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2篇 您的检索式：作者名="Mathilde Wagner"

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		题名	作者	年代	出处	被引量
	1	Unusual Hepatic Lesion in a Patient With a Lung Tumor显示文摘	Ben Hassen Wajih Wagner Mathilde Lucidarme Olivier	2014	Gastroenterology2014，，：	1
	2	Detection of liver micrometastases from colorectal origin by perfusion CT in a rat model显示文摘BACKGROUND: Some patients with colorectal carcinoma have liver metastases(LMs) which cannot be detected by conventional imaging. This study aimed to assess whether hepatic perfusion changes induced by micrometastases can be detected by perfusion computed tomography(CT).METHODS: LMs were produced in rats by injecting carcinoma cells into the portal vein. Perfusion CT was performed at microscopic(day 10), interval(day 17), and macroscopic stage(day 34). Perfusion parameters were computed using a dualinput one-compartmental model.RESULTS: Micro and macro LMs presented a mean diameter of 0.5 and 2.6 mm, respectively. Compared to controls, LMs at interval(1.1 mm) and macroscopic stage induced significant perfusion changes: a decrease of 42%(P=0.004) and 41%(P=0.029) in hepatic transit time and an increase of 292%(P=0.073) and 240%(P=0.001) in portal delay, respectively.CONCLUSIONS: LMs with a mean diameter between 1.1 and2.6 mm induced significant hepatic perfusion changes, detected by CT. Such detection may help to select patients and propose chemotherapy at the time of primary tumor resection.	Caroline Hatwell Magaly Zappa Mathilde Wagner Nicolas Michoux Valérie Paradis Valérie Vilgrain Léon Maggiori Yves Panis	2014	Hepatobiliary & Pancreatic Diseases International2014，13，3：	0

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