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5篇 您的检索式:作者名="Max Gassmann"
    题名 作者 年代 出处 被引量
1Erythropoietin modulates the neural control of hypoxic ventilation显示文摘Max Gassmann Jorge Soliz 2009Cellular and Molecular Life Sciences2009,,22:1
2Hypoxia Is Present in Murine Atherosclerotic Plaques and Has Multiple Adverse Effects on Macrophage Lipid Metabolism显示文摘Sajesh Parathath Stephanie L. Mick Jonathan E. Feig Victor Joaquin Lisa Grauer David M. Habiel Max Gassmann Lawrence B. Gardner Edward A. Fisher 2011Circulation Research2011,,10:1
3Red Blood Cell Volume and the Capacity for Exercise at Moderate to High Altitude显示文摘Robert A. Jacobs Carsten Lundby Paul Robach Max Gassmann 2012Sports Medicine2012,,8:1
4Trends and Determinants of Managing Virtual R&D Teams 显示文摘Gassmann Ofiver Max Zedtwitz 2003R&D Management2003,,3:1
5Exploiting moderate hypoxia to benefit patients with brain disease: Molecular mechanisms and translational research in progress显示文摘Hypoxia is increasingly recognized as an important physiological driving force.A specific transcriptional program,induced by a decrease in oxygen(O2)availability,for example,inspiratory hypoxia at high altitude,allows cells to adapt to lower O2 and limited energy metabolism.This transcriptional program is partly controlled by and partly independent of hypoxia-inducible factors.Remarkably,this same transcriptional program is stimulated in the brain by extensive motor-cognitive exercise,leading to a relative decrease in O2 supply,compared to the acutely augmented O2 requirement.We have coined the term“functional hypoxia”for this important demand-responsive,relative reduction in O2 availability.Functional hypoxia seems to be critical for enduring adaptation to higher physiological challenge that includes substantial“brain hardware upgrade,”underlying advanced performance.Hypoxia-induced erythropoietin expression in the brain likely plays a decisive role in these processes,which can be imitated by recombinant human erythropoietin treatment.This article review presents hints of how inspiratory O2 manipulations can potentially contribute to enhanced brain function.It thereby provides the ground for exploiting moderate inspiratory plus functional hypoxia to treat individuals with brain disease.Finally,it sketches a planned multistep pilot study in healthy volunteers and first patients,about to start,aiming at improved performance upon motor-cognitive training under inspiratory hypoxia.Hannelore Ehrenreich Max Gassmann Luise Poustka Martin Burtscher Peter Hammermann PhD Anna-Leena Sirén Klaus-Armin Nave Kamilla Miskowiak 2023Neuroprotection2023,1,1:0
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