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| 1 | Diversity and distribution patterns of non-volant smallmammals along different elevation gradients on Mt. Kenya,Kenya显示文摘The distribution of small mammals in mountainous environments across different elevations can provide important information on the effects of climate change on the dispersal of species. However, few studies conducted on Afromontane ecosystems have compared the altitudinal patterns of small mammal diversity. We investigated the species diversity and abundance of non-volant small mammals(hereafter ‘small mammals')on Mt. Kenya, the second tallest mountain in Africa,using a standard sampling scheme. Nine sampling transects were established at intervals of 200 m on the eastern(Chogoria) and western(Sirimon) slopes.A total of 1 905 individuals representing 25 species of small mammals were trapped after 12 240 trap-nights.Abundance was highest at mid-elevations on both slopes.However, species richness and their distribution patterns differed between the two slopes. More species were recorded on Chogoria(24) than on Sirimon(17). On Chogoria, species richness was higher at mid-high elevations, with a peak at mid-elevation(2 800 m a.s.l.),whereas species richness showed little variation on the Sirimon slope. These results indicate that patterns of species diversity can differ between slopes on the same mountain. In addition, we extensively reviewed literature on Mt. Kenya's mammals and compiled a comprehensive checklist of 76 mammalian species. However, additional research is required to improve our understanding of smal mammal diversity in mountain habitats in Africa. | Simon Musila Zhong-Zheng Chen Quan Li Richard Yego Bin Zhang Kenneth Onditi Immaculate Muthoni Shui-Wang He Samson Omondi James Mathenge Esther N.Kioko Xue-Long Jiang | 2019 | Zoological Research2019，40，1： | 4 |
| 2 | The alkaloids of two species of Afrogalega 显示文摘 | Susag L Mathenge S Benn M | 2003 | Biochem Syst Ecol2003，31，6： | 1 |
| 3 | Identification and characterization of RNA-dependent RNA polymerase activity in recombinant Japanese encephalitis virus NS5 protein显示文摘 | F. Yu F. Hasebe S. Inoue E. G. M. Mathenge K. Morita | 2007 | Archives of Virology2007，，10： | 1 |
| 4 | When Lithium Hurts: A Look at Ebstein Anomaly显示文摘 | Stephen Osiro Kevin J. Tiwari Njambi Mathenge Jonier R. Rodriguez R. Shane Tubbs Marios Loukas | 2013 | Cardiology in Review2013，，5： | 1 |
| 5 | Urbanization, ethnicity and cardiovascular risk in a population in transition in Nakuru, Kenya: a population based survey 显示文摘 | Mathenge W Foster A Kuper H | 2010 | BMC Public Health2010，10，： | 1 |
| 6 | Core needle biopsy of breast cancer tumors increases dis- rant metastases in a mouse model 显示文摘 | Mathenge E G Dean C A Clements D etal | 2014 | Neoplasia2014，16，11： | 1 |
| 7 | Rapid assessment of avoidable blindness in Nakuru District, Kenya 显示文摘 | Mathenge W Kupper H Limburgh H | 2007 | Ophthalmology2007，114，3： | 1 |
| 8 | Rapid assessment of avoidable blindness in Nakuru District, Kenya显示文摘 | Mathenge W Kuper H Limburg H Polack S Onyango O Nyaga G | 2007 | Ophthalmology2007，114，3： | 1 |
| 9 | Socioeconomic posi- tion and later life prevalence of hypertension, diabetes and visual im- pairment in Nakuru, Kenya显示文摘 | Ploubidis GB Mathenge W De Stavola B | 2013 | Int J Public Health2013，58，1： | 1 |
| 10 | Rapid assessment of avoidable blindness in Nakuru district Kenya显示文摘 | Mathenge W Kuper H Limburg H | | 0，，： | 1 |
| 11 | Socioeconomic position and later life prevalence of hypertension,diabetes and visual impairment in Nakuru,Kenya显示文摘 | Ploubidis GB Mathenge W De Stavola B | 2013 | Int J Public Health2013，58，1： | 1 |
| 12 | Structure of the 40S ribosomal subunit of Plasmodium falciparum by homology and de novo modeling显示文摘Generation of three dimensional structures of macromolecules using in silico structural modeling technologies such as homology and de novo modeling has improved dramatically and increased the speed by which tertiary structures of organisms can be generated. This is especially the case if a homologous crystal structure is already available. High-resolution structures can be rapidly created using only their sequence information as input, a process that has the potential to increase the speed of scientific discovery. In this study, homology modeling and structure prediction tools such as RNA123 and SWISS–MODEL were used to generate the 40 S ribosomal subunit from Plasmodium falciparum. This structure was modeled using the published crystal structure from Tetrahymena thermophila, a homologous eukaryote. In the absence of the Plasmodium falciparum 40 S ribosomal crystal structure, the model accurately depicts a global topology, secondary and tertiary connections, and gives an overall root mean square deviation(RMSD) value of 3.9 ? relative to the template's crystal structure. Deviations are somewhat larger in areas with no homology between the templates. These results demonstrate that this approach has the power to identify motifs of interest in RNA and identify potential drug targets for macromolecules whose crystal structures are unknown. The results also show the utility of RNA homology modeling software for structure determination and lay the groundwork for applying thisapproach to larger and more complex eukaryotic ribosomes and other RNA-protein complexes. Structures generated from this study can be used in in silico screening experiments and lead to the determination of structures for targets/hit complexes. | Harrison Ndung'u Mwangi Peter Wagacha Peterson Mathenge Fredrick Sijenyi Francis Mulaa | 2017 | Acta Pharmaceutica Sinica B2017，7，1： | 0 |
| 13 | Genetic variation amongst biotypes of Dactylopius tomentosus显示文摘tomentose 胭脂虫规模昆虫, Dactylopius tomentosus (拉马克)(半翅类: Dactylopiidae ),是对 Cylindropuntia 的侵略种类的一个重要生物控制代理人( Caryophyllales : Cactaceae ).最近的研究证明了这规模在我们调查了的特别主人种类上与微分主人特性和健康由加盟主人的遗传因子型组成在D. tomentosus 遗传因子型和起源到之中的基因变化和种系发生的关系检验可能性那基因差异可能与他们的主人使用模式有关,并且他们的种系发生的关系是否将给卓见进他们的主人植物核苷酸顺序比较的分类相关,用 mitochondrial 细胞色素 c oxidase 的序列被完成我( COI )从一样的个人的基因序列在一个区域以内招待植物由唯一的 haplotype 相同、描绘属于的个人一样的遗传因子型但是然而从不同区域有类似的 haplotypes , haplotypes 没在种系发生的分析组织了的不同遗传因子型之间被分享 monophyletic D. tomentosus 进遗传因子型的 3 解决得好的 clades 种系发生的关系并且遗传因子型聚类与他们的主人的已知的分类相关相应二遗传因子型, Fulgida 和 Mamillata ,测试为 Wolbachia ( α-Proteobacteria )积极, Wolbachia 定序的昆虫的普通 endosymbiont 被使用昆虫特定的 COI DNA barcoding 教材意外收获地检测并且很类似于这研究是的 Wolbachia 超群 F 紧张胭脂虫遗传因子型的第一分子的描述和 Wolbachia 序列,用规模的主人特定的遗传因子型贡献胭脂虫昆虫并且到仙人掌的生物控制的遗传因子型的更好的鉴定。 | Catherine W. Mathenge Markus Riegler G. Andrew C. Beattie Robert N. Spooner-Hart Paul Holford | 2015 | Insect Science2015，22，3： | 0 |
| 14 | Bioefcacy and durability of Olyset® Plus, a permethrin and piperonyl butoxide-treated insecticidal net in a 3-year long trial in Kenya显示文摘Background:Long-lasting insecticide nets(LLINs)are a core malaria intervention.LLINs should retain efficacy against mosquito vectors for a minimum of three years.Efficacy and durability of Olyset®Plus,a permethrin and piperonyl butoxide(PBO)treated LLIN,was evaluated versus permethrin treated Olyset®Net.In the absence of WHO guidelines of how to evaluate PBO nets,and considering the manufacturer’s product claim,Olyset®Plus was evaluated as a pyrethroid LLIN.Methods:This was a household randomized controlled trial in a malaria endemic rice cultivation zone of Kirinyaga County,Kenya between 2014 and 2017.Cone bioassays and tunnel tests were done against Anopheles gambiae Kisumu.The chemical content,fabric integrity and LLIN survivorship were monitored.Comparisons between nets were tested for signifcance using the Chi-square test.Exact binomial distribution with 95%confdence intervals(95%CI)was used for percentages.The WHO efcacy criteria used were≥95%knockdown and/or≥80%mortality rate in cone bioassays and≥80%mortality and/or≥90%blood-feeding inhibition in tunnel tests.Results:At 36 months,Olyset®Plus lost 52%permethrin and 87%PBO content;Olyset®Net lost 24%permethrin.Over 80%of Olyset®Plus and Olyset®Net passed the WHO efcacy criteria for LLINs up to 18 and 12 months,respec‑tively.At month 36,91.2%Olyset®Plus and 86.4%Olyset®Net survived,while 72%and 63%developed at least one hole.The proportionate Hole Index(pHI)values representing nets in good,serviceable and torn condition were 49.6%,27.1%and 23.2%,respectively for Olyset®Plus,and 44.9%,32.8%and 22.2%,respectively for Olyset®Net but were not signifcantly diferent.Conclusions:Olyset®Plus retained efcacy above or close to the WHO efcacy criteria for about 2 years than Olyset®Net(1–1.5 years).Both nets did not meet the 3-year WHO efcacy criteria,and showed little attrition,comparable physical durability and survivorship,with 50%of Olyset®Plus having good and serviceable condition after 3 years.Better community education on appropriate use and upkeep of LLINs is essential to ensure efectiveness of LLIN based malaria interventions. | Paul M.Gichuki Luna Kamau Kiambo Njagi Solomon Karoki Njoroge Muigai Damaris Matoke‑Muhia Nabie Bayoh Evan Mathenge Rajpal S.Yadav | 2021 | Infectious Diseases of Poverty2021，10，6： | 0 |
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