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| 1 | 在血压控制不良的高血压患者中使用数字化干预的家庭和在线血压管理:随机对照试验显示文摘HOME BP试验(The home and online management and evaluation of blood pressure)的目的是评估在初级预防中结合自我监测和自我管理的数字化干预在高血压管理中的作用。研究者纳入英国76个治疗中心经过治疗但血压控制不好(>140/90 mm Hg, 1 mm Hg=0.133 kPa)并能上网的患者622例,进行自动确定主要终点的公开随机对照试验。 | McMa-nus RJ Little P Stuart B Morton K Raftery J Kelly J Bradbury K Zhang J Zhu S Murray E May CR Mair FS Michie S Smith P Band R Ogburn E AllenJ Rice C Nut-tall J Williams B Yardley L 陈嘉睿(译) 叶鹏(审校) | 2021 | 中华高血压杂志2021，29，5： | 15 |
| 2 | Metabolic syndrome does not affect sustained virologic response of direct-acting antivirals while hepatitis C clearance improves hemoglobin A1c显示文摘AIM To determine whether successful treatment with direc-tacting antivirals(DAA) is associated with improvements in hemoglobin A1 c(HbA1 c) and if type 2 diabetes mellitus(T2 DM) or metabolic syndrome affects sustained virologic response(SVR).METHODS We performed a retrospective analysis of all hepatitis C virus(HCV) patients at the VA Greater Los Angeles Healthcare System treated with varying DAA therapy between 2014-2016. Separate multivariable logistic regression was performed to determine predictors of HbA1 c decrease ≥ 0.5 after DAA treatment and predictors of SVR 12-wk post treatment(SVR12).RESULTS A total of 1068 patients were treated with DAA therapy between 2014-2016. The presence of T2 DM or metabolic syndrome did not adversely affect SVR12. 106 patients had both HCV and T2 DM. Within that cohort,patients who achieved SVR12 had lower mean HbA1 c pre treatment(7.35 vs 8.60,P = 0.02),and lower mean HbA1 c post-treatment compared to non-responders(6.55 vs 8.61,P = 0.01). The mean reduction in HbA1 c after treatment was greater for those who achieved SVR12 than for non-responders(0.79 vs 0.01,P = 0.03). In adjusted models,patients that achieved SVR12 were more likely to have a HbA1 c decrease of ≥ 0.5 than those that did not achieve SVR12(adjusted OR = 7.24,95%CI: 1.22-42.94). CONCLUSION In HCV patients with T2 DM,successful treatment with DAA was associated with a significant reduction in HbA1 c suggesting that DAA may have a role in improving insulin sensitivity. Furthermore,the presence of T2 DM or metabolic syndrome does not adversely affect SVR12 rates in patients treated with DAA. | Tien S Dong Elizabeth S Aby Jihane N Benhammou Jenna Kawamoto Steven-Huy Han Folasade P May Joseph R Pisegna | 2018 | World Journal of Hepatology2018，10，9： | 4 |
| 3 | The invasion persistence, and spread of infectious diseases within animal and plant communites显示文摘 | Anderson R M May R M | 1986 | Phil Trans R Soc London1986，314，： | 2 |
| 4 | Simple mathematical models with very complicated dynamics显示文摘 | May R M | 1976 | Nature1976，261，： | 2 |
| 5 | Direct coronary vasodilator action of adrenomedullin is mediated by nitric oxide显示文摘 | De MATTEO R MAY C N | 2003 | Br J Pharmacol2003，140，8： | 2 |
| 6 | Imaging pancreatobiliary ductal system with optical coherence tomography: A review显示文摘An accurate, noninvasive and cost-effective method of in situ tissue evaluation during endoscopy would be highly advantageous for the detection of dysplasia or early cancer and for identifying different disease stages. Optical coherence tomography(OCT) is a noninvasive, high-resolution(1-10 μm) emerging optical imaging method with potential for identifying microscopic subsurface features in the pancreatic and biliary ductal system. Tissue microstructure of pancreaticobiliary ductal system has been successfully imaged by inserting an OCT probe through a standard endoscope operative channel. High-resolution OCT images and the technique's endoscopic compatibility have allowed for the microstructural diagnostic of thepancreatobiliary diseases. In this review, we discussed currently available pancreaticobiliary ductal imaging systems to assess the pancreatobiliary tissue microstructure and to evaluate varieties of pancreaticobiliary disorders and diseases. Results show that OCT can improve the quality of images of pancreatobiliary system during endoscopic retrograde cholangiopancheatography procedure, which may be important in distinguishing between the neoplastic and non-neoplastic lesions. | Mohammad S Mahmud Gray R May Mohammad M Kamal Ahmed S Khwaja Carry Sun Alex Vitkin Victor XD Yang | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，11： | 2 |
| 7 | Complications and monitoring of OKT3 therapy 显示文摘 | Thistlethwaite J R Stuart J K Mayes J T | 1998 | AM J Kidney Dis1998，11，2： | 2 |
| 8 | Differences in number and area of mesocarp cells between small and large-fruited peach cultivars显示文摘 | SCORZA R MAY L G PURNELL B UPCHURCH B | 1991 | J Amer Soc Hort Sci1991，116，： | 1 |
| 9 | Potentiation of platelet aggregation by heparin in human whole blood is attenuated by P2Y12 and P2Y1 antagonists but not aspirin显示文摘 | Storey R F May J A Heptinstall S | 2005 | Thromb Res2005，115，4： | 1 |
| 10 | Possible demographic consequences of HIV/AIDS显示文摘 | May R M Anderson R M McLean A R | 1988 | Math Biosci1988，90，： | 1 |
| 11 | Reducing the effect of ground clutter on wind profiler velocity measurements显示文摘 | May P T R G Strauch | 1998 | J Atmos Oceanic Tech1998，15，： | 1 |
| 12 | Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘 | Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J | 2004 | Proc Natl Acad Sci USA2004，101，26： | 1 |
| 13 | Flow-based multiadsorbate ellipsometric porosimetry for the characterization of mesoporous Pt- TiO2 and Au-TiO2 nanocomposites显示文摘 | May R A Patel M N Johnston K P | 2009 | Langmuir2009，25，8： | 1 |
| 14 | How many species are there on earth? 显示文摘 | May R M | 1989 | Science1989，241，： | 1 |
| 15 | Software unit test coverage and adequacy 显示文摘 | ZHUH HALL P A V MAY J H R | 1997 | ACM Computing Surveys1997，29，4： | 1 |
| 16 | Accumulation of mes-senger ribonucleic acid specific for extracellular protease in Bacillus subtilis 168显示文摘 | Semets E V Glenn A R May B K | | 0，，02： | 1 |
| 17 | Mortality of HIV-in- fected patients starting potent antiretroviral therapy:com- parison with the general population in nine industrialized countries显示文摘 | Zwahlen M Harris R May M | 2009 | Int J Epidemiol2009，38，6： | 1 |
| 18 | Measures Used in Assessing Outcomes of School-Wide Positive Behavior Support显示文摘 | Brandt R Chitiyo M May E | 2012 | Journal of Research in Special Educational Needs2012，，4： | 1 |
| 19 | Enhanced reduc-tivedechlorination of polychlorinated biphenyl impactedsediment by bioaugmentation with a dehalorespiring bac-terium 显示文摘 | Payne R B May H D Sowers K R | 2011 | Environmental science & technology2011，45，20： | 1 |
| 20 | Evolutionary games and spatial chaos显示文摘 | Nowak M A May R M | 1992 | Nature1992，359，6398： | 1 |
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