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| 1 | Efficacy and safety of endoscopic prophylactic treatment with undiluted cyanoacrylate for gastric varices显示文摘AIM:To evaluate the efficacy and safety of undiluted N-butyl-2 cyanoacrylate plus methacryloxysulfolane(NBCM)as a prophylactic treatment for gastric varices(GV)bleeding.METHODS:This prospective study was conducted at a single tertiary-care teaching hospital between October 2009 and March 2013.Patients with portal hypertension(PH)and GV,with no active gastrointestinal bleeding,were enrolled in primary prophylactic treatment with NBCM injection without lipiodol dilution.Initial diagnosis of GV was based on endoscopy and confirmed with endosonography(EUS); the same procedure was used after treatment to confirm eradication of GV.After puncturing the GV with a regular injection needle,1 mL of undiluted NBCM was injected intranasally into GV.The injection was repeated as necessary to achieve eradication or until a maximum total volume of 3 mL of NBCM had been injected.Patients were followed clinically and evaluated with endoscopy at 3,6 and 12 mo.Later follow-ups were performed yearly.The main outcome measures were efficacy(GV eradication),safety(adverse events related to cyanoacrylate injection),recurrence,bleeding from GV and mortality related to GV treatment.RESULTS:A total of 20 patients(15 male)with PH and GV were enrolled in the study and treated with undiluted NBCM injection.Only 2(10%)patients had no esophageal varices(EV); 18(90%)patients were treated with endoscopic band ligation to eradicate EV before inclusion in the study.The patients were followed clinically and endoscopically for a median of 31 mo(range:6-40 mo).Eradication of GV was observed in all patients(13 patients were treated with 1 session and 7 patients with 2 sessions),with a maximum injected volume of 2 mL NBCM.One patient had GV recurrence,confirmed by EUS,at 6-mo follow-up,and another had late recurrence with GV bleeding after 35 mo of follow-up; overall,GV recurrence was observed in 2 patients(10%),after 6 and 35 mo of follow-up,and GV bleeding rate was 5%(1 patient).Mild epigastric pain was reported by 3 patients(15%).No mortality or major complications,including embolism,or damage to equipment were observed.CONCLUSION:Endoscopic injection with NBCM,without lipiodol,may be a safe and effective treatment for primary prophylaxis of gastric variceal bleeding. | Matheus Cavalcante Franco Gustavo Flores Gomes Frank Shigeo Nakao Gustavo Andrade de Paulo Angelo Paulo Ferrari Jr Ermelindo Della Libera Jr | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，6： | 16 |
| 2 | Occlusion of the anterior cerebral artery after head trauma显示文摘Intracranial arterial occlusion is rarely encountered in association with head injury.Only six cases of traumatic occlusion of the anterior cerebral artery(ACA) have previously been reported.In this paper,the authors describe a case of a posttraumatic occlusion of ACA.A 35-year-old male presented to the emergency room with severe head injury.Computed tomography(CT) scan displayed diffuse brain swelling with multiple skull fractures.Follow up CT scan showed extensive cerebral infarction in the territory of ACA.The patient underwent CT angiography that demonstrated occlusion of the ACA by a fracture of the anterior fossa.He died after 3 d.ACA traumatic occlusion is a rare condition,with poor prognosis.In this case,fracture was responsible for dissection and direct obstruction of the artery. | Wellingson Silva Paiva Almir Ferreira de Andrade Matheus Schmidt Soares Robson Luis Amorim Eberval Gadelha Figueiredo Manoel Jacobsen Teixeira | 2013 | World Journal of Radiology2013，5，5： | 7 |
| 3 | Perception of the esthetic impact of gingival smile on laypersons, dental professionals, and dental students显示文摘 | Matheus Melo Pithon Adrielle Mangabeira Santos Ana Carolina Dias Viana de Andrade Eloá Mangabeira Santos Felipe Santos Couto Raildo da Silva Coqueiro | 2012 | Oral Surgery Oral Medicine Oral Pathology and Oral Radiology2012，，： | 1 |
| 4 | Adsorption and preconcentration of divalent metal ions in fossil fuels and biofuels: Gasoline, diesel, biodiesel, diesel-like and ethanol by using chitosan microspheres and thermodynamic approach显示文摘 | Alexandre G.S. Prado Igor C. Pescara Sheila M. Evangelista Matheus S. Holanda Romulo D. Andrade Paulo A.Z. Suarez Luiz F. Zara | 2011 | Talanta2011，，3： | 1 |
| 5 | Adsorption and preconcentration of divalent metal ions in fossil fuels and biofuels: Gasoline, diesel, biodiesel, diesel-like and ethanol by using chitosan microspheres and thermodynamic approach显示文摘 | Alexandre G.S. Prado Igor C. Pescara Sheila M. Evangelista Matheus S. Holanda Romulo D. Andrade Paulo A.Z. Suarez Luiz F. Zara | 2011 | Talanta2011，，3： | 1 |
| 6 | Bridging the mental health treatment gap:effects of a collaborative care intervention(matrix support)in the detection and treatment of mental disorders in a Brazilian city显示文摘Objective To analyse temporal trends in diagnosis and treatment of mental disorders in primary care following implementation of a collaborative care intervention(matrix support).Design Dynamic cohort design with retrospective time-series analysis.Structured secondary data on medical visits to general practitioners of all study clinics were extracted from the municipal electronic records database.Annual changes in the odds of mental disorders diagnoses and antidepressants prescriptions were estimated by multiple logistic regression at visit and patient-year levels with diagnoses or prescriptions as outcomes.Annual changes during two distinct stages of the intervention(stage 1 when it was restricted to mental health(2005-2009),and stage 2 when it was expanded to other areas(2010-2015))were compared by adding year-period interaction terms to each model.Setting 49 primary care clinics in the city of Florianópolis,Brazil.Participants All adults attending primary care clinics of the study setting between 2005 and 2015.Results 3131983 visits representing 322100 patients were analysed.At visit level,the odds of mental disorder diagnosis increased by 13%per year during stage 1(OR 1.13,95%CI 1.11 to 1.14,p<0.001)and decreased by 5%thereafter(OR 0.95,95%CI 0.94 to 0.95,p<0.001).The odds of incident mental disorder diagnoses decreased by 1%per year during stage 1(OR 0.99,95%CI 0.98 to 1.00,p=0.012)and decreased by 7%per year during stage 2(OR 0.93,95%CI 0.92 to 0.93,p<0.001).The odds of antidepressant prescriptions in patients with a mental disorder diagnosis increased by 7%per year during stage 1(OR 1.07,95%CI 1.05 to 1.20,p<0.001);this was driven by selective serotonin reuptake inhibitor prescriptions which increased 14%per year during stage 1(OR 1.14,95%CI 1.12 to 1.18,p<0.001)and 9%during stage 2(OR 1.09,95%CI 1.08 to 1.10,p<0.001).The odds of incident antidepressant prescriptions did not increase during stage 1(OR 1.00,95%CI 0.97 to 1.02,p=0.665)and increased by 3%during stage 2(OR 1.03,95%CI 1.00 to 1.04,p<0.001).Changes per year were all significantly greater during stage 1 than stage 2(p values for interaction terms<0.05),except for antidepressant prescriptions during visits(p=0.172). | Sonia Saraiva Max Bachmann Matheus Andrade Alberto Liria | 2020 | Family Medicine and Community Health2020，8，4： | 0 |
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