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| 1 | Removing Volatile Contaminants from the Unsaturated Zone by Inducing Advective Air-Phase Transport显示文摘 | Baehr A L Hoag G E Marley M C | 1989 | Journal of Contaminant Hydrology1989，，4： | 1 |
| 2 | Targeting Rho and Rho-kinase inthe treatment of cardiovascular disease 显示文摘 | Budzyn K Marley P D Sobey C G | 2006 | Trends in pharmacologicalsciences2006，27，2： | 1 |
| 3 | Coli surface antigens I and 3 of colonization factor antigen II-positive enterotoxigenic Escherichia coli:morphology,purification,and immune responses in humans显示文摘 | Levine MM Ristaino P Marley G | 1984 | Infect Immun1984，44，： | 1 |
| 4 | A comparison of the management of potentially malignant oral mucosal lesions by oral medicine practitioners and oral & maxillofacial surgeons in the UK显示文摘 | Marley J J Linden G J Cowan C G | 1998 | J Oral Pathol Med1998，27，10： | 1 |
| 5 | Fatigue Reassessment Applications:State-of-the-Art Paper显示文摘 | WILLIAM G B MARLEY M J MOHAMMADI J JIELSEN R J SARKANI S | 1997 | Journal of Structural Engineering1997，123，3： | 1 |
| 6 | Characterization of vitamin B12 immunoaffinity columns and method development for determination of vitamin B12 in a range of foods, juices and pharma- ceutical products using immunoaffinity clean - up and high performance liquid chromatography with UV detection 显示文摘 | Marley E C MacKay E Young G | 2009 | Food Additives & Contaminants2009，26，3： | 1 |
| 7 | Fatigue rdiability reassessment procedures : State-of-the-art paper 显示文摘 | William G Byers Mark J Marley Jamshid Mohammadi Richard J Nielsen and Shahram Sarkarfi | 1997 | J Struct Engrg ASCE1997，123，3： | 1 |
| 8 | Fatigue rdiability reassessment applications : State-of-the-art paper 显示文摘 | William G Byers Mark J Marley Jamshid Mohammadi Richard J Nielsen and Shahram Sarkarfi | 1997 | J Struct Engrg ASCE1997，123，3： | 1 |
| 9 | Removing volatile contaminants from the unsaturated zone by inducing advective air-phase transport显示文摘 | Baehr A L Hoag G E Marley M C | 1989 | J Contam Hydrol1989，4，： | 1 |
| 10 | Influence of temperature on the kinetics of adsorption and desorption of clavulanic acid by ionic exchange显示文摘 | Marlei Barboza Renata M R G Almeida Carlos O Hokka | 2003 | Biochemical Engineering Journal2003，14，： | 1 |
| 11 | The Cloning Expression and Tissue Distribution of Human PP2Cβ 显示文摘 | Marley A E Kline A Crabtree G | 1998 | FEBS Lett1998，431，1： | 1 |
| 12 | The effect of chlorhexidine gluconate as an endodontic irrigant on the apicalseal: long-term results显示文摘 | Ferguson D B Marley J T Hartwell G R | 2003 | J Endod2003，29，2： | 1 |
| 13 | Gasoline residual saturation in unsaturated uniform aquifer materials显示文摘 | HOAG G E MARLEY M C | 1986 | J Environ Eng1986，112，3： | 1 |
| 14 | Infectious causes of embryonic and fetal mortality显示文摘 | Daniel G M Marley M S D | 2008 | Theriogenology2008，70，3： | 1 |
| 15 | Removing volatile contaminants from the unsaturated zone by inducing advective air-phase transport显示文摘 | Baehr A L Hoag G E Marley M C | 1989 | Journal of Contaminant Hydrology1989，，4： | 1 |
| 16 | Removing volatile contaminants from the unsaturated zone by inducing ad- jective air - phase transport显示文摘 | BAEHR A L HOAG G E MARLEY M C | 1989 | Journal of Contaminant Hydrolo- gy1989，4，： | 1 |
| 17 | Fatigue Reliability Reassessment Procedures:State-of-the-Art Paper显示文摘 | Byers W G Marley M J Mohammadi J | | 0，，03： | 1 |
| 18 | 显示文摘 | BUDZYN K MARLEY P D SOBEY C G | 2006 | Trends Pharmaeol Sci2006，27，2： | 1 |
| 19 | Real-world treatment patterns and disease control over one year in patients with inflammatory bowel disease in Brazil显示文摘BACKGROUND Crohn’s disease(CD)and ulcerative colitis(UC)are inflammatory bowel diseases(IBDs)with a remission-relapsing presentation and symptomatic exacerbations that have detrimental impacts on patient quality of life and are associated with a high cost burden,especially in patients with moderate-to-severe disease.The Real-world Data of Moderate-to-Severe Inflammatory Bowel Disease in Brazil(RISE BR)study was a noninterventional study designed to evaluate disease control,treatment patterns,disease burden and health-related quality of life in patients with moderate-to-severe active IBD.We report findings from the prospective follow-up phase of the RISE BR study in patients with active UC or CD.AIM To describe the 12-mo disease evolution and treatment patterns among patients with active moderate-to-severe IBD in Brazil.METHODS This was a prospective,noninterventional study of adult patients with active Crohn’s disease(CD:Harvey-Bradshaw Index≥8,CD Activity Index≥220),inadequate CD control(i.e.,calprotectin>200μg/g or colonoscopy previous results),or active ulcerative colitis(UC:Partial Mayo score≥5).Enrollment occurred in 14 centers from October 2016 to February 2017.The proportion of active IBD patients after 9-12 mo of follow-up,Kaplan-Meier estimates of the time to mild or no activity and a summary of treatment initiation,discontinuation and dose changes were examined.RESULTS The study included 118 CD and 36 UC patients,with mean±SD ages of 43.3±12.6 and 44.9±16.5 years,respectively.The most frequent drug classes at index were biologics for CD(62.7%)and 5-aminosalicylate derivates for UC patients(91.7%).During follow-up,65.3%of CD and 86.1%of UC patients initiated a new treatment at least once.Discontinuations/dose changes occurred in 68.1%of CD patients[median 2.0(IQR:2-5)]and 94.3%of UC patients[median 4.0(IQR:3-7)].On average,CD and UC patients had 4.4±2.6 and 5.0±3.3 outpatient visits,respectively.The median time to first mild or no activity was 319(IQR:239-358)d for CD and 320(IQR:288-358)d for UC patients.At 9-12 mo,22.0%of CD and 20.0%of UC patients had active disease.CONCLUSION Although a marked proportion of active IBD patients achieved disease control within one year,the considerable time to achieve this outcome represents an unmet medical need of the current standard of care in a Brazilian real-world setting. | Ligia Yukie Sassaki Sender J Miszputen Roberto Luiz Kaiser Junior Wilson R Catapani Mauro Bafutto António S Scotton Cyrla Zaltman Julio Pinheiro Baima Hagata S Ramos Mikaell Alexandre Gouvea Faria Carolina D Gonçalves Isabella Miranda Guimaraes Cristina Flores Heda M B S Amarante Rodrigo Bremer Nones JoséMiguel Luz Parente Murilo Moura Lima Júlio Maria Chebli Maria de Lourdes Abreu Ferrari Julia F Campos Maria G P Sanna Odery Ramos Rogério Serafim Parra Jose J R da Rocha Omar Feres Marley R Feitosa Rosana Fusaro Caratin Juliana Tosta Senra Genoile Oliveira Santana | 2021 | World Journal of Gastroenterology2021，27，23： | 0 |
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