6： | 1 |
| 4 | A convenient synthesis of 3-alkylthiophenes显示文摘 | Pham C V Mark H B Zimmer H | 1986 | Synthetic Communications1986，16，6： | 1 |
| 5 | Gene selection from microarray data for cancer classification-a machinelearning approaeh显示文摘 | YU WANG IGOR V T MARK A H | 2005 | Computational Biology and Chemistry2005，，： | 1 |
| 6 | Treatment of traumatic cervical arteriovenous fistulas with N-butyl-2- cyanoacrylate 显示文摘 | Jayaraman M V Do H M Marks M P | 2007 | Am J Neuroradiol2007，28，2： | 1 |
| 7 | Cross-layer performance study of cooperative diversity system with ARQ显示文摘 | Mahinthan V Rutagemwa H Mark JW | 2009 | IEEE Transactions on Vehicular Technology2009，58，2： | 1 |
| 8 | Environ Sci Technol 显示文摘 | Snoeyink V L Weber W J Mark H B | 1969 | 3(10): 9181969，3，10： | 1 |
| 9 | A convenient synthesis of 3-alkylthiophenes显示文摘 | Mark H B Zimmer H | 1986 | Synthetic Communications1986，16，6： | 1 |
| 10 | Fabrication of ZnO nanorods and nanotubes in aqueous solutions显示文摘 | Li Q Kumar V Li Y Zhang H Marks T J Chang P H R | 2005 | Chem Mater2005，17，5： | 1 |
| 11 | Evaluation and analysis of soil washing for seven lead-contaminated soils显示文摘 | Mark R M William H Y | 1997 | Journal of Environmental Engineering1997，3，： | 1 |
| 12 | Predictive model for growth of Clostridium perfringens during cooling of cooked uncured beef显示文摘 | JUNEJA V K MARKS H THIPPAREDDI H | 2008 | Food Microbiology2008，25，1： | 1 |
| 13 | A convenient synthesis of 3-alkylthiophenes 显示文摘 | Mark H B Zimmer H | 1986 | Synthetic Communications1986，16，6： | 1 |
| 14 | The use of feed forward neural networks for machine vision calibration显示文摘 | Mark B L Cihan H D Mahesh V | 1999 | Production Economics1999，，1： | 1 |
| 15 | Model-Based Evaluation of Denitrifying P Removal in a two-sludge system显示文摘 | XIAODI H MARK C M LOOSDRECHT V | 2001 | Env2001，，2： | 1 |
| 16 | Relationship between cell shape and type of collagen synthesized as chondrocytes lose their cartilage phenotype in culture显示文摘 | Von der Mark K Gauss V vonder Mark H | 1977 | Nature1977，267，： | 1 |
| 17 | The immune system and hypertension 显示文摘 | Madhu V S Mark W C Sailesh C H | 2014 | Immunologic Research2014，29，13： | 1 |
| 18 | Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture显示文摘 | von der Mark K Gauss V von der Mark H | 1977 | Nature1977，267，5611： | 1 |
| 19 | Syn- thesis of some fluorinated phenylmethylsiloxane polymers and characterization of their surface properties 显示文摘 | PATWARDHAN D V ZIMMER H MARK J E | 1997 | Inorg Organo Polym1997，7，2： | 1 |
| 20 | Application ofthe theories of reasoned action and planned behavior toexercise behavior:a meta-analysis显示文摘 | Hansenblas H Carron A V Mark D E | 1997 | Journal of Sportand Exercise Psychology1997，19，： | 1 |
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