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| 1 | Efficacy and safety of liquid nitrogen cryotherapy for treatment of Barrett's esophagus显示文摘AIM To evaluate the efficacy and safety of liquid nitrogen cryotherapy as a primary or rescue treatment for BE,with and without dysplasia,or intramucosal adenocarcinoma (IMC).METHODS This was a retrospective,single-center study carried out in a tertiary care center including 45 patients with BE who was treatment-na?ve or who had persistent intestinal metaplasia(IM),dysplasia,or IMC despite prior therapy.Barrett's mucosa was resected via EMR when clinically appropriate,then patients underwent cryotherapy until eradication or until deemed to have failed treatment.Surveillance biopsies were taken at standard intervals.RESULTS From 2010 through 2014,33 patients were studied regarding the efficacy of cryotherapy.Overall,29 patients (88%) responded to cryotherapy,with 84% having complete regression of all dysplasia and cancer.Complete eradication of cancer and dysplasia was seen in 75% of subjects with IMC; the remaining two subjects did not respond to cryotherapy.Following cryotherapy,15 patients with high-grade dysplasia (HGD) had 30% complete regression,50% IM,and 7% low-grade dysplasia (LGD); one subject had persistent HGD.Complete eradication of dysplasia occurred in all 5 patients with LGD.In 5 patients with IM,complete regression occurred in 4,and IM persisted in one.In 136 cryotherapy sessions amongst 45 patients,adverse events included chest pain (1%),stricture (4%),and one gastrointestinal bleed in a patient on dual antiplatelet therapy who had previously undergone EMR.CONCLUSION Cryotherapy is an efficacious and safe treatment modality for Barrett's esophagus with and without dysplasia or intramucosal adenocarcinoma. | Kristen Suchniak-Mussari Charles E Dye Matthew T Moyer Abraham Mathew Thomas J McGarrity Eileen M Gagliardi Jennifer L Maranki John M Levenick | 2017 | World Journal of Gastrointestinal Endoscopy2017,9,9: | 4 |
| 2 | Observation of Bose - Einstein condensation in a dilute atomic vapor显示文摘 | ANDERSON M H ENSHER J R MATHEWS M R | 1995 | Science1995,269,5221: | 2 |
| 3 | Molecular targets in the treatment of anxiety显示文摘 | Kent J M Mathew S J Gorman J M | 2002 | Biol Psychiatry2002,52,10: | 2 |
| 4 | Effect of corn moisture on the properties of pet food extrudates 显示文摘 | Hoseney R C Faubion J M | 1999 | Cereal Chemistry1999,76,6: | 1 |
| 5 | Synthesis, phase transition and thermal expansion studies on M2 MgWO6 ( M -: Ba^2+ and Sr^2+ ) double perovskites显示文摘 | Patwe S J Achary S N Mathews M D | 2005 | Journal of Alloys and Compounds2005,390,12: | 1 |
| 6 | Uhrasound guided vacuumassisted excision in the diagnosis and treatment of clinically benign breast lesions显示文摘 | Mathew J Crawford D J Lwin M | 2007 | Ann R Coll Surg Engl2007,5,4: | 1 |
| 7 | Characterization of the interlaminar fracture toughness of a laminated carbon/epoxy composite显示文摘 | Mathews M J Swanson S R | 2007 | Compos Sci Technol2007,67,: | 1 |
| 8 | National innovative capacity in East Asia显示文摘 | HU M Mathews J A | 2005 | Research Policy2005,34,9: | 1 |
| 9 | The Emotional Stroop Task and Psychopathology显示文摘 | WILLIAMS J M MATHEWS A MACLEOD C | | 0,,01: | 1 |
| 10 | Control of hyperhydricity of mango somatic embryos显示文摘 | MONSALUD M J MATHEWS H LITZ R E | 1995 | Plant Cell Tissue and Organ Culture1995,42,2: | 1 |
| 11 | Ultrasound guided vacuum-assisted excision in the diagnosis and treatment of clinically benign breast lesions显示文摘 | Mathew J Crawford D J Lwin M | 2007 | AnnR Coil Surg Engl2007,89,5: | 1 |
| 12 | Ultrasound guided vacllum assisted excision in the diagnosis and treatment of clinically benign breast lesions显示文摘 | Mathew J Crawford D J Lwin M | 2007 | Am R coil Surg Engl2007,89,5: | 1 |
| 13 | Prevalence of Tourette syndrome and chronic tics in the populationbased Avon longitudinal study of parents and children cohort显示文摘 | Scharf J M Miller L L Mathews C A | | 0,,02: | 1 |
| 14 | Report of the substudy assessing the impact of neurocognitive function on quality of life 5 years after cardiac surgery显示文摘 | NEWMAN M F GROCOTT H P MATHEW J P | 2001 | Stroke2001,32,12: | 1 |
| 15 | National Innovative Capacity in East Asia显示文摘 | Hu M C Mathews J A | 2005 | Research Policy2005,34,9: | 1 |
| 16 | Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure显示文摘 | Mathews D H Sabina J Zuker M | 1999 | Journal of Molecular Biology1999,288,5: | 1 |
| 17 | Incorporating chemi- cal modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure 显示文摘 | Mathews D H Disney M D Childs J L | 2004 | Proceedings of the National Academy of Sciences of the United States of America2004,101,19: | 1 |
| 18 | Genetic diversity of rotavirus genome segment 6(encoding VP6)in Pretoria,South Africa显示文摘 | MARTIN M N MATHEW D E KHUZWAYO C J | 2014 | SpringerPlus2014,3,179: | 1 |
| 19 | Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure显示文摘 | MATHEWS D H SABINA J ZUKER M | 1999 | Journal of Molecular Biology1999,288,5: | 1 |
| 20 | Bearing Sig- nature Analysis as a Medium for Fault Detection: A Re- view 显示文摘 | Patil M S Mathew J Rajendrakumar P K | 2008 | Journal of Tribology2008,130,1: | 1 |