|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 2 | Building Community Consensus for Scientific Metadata with YAMZ显示文摘This paper reports on a demonstration of YAMZ(Yet Another Metadata Zoo)as a mechanism for building community consensus around metadata terms.The demonstration is motivated by the complexity of the metadata standards environment and the need for more user-friendly approaches for researchers to achieve vocabulary consensus.The paper reviews a series of metadata standardization challenges,explores crowdsourcing factors that offer possible solutions,and introduces the YAMZ system.A YAMZ demonstration is presented with members of the Toberer materials science laboratory at the Colorado School of Mines,where there is a need to confirm and maintain a shared understanding for the vocabulary supporting research documentation,data management,and their larger metadata infrastructure.The demonstration involves three key steps:1)Sampling terms for the demonstration,2)Engaging graduate student researchers in the demonstration,and 3)Reflecting on the demonstration.The results of these steps,including examples of the dialog provenance among lab members and voting,show the ease with YAMZ can facilitate building metadata vocabulary consensus.The conclusion discusses implications and highlights next steps. | Jane Greenberg Scott McClellan Christopher Rauch Xintong Zhao Mat Kelly Yuan An John Kunze Rachel Orenstein Claire Porter Vanessa Meschke Eric Toberer | 2023 | Data Intelligence2023，5，1： | 0 |
| 3 | An Automatic Approach to Extending the Consumer Health Vocabulary显示文摘Purpose: Given the ubiquitous presence of the internet in our lives, many individuals turn to the web for medical information. A challenge here is that many laypersons(as 'consumers') do not use professional terms found in the medical nomenclature when describing their conditions and searching the internet. The Consumer Health Vocabulary(CHV) ontology, initially developed in 2007, aimed to bridge this gap, although updates have been limited over the last decade. The purpose of this research is to implement a means of automatically creating a hierarchical consumer health vocabulary. This overall purpose is improving consumers' ability to search for medical conditions and symptoms with an enhanced CHV and improving the search capabilities of our searching and indexing tool HIVE(Helping Interdisciplinary Vocabulary Engineering).Design/methodology/approach: The research design uses ontological fusion, an approach for automatically extracting and integrating the Medical Subject Headings(Me SH) ontology into CHV, and further convert CHV from a flat mapping to a hierarchical ontology. The additional relationships and parent terms from Me SH allow us to uncover relationships between existing terms in the CHV ontology as well. The research design also included improving the search capabilities of HIVE identifying alternate relationships and consolidating them to a single entry.Findings: The key findings are an improved CHV with a hierarchical structure that enables consumers to search through the ontology and uncover more relationships.Research limitations: There are some cases where the improved search results in HIVE return terms that are related but not completely synonymous. We present an example and discuss the implications of this result. Practical implications: This research makes available an updated and richer CHV ontology using the HIVE tool. Consumers may use this tool to search consumer terminology for medical conditions and symptoms. The HIVE tool will return results about the medical term linked with the consumer term as well as the hierarchy of other medical terms connected to the term.Originality/value: This is a first attempt in over a decade to improve and enhance the CHV ontology with current terminology and the first research effort to convert CHV's original flat ontology structure to a hierarchical structure. This research also enhances the HIVE infrastructure and provides consumers with a simple, efficient mechanism for searching the CHV ontology and providing meaningful data to consumers. | Michal Monselise Jane Greenberg Ou Stella Liang Sonia Pascua Heejun Kim Mat Kelly Joan PBoone Christopher C.Yang | 2021 | Journal of Data and Information Science2021，6，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员