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		题名	作者	年代	出处	被引量
	1	Screening of the whole human cytochrome P450 complement(CYPome)with enzyme bag cocktails显示文摘We have previously introduced the use of permeabilized fission yeast cells(enzyme bags)that recombinantly express full-length CYPs for drug metabolism studies.Such enzyme bags are cells with pores that function as enzymes in situ.They can easily be prepared without a need for ultracentrifugation and may be used in similar protocols as microsomes.In this study we report the preparation of enzyme bag cocktails that permit the testing of multiple CYPs in a single enzyme bag reaction.Moreover,we established a convenient testing scheme that permits a rapid screen of all human CYPs for activity towards any given candidate substrate.An important aspect of this approach is the reduction of individual CYP test assays.If a cocktail containing many CYPs tests negative,it follows that all CYPs included in that cocktail need not be tested individually,thus saving time and resources.The new protocol was validated using two probe substrates.	Sangeeta Shrestha Sharma Shishir Sharma Matthias Bureik	2020	Journal of Pharmaceutical Analysis2020，10，3：	1
	2	Anti-CYP4Z1 autoantibodies detected in breast cancer patients显示文摘	Venkatrao Nunna Nasir Jalal Matthias Bureik	2017	Cellular & Molecular Immunology2017，14，6：	0

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